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involved in regulation of bone formation and mineralization. Additionally we are shipping Osteocrin Kits (26) and Osteocrin Proteins (8) and many more products for this protein.
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osteocrin represents a novel, unique vitamin D-regulated bone-specific protein that appears to act as a soluble osteoblast regulator
Foxo1 (show FOXO1 Antibodies) downregulates musclin mRNA expression both in vitro and in vivo, which should explain insulin (show INS Antibodies)-mediated upregulation of this gene in muscle cells.
Ostn is a naturally occurring ligand of the NPR-C (show NPR3 Antibodies) clearance receptor and may act to locally modulate the actions of the natriuretic system in bone by blocking the clearance action of NPR-C (show NPR3 Antibodies), thus locally elevating levels of C-type natriuretic peptide (show NPPC Antibodies).
Data show that musclin (Ostn) production is stimulated by Ca2 (show CA2 Antibodies)+-dependent proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-Akt (Akt (show AKT1 Antibodies)) phosphorylation.
findings suggest that palmitate increases musclin gene expression via the activation of the PERK signaling pathway in C2C12 myotubes
Musclin expression level is tightly regulated by nutritional changes and its physiological role could be linked to glucose metabolism
we detected 2 SNPs, A85C and T335C, that were located on the 3rd exon and the 3 untranslated regions of the bovine Osteocrin gene, respectively, using 413 Qinchuan cattle DNA samples.
involved in regulation of bone formation and mineralization