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Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 Proteins (OLR1)

OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Antibodies (198) and OLR1 Kits (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OLR1 4973 P78380
OLR1 108078 Q9EQ09
OLR1 140914 O70156
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Top OLR1 Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Cynomolgus His tag 50 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat His tag 50 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$552.20
Details

OLR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
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Mouse (Murine) ,
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Rat (Rattus) , ,
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Top referenced OLR1 Proteins

  1. Human OLR1 Protein expressed in Escherichia coli (E. coli) - ABIN667547 : Kataoka, Kume, Miyamoto, Minami, Moriwaki, Murase, Sawamura, Masaki, Hashimoto, Kita: Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions. in Circulation 1999 (PubMed)
    Show all 2 references for ABIN667547

  2. Cynomolgus OLR1 Protein expressed in Human Cells - ABIN2009921 : Hinagata, Kakutani, Fujii, Naruko, Inoue, Fujita, Mehta, Ueda, Sawamura: Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. in Cardiovascular research 2005 (PubMed)

More Proteins for Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Interaction Partners

Rabbit Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.

  2. LOX (show LOX Proteins) and LOXL2 (show LOXL2 Proteins) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (show LOXL2 Proteins) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (show LOX Proteins), reducing angiogenesis and inflammation, and fibrosis.

  3. Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (show AGT Proteins)-mediated inflammation in endothelial cells

  4. Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.

  5. Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.

  6. LOX-1 expression appears to be closely associated with tissue factor (show F3 Proteins) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Human Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. the current meta-analysis highlighted that variant allele of OLR1 rs11053646 G > C and PCSK9 (show PCSK9 Proteins) rs505151 A > G may contribute to the susceptibility risk of ischemic stroke.

  2. Silencing of LOX-1 gene expression abolished ox-LDL induced effects in cell viability, reactive oxygen species generation and gene expression.

  3. both the 501>C single nucleotide polymorphisms in the LOX1 gene and the serum LOX1 level may be used to predict the development of left ventricular hypertrophy among essential hypertension patients.

  4. rapamycin reduces mTOR (show FRAP1 Proteins) phosphorylation and subsequently inhibit NF-kappaB (show NFKB1 Proteins) activation and suppresses LOX-1, resulting in a reduction in ox-LDL uptake in HUVECs

  5. for our Turkish sample group, LOX-1 30UTR188C/T and K167N polymorphisms may not be involved in susceptibility to GDM [gestational diabetes mellitus ]

  6. Cholesterol depletion triggers the release of LOX-1 in exosomes as a full-length transmembrane isoform and as a truncated ectodomain soluble fragment.

  7. Interaction between Lox-1, C-reactive protein (show CRP Proteins) and oxidized LDL play role in the pathogenesis of atherosclerosis.

  8. OLR1 is a novel molecular link between the proliferative and inflammatory responses of vascular smooth muscle cells.

  9. Ginkgo biloba extract inhibits oxLDL-induced matrix metalloproteinase (show MMP20 Proteins) activation by the modulation of the LOX1-regulated signaling pathway in human umbilical vein endothelial cells.

  10. Data show that the interplay between the two TNF (show TNF Proteins) receptors (TNFR1 (show TNFRSF1A Proteins) and TNFR2 (show TNFRSF1B Proteins)) was apparent in the expression pattern of lectin-type oxidized LDL receptor 1 (LOX-1) in response to TNF-alpha (show TNF Proteins).

Mouse (Murine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. that ox-LDL receptor-1 and PCSK9 (show PCSK9 Proteins) positively influence each other's expression, especially during an inflammatory reaction

  2. LOX1 is implicated in OxLDLinduced oxidative stress of macrophages in atherosclerosis, which in part, involves the regulation of NADPH (show FDXR Proteins) oxidases.

  3. LOX-1 is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Proteins) and -2.

  4. mice with LOX-1 deletion given similar infusion of angiotensin II showed much less rise in blood pressure, and less expression of NADPH oxidase (show NOX1 Proteins), activation of P38 MAPK (show MAPK14 Proteins) and nuclear factor-kappaB, autophagy-related proteins and TLR4 (show TLR4 Proteins) than wild-type mice.

  5. LOX-1 plays an important role in ischemia-induced angiogenesis by 1) Nox2 (show CYBB Proteins)-ROS (show ROS1 Proteins)-NF-kappaB (show NFKB1 Proteins) activation, 2) upregulated expression of adhesion molecules: VCAM-1 (show VCAM1 Proteins) and LOX-1 and 3) promoting macrophage infiltration.

  6. Our findings indicate the novel involvement of LOX-1 in physiological bone homeostasis and inflammatory bone diseases.

  7. LOX-1 activation by oxLDL is an important event that enhances tumor angiogenesis

  8. our results indicate that LPS (show TLR4 Proteins) up-regulates LOX-1, at least in part through activation of the Erk1/2 signaling pathway,thus highlighting a critical role of TLR4 (show TLR4 Proteins)-mediated aberrant LOX-1 signaling in the pathogenesis of atherosclerosis

  9. data indicated that olmesartan may attenuate the impairment of endothelial cell via down-regulation of the increased LOX-1 expression induced by ox-LDL.

  10. findings suggest that LOX-1 participates in angiogenesis in hypertension, which may be related to a state of inflammation.

Cow (Bovine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.

  2. These results imply that the 3' UTR SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.

  3. Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals

  4. In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus

  5. The downregulation of eNOS (show NOS3 Proteins) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (show AKT1 Proteins)-eNOS (show NOS3 Proteins) signaling pathway.

  6. 3'-UTR SNP assoicated with milk composition traits and somatic cell score

  7. Oxidized low-density lipoprotein receptor (show LDLR Proteins) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage

  8. synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (show Vcan Proteins) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1

  9. Upregulates VEGF (show VEGFA Proteins) expression in articular cartilage, at least in part, through activation of PPAR-gamma (show PPARG Proteins).

  10. Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis.

OLR1 Protein Profile

Protein Summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with OLR1

  • oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1)
  • lectin-like oxidized LDL receptor (LOX-1)
  • oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1)
  • CLEC8A protein
  • LOX-1 protein
  • LOX1 protein
  • LOXIN protein
  • Oldlr1 protein
  • Oldr1 protein
  • Olr1 protein
  • PLOX-1 protein
  • Scare1 protein
  • SLOX1 protein
  • SR-EI protein

Protein level used designations for OLR1

oxidised low density lipoprotein (lectin-like) receptor 1 , oxidized low density lipoprotein (lectin-like) receptor 1 , lectin-like oxLDL receptor 1 , lectin-like oxidized LDL receptor 1 , lectin-type oxidized LDL receptor 1 , ox-LDL receptor 1 , oxidized low-density lipoprotein receptor 1 , C-type lectin domain family 8 member A , hLOX-1 , ox LDL receptor 1 , oxidized low-density lipoprotein receptor 1, soluble form , scavenger receptor class E, member 1 , Lectin-like oxidized low-density lipoprotein receptor-1 , lectin-like oxidized low-density lipoprotein receptor , BLOX1 , LOX-1 , bLOX-1 , lectin-like oxidized LDL receptor-1 , oxidized low density lipoprotein receptor 1

GENE ID SPECIES
473362 Pan troglodytes
486694 Canis lupus familiaris
100009322 Oryctolagus cuniculus
4973 Homo sapiens
108078 Mus musculus
140914 Rattus norvegicus
281368 Bos taurus
396724 Sus scrofa
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