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Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998. Additionally we are shipping Osteoclast Stimulating Factor 1 Kits (32) and Osteoclast Stimulating Factor 1 Proteins (20) and many more products for this protein.
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Data show that SH3P2 was phosphorylated on Ser (show SIGLEC1 Antibodies)(202) by ribosomal S6 kinase (show RPS6KB1 Antibodies) (RSK (show RPS6KA1 Antibodies)) in an ERK (show EPHB2 Antibodies) pathway-dependent manner, and such phosphorylation inhibited the ability of SH3P2 to suppress cell motility.
SH3P2, a novel component of adhesion sites, is involved in Cbl (show CBL Antibodies) and Src (show SRC Antibodies)-mediated pathways
The SH3 domain (show ITSN1 Antibodies) structure of osteoclast stimulating factor at atomic resolution provides an accurate framework for structure-based design of its inhibitors.
The peptide-binding groove of OSTF-SH3 domain adopts a conformation different from other SH3 domains and probably needs a conformational switch for binding to its proline-rich ligand; this status is possibly regulated by the C-terminal ankyrin repeats.
findings link pleiotrophin abundance in gliomas with survival in humans and mice, and show that pleiotrophin promotes glioma progression through increased VEGF deposition and vascular abnormalization.
antagonizes Brd2 (show BRD2 Antibodies) promoting cell differentiation associated with the neural tube: spinal cord neurogenesis and neural crest migration
PTN-mediated hematopoietic regeneration occurs in a RAS-dependent manner.
the absence of PTN (show PTN Antibodies) in vivo is associated with disruption of specific cognitive and affective processes
The results of this study indicated that PTN (show PTN Antibodies) may be a novel genetic factor of importance in alcohol use disorders.
data suggest that the spinal antinociceptive effects caused by stimulation of alpha2-adrenoceptors are differentially regulated by endogenous expression of PTN (show PTN Antibodies)
PTN (show PTN Antibodies) overexpression exerts various effects on sarcolemma ion channel expression/function and resting cytosolic calcium concentrations in soleus and extensor digitorum longus muscles.
Vivarium-housed Wt controls had higher levels of active TGF-beta1 (show TGFB1 Antibodies) and IL-2 (show IL2 Antibodies) in inguinal lymph nodes relative to PTN (show PTN Antibodies)-Tg mice.
Pleiotrophin (show PTN Antibodies) exerts a neuroprotective role against amphetaine-induced neurotoxicity in striatum.
the data demonstrate that maintenance of amphetamine-induced conditioning effects depend on the endogenous expression of PTN (show PTN Antibodies).
Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998
osteoclast stimulating factor 1
, osteoclast-stimulating factor 1
, SH3 domain protein 3
, heparin affin regulatory peptide
, heparin-binding brain mitogen
, heparin-binding growth factor 8
, heparin-binding growth-associated molecule
, heparin-binding neurite promoting factor
, heparin-binding neurotorphic factor
, heparin-binding neutrophic factor
, osteoblast-specific factor 1
, osteoblastic cell factor