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Otopetrin 1 Proteins (OTOP1)

Required for normal formation of otoconia in the inner ear. Additionally we are shipping Otopetrin 1 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OTOP1 133060 Q7RTM1
OTOP1 21906 Q80VM9
Rat OTOP1 OTOP1 305427 Q7M734
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Top Otopetrin 1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

OTOP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Otopetrin 1 (OTOP1) Interaction Partners

Mouse (Murine) Otopetrin 1 (OTOP1) interaction partners

  1. Otop1 defines a unique target of cytokine signaling that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity.

  2. Data show that tlt and mlh mutations uncouple Otopetrin 1 from inhibition of P2Y (show P2RY1 Proteins) receptor function.

  3. OTOP1 is expressed at the apex (show APEX1 Proteins) of supporting cells. It increases cytosolic Ca in response to purinergic agonists by blocking mobilization of Ca from intracellular stores in an extracellular Ca-dependent manner & by mediating extracellular Ca influx.

  4. Otopetrin 1 encodes a multi-transmembrane domain protein expressed in the developing otocyst. Mouse mutants tilted and mergulhador carry recessive mutations in Otop1 that result in otoconial agenesis without causing collateral deafness.

Otopetrin 1 (OTOP1) Protein Profile

Protein Summary

Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity).

Gene names and symbols associated with Otopetrin 1 Proteins (OTOP1)

  • otopetrin 1 (OTOP1)
  • otopetrin 1 (Otop1)
  • A530025J20Rik protein
  • Otp1 protein
  • tlt protein

Protein level used designations for Otopetrin 1 Proteins (OTOP1)

otopetrin 1 , otopetrin-1-like , otopetrin-1 , tilted

GENE ID SPECIES
422844 Gallus gallus
471127 Pan troglodytes
488825 Canis lupus familiaris
525643 Bos taurus
712780 Macaca mulatta
100229440 Taeniopygia guttata
100348548 Oryctolagus cuniculus
100443603 Pongo abelii
100478239 Ailuropoda melanoleuca
100524096 Sus scrofa
100544599 Meleagris gallopavo
100599424 Nomascus leucogenys
133060 Homo sapiens
21906 Mus musculus
305427 Rattus norvegicus
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