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Oxidative-Stress Responsive 1 (OXSR1) ELISA Kits

The product of OXSR1 belongs to the Ser/Thr protein kinase family of proteins. Additionally we are shipping Oxidative-Stress Responsive 1 Antibodies (106) and Oxidative-Stress Responsive 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
OXSR1 9943 O95747
Anti-Rat OXSR1 OXSR1 316064  
OXSR1 108737 Q6P9R2
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Top Oxidative-Stress Responsive 1 ELISA Kits at antibodies-online.com

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Human
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$380.00
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$450.00
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Human
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$875.60
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Mouse
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$875.60
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Pig
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$1,029.60
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More ELISA Kits for Oxidative-Stress Responsive 1 Interaction Partners

Human Oxidative-Stress Responsive 1 (OXSR1) interaction partners

  1. the WNK-regulated SPAK (show STK39 ELISA Kits)/OSR1 kinases directly phosphorylate the N[K]CCs (show CCS ELISA Kits) and KCCs, promoting their stimulation and inhibition respectively.

  2. SPAK (show STK39 ELISA Kits) and OSR1, which are often coexpressed in cells, can form functional heterodimers.

  3. Data show that intracellular association between WNK1 (show WNK1 ELISA Kits) and oxidative stress-responsive 1 (OSR1) is required for stimulation of OSR1 and Na(+), K(+), Cl(-)-Cotransporter NKCC1 (show SLC12A2 ELISA Kits) and NKCC2 (show SLC12A1 ELISA Kits) activities by osmotic stress.

  4. OXSR1 and WNK3 (show WNK3 ELISA Kits) transcripts were substantially overexpressed in subjects with schizophrenia relative to comparison subjects.

  5. isolation and characterization of OSR1 (oxidative stress-responsive 1), one of two human Fray homologs. OSR1 is a 58-kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines

  6. WNK1 (show WNK1 ELISA Kits) and SPAK (show STK39 ELISA Kits)/OSR1 mediate the hypotonic stress signaling pathway to cation-chloride-coupled cotransporters

  7. OXSR1 kinase is shown to interact with the three RELT (show RELT ELISA Kits) family members RELT (show RELT ELISA Kits), RELL1, and RELL2 by in vitro co-immunoprecipitation; additionally, OXSR1 phosphorylates RELT (show RELT ELISA Kits) family members in an in vitro kinase assay.

  8. data establish that the CCT (show FLVCR2 ELISA Kits) domain functions as a multipurpose docking site, enabling SPAK (show STK39 ELISA Kits)/OSR1 to interact with substrates (NKCC1 (show SLC12A2 ELISA Kits)) and activators (WNK1 (show WNK1 ELISA Kits)/WNK4 (show WNK4 ELISA Kits))

  9. OSR1 and sterile20-related, proline-, alanine-rich kinase are likely links between WNK lysine deficient protein kinase 1 and solute carrier family 12 in a pathway that contributes to volume regulation and blood pressure homeostasis in mammals

  10. These results provide the first molecular insight into the mechanism by which the SPAK (show STK39 ELISA Kits) and OSR1 kinases specifically recognize their upstream activators and downstream substrates.

Mouse (Murine) Oxidative-Stress Responsive 1 (OXSR1) interaction partners

  1. increased phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter in obesity and identifies a new role for AMP-activated protein kinase in regulating the activity of oxidative stress responsive 1 kinase-related proline-alanine-rich protein kinase

  2. OSR1 (show OSR1 ELISA Kits) is expressed in intestine and partial WNK insensitivity of OSR1 (show OSR1 ELISA Kits) increases intestinal Na( )/H( ) exchanger activity and colonic epithelium Na( ) channel activity

  3. Data indicate that SPAK (show STK39 ELISA Kits) and OSR1 (show OSR1 ELISA Kits) function interdependently in the distal convoluted tubule (DCT (show DCT ELISA Kits)) to positively regulate thiazide-sensitive sodium-chloride cotransporter (show SLC12A3 ELISA Kits), NCC (show SLC12A3 ELISA Kits).

  4. Partial OSR1 (show OSR1 ELISA Kits) deficiency influences Na(+)/H(+) exchanger activity, ROS (show ROS1 ELISA Kits) formation, and migration of dendritic cells.

  5. Results clearly establish that PHAII caused by the WNK4 (show WNK4 ELISA Kits) D561A mutation is dependent on the activation of the WNK-OSR1 (show OSR1 ELISA Kits)/SPAK (show STK39 ELISA Kits)-NCC (show SLC12A3 ELISA Kits) cascade.

  6. Two Ste20-like (show STK25 ELISA Kits) kinases that bind and phosphorylate NKCC1 (show SLC12A2 ELISA Kits): Ste20 (show STK24 ELISA Kits)-related proline-alanine-rich kinase (SPAK (show STK39 ELISA Kits)) and oxidative-stress response 1 (OSR1 (show OSR1 ELISA Kits)), were identified.

  7. In the kidneys, NKCC2 (show SLC12A1 ELISA Kits) but not NCC (show SLC12A3 ELISA Kits) is the main target of OSR1 (show OSR1 ELISA Kits) and the reduced p-NKCC2 (show SLC12A1 ELISA Kits) in KSP-OSR1 (show OSR1 ELISA Kits)(-/-) mice may lead to a Bartter-like syndrome.

  8. phosphorylation states of NCC (show SLC12A3 ELISA Kits) and OSR1 (show OSR1 ELISA Kits)/SPAK (show STK39 ELISA Kits) (Gene: Oxsr1, GeneID: 108737) were increased by low-salt diets and decreased by high-salt diets

  9. OSR1 (show OSR1 ELISA Kits), a kinase closely related to SPAK (show STK39 ELISA Kits), exhibited similar kinase properties and similar functional activation of NKCC1 (show SLC12A2 ELISA Kits) when coexpressed with WNK4 (show WNK4 ELISA Kits).

  10. review: NCC (show SLC12A3 ELISA Kits) in the distal convoluted tubule plays a critical role in NaCl and, indirectly, in K+ homeostasis; regulation by SPAK (show STK39 ELISA Kits)/OSR1 (show OSR1 ELISA Kits) kinases and WNKs.

Pig (Porcine) Oxidative-Stress Responsive 1 (OXSR1) interaction partners

  1. The gene shows 92.8% nucleotide identity and 95.5% amino acid identity with human OSR1 (show OSR1 ELISA Kits).

Oxidative-Stress Responsive 1 (OXSR1) Antigen Profile

Antigen Summary

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

Gene names and symbols associated with OXSR1

  • oxidative-stress responsive 1 (OXSR1) antibody
  • oxidative-stress responsive 1b (oxsr1b) antibody
  • serine/threonine-protein kinase OSR1 (CpipJ_CPIJ015177) antibody
  • serine/threonine-protein kinase OSR1 (Tsp_00299) antibody
  • odd-skipped related 1 (Drosophila) (OSR1) antibody
  • oxidative stress responsive 1 (OXSR1) antibody
  • oxidative-stress responsive 1 (Oxsr1) antibody
  • 2210022N24Rik antibody
  • 2810422B09Rik antibody
  • AI462649 antibody
  • AW209236 antibody
  • mKIAA1101 antibody
  • Osr1 antibody
  • OXSR1 antibody
  • zgc:55494 antibody
  • zgc:77321 antibody

Protein level used designations for OXSR1

serine/threonine-protein kinase OSR1 , oxidative-stress responsive 1 , protein odd-skipped-related 1 , oxidative stress-responsive 1 protein

GENE ID SPECIES
100050017 Equus caballus
394150 Danio rerio
6048779 Culex quinquefasciatus
10901611 Trichinella spiralis
539430 Bos taurus
9943 Homo sapiens
607809 Canis lupus familiaris
316064 Rattus norvegicus
108737 Mus musculus
397618 Sus scrofa
100174028 Pongo abelii
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