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Oxysterol Binding Protein-Like 2 Proteins (OSBPL2)

OSBPL2 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 2 Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OSBPL2 9885 Q9H1P3
OSBPL2 228983 Q8BX94
Rat OSBPL2 OSBPL2 296461  
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Top Oxysterol Binding Protein-Like 2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OSBPL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Oxysterol Binding Protein-Like 2 (OSBPL2) Interaction Partners

Human Oxysterol Binding Protein-Like 2 (OSBPL2) interaction partners

  1. This study and the recent description of another frameshift mutation in a Chinese ADNSHL family identify OSBPL2 as a novel gene for progressive deafness.

  2. Results identified frameshift and missense mutation in OSBPL2 gene in familial and sporadic case of deafness suggesting OSBPL2 as a novel candidate gene for autosomal dominant nonsyndromic hearing loss .

  3. Complexes of human ORP2 and VAPs at endoplasmic reticulum-lipid droplet interfaces regulate the hydrolysis of triglycerides and lipid droplet turnover.

  4. ORP2 as a novel regulator of cellular sterol homeostasis and intracellular membrane trafficking.

  5. Results identify ORP2 as a sterol receptor present on LD and provide evidence for its role in the regulation of neutral lipid metabolism, possibly as a factor that integrates the cellular metabolism of triglycerides with that of cholesterol.

Mouse (Murine) Oxysterol Binding Protein-Like 2 (OSBPL2) interaction partners

  1. The regulation of OSBPL2 by Mir96 was investigated in Mir96 mutant mice.

Oxysterol Binding Protein-Like 2 (OSBPL2) Protein Profile

Protein Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Gene names and symbols associated with OSBPL2

  • oxysterol binding protein-like 2b (osbpl2b)
  • oxysterol binding protein-like 2 (osbpl2)
  • oxysterol binding protein-like 2 (OSBPL2)
  • oxysterol binding protein-like 2 (Osbpl2)
  • C130070J12Rik protein
  • MGC52852 protein
  • MGC75824 protein
  • MGC130835 protein
  • mKIAA0772 protein
  • ORP-2 protein
  • Orp2 protein
  • Osbpl1a protein
  • OSBPL2 protein
  • wu:fi36a04 protein
  • zgc:55948 protein

Protein level used designations for OSBPL2

oxysterol binding protein-like 1A , oxysterol binding protein-like 2 , oxysterol-binding protein-related protein 2 , oxysterol-binding protein-like protein 2 , oxysterol-binding protein-related protein 2-like , OSBP-related protein 2 , oxysterol-binding protein-like 2

GENE ID SPECIES
334206 Danio rerio
380004 Xenopus laevis
403099 Xenopus (Silurana) tropicalis
419227 Gallus gallus
477283 Canis lupus familiaris
505328 Bos taurus
699811 Macaca mulatta
737641 Pan troglodytes
100051127 Equus caballus
100388542 Callithrix jacchus
100455026 Pongo abelii
100470101 Ailuropoda melanoleuca
100543334 Meleagris gallopavo
100558938 Anolis carolinensis
100605090 Nomascus leucogenys
9885 Homo sapiens
228983 Mus musculus
296461 Rattus norvegicus
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