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OSBPL10 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 10 Antibodies (46) and many more products for this protein.
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Data indicate that the apoB-100 (show APOB Proteins) secretion phenotype is replicated in HepG2 cells transduced with the ORP10 shRNA lentiviruses.
Single-nucleotide polymorphisms in OSBPL10 is associated with peripheral arterial disease.
Overall, the rs2290532 (D254N) polymorphism in OSBPL10 may predispose individuals to hyper-LDL cholesterolemia.
Analysis of variants in three genes encoding OSBP (show OSBP Proteins) homologues in families with familial low high-density lipoprotein levels or familial combined hyperlipidemia revealed linkage of OSBPL10 single-nucleotide polymorphisms with high triglyceride trait.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene.
oxysterol binding protein-like 10
, oxysterol-binding protein-like protein 10
, oxysterol-binding protein-like protein 10-like
, oxysterol-binding protein-related protein 10-like
, OSBP-related protein 10
, oxysterol-binding protein-related protein 10