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involved in regulation of bone formation and mineralization [RGD, Feb 2006].. Additionally we are shipping Osteocrin Antibodies (81) and Osteocrin Kits (26) and many more products for this protein.
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Human OSTN Protein expressed in Escherichia coli (E. coli) - ABIN667413
Bord, Ireland, Moffatt, Thomas, Compston: Characterization of osteocrin expression in human bone. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005
Show all 2 references for ABIN667413
osteocrin represents a novel, unique vitamin D-regulated bone-specific protein that appears to act as a soluble osteoblast regulator
Foxo1 (show FOXO1 Proteins) downregulates musclin mRNA expression both in vitro and in vivo, which should explain insulin (show INS Proteins)-mediated upregulation of this gene in muscle cells.
Ostn is a naturally occurring ligand of the NPR-C (show NPR3 Proteins) clearance receptor and may act to locally modulate the actions of the natriuretic system in bone by blocking the clearance action of NPR-C (show NPR3 Proteins), thus locally elevating levels of C-type natriuretic peptide (show NPPC Proteins).
Data show that musclin (Ostn) production is stimulated by Ca2 (show CA2 Proteins)+-dependent proto-oncogene (show RAB1A Proteins) protein c (show PROC Proteins)-Akt (Akt (show AKT1 Proteins)) phosphorylation.
findings suggest that palmitate increases musclin gene expression via the activation of the PERK signaling pathway in C2C12 myotubes
Musclin expression level is tightly regulated by nutritional changes and its physiological role could be linked to glucose metabolism
we detected 2 SNPs, A85C and T335C, that were located on the 3rd exon and the 3 untranslated regions of the bovine Osteocrin gene, respectively, using 413 Qinchuan cattle DNA samples.
involved in regulation of bone formation and mineralization