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anti-Oxysterol Binding Protein-Like 8 (OSBPL8) Antibodies

OSBPL8 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Additionally we are shipping Oxysterol Binding Protein-Like 8 Kits (4) and Oxysterol Binding Protein-Like 8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OSBPL8 314824  
OSBPL8 114882 Q9BZF1
OSBPL8 237542  
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Top anti-Oxysterol Binding Protein-Like 8 Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-OSBPL8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OSBPL8 Antibody Titration: 0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate Host: Rabbit   Target Name: OSBPL8   Sample Tissue: OVCAR-3  Antibody Dilution: 1.0 µg/mL OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB OSBPL8 monoclonal antibody (M02), clone 4H6. Western Blot analysis of OSBPL8 expression in Jurkat. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB OSBPL8 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB OSBPL8 monoclonal antibody (M02), clone 4H6. Western Blot analysis of OSBPL8 expression in Jurkat . Detection limit for recombinant GST tagged OSBPL8 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of OSBPL8 expression in transfected 293T cell line by OSBPL8 MaxPab polyclonal antibody.Lane 1: OSBPL8 transfected lysate(93.17 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details

OSBPL8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


Top referenced anti-Oxysterol Binding Protein-Like 8 Antibodies

  1. Cow (Bovine) Polyclonal OSBPL8 Primary Antibody for WB - ABIN2781875 : Yan, Mäyränpää, Wong, Perttilä, Lehto, Jauhiainen, Kovanen, Ehnholm, Brown, Olkkonen: OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Oxysterol Binding Protein-Like 8 Interaction Partners

Human Oxysterol Binding Protein-Like 8 (OSBPL8) interaction partners

  1. ORP5 (show OSBPL5 Antibodies) and ORP8 could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 (show SACM1L Antibodies) for degradation and PS from the ER to the PM.

  2. role of ORP8 in Fas (show FAS Antibodies) translocation to the plasma membrane and its down-regulation by miR (show MLXIP Antibodies)-143 offer a putative mechanistic explanation for HCC (show FAM126A Antibodies) resistance to apoptosis

  3. Data indicate that miR (show MLXIP Antibodies)-143 impairs insulin (show INS Antibodies) action via downregulation of oxysterol-binding protein-related protein 8 (ORP8).

  4. ORP8 overexpression resulted in reduced expression of the aP2 (show GTF3A Antibodies) mRNA, while down-regulation of adiponectin (show ADIPOQ Antibodies) and aP2 (show GTF3A Antibodies) was observed in ORP11 (show OSBPL11 Antibodies) silenced cells. ORP8 overexpression or silencing of ORP11 (show OSBPL11 Antibodies) markedly decreased cellular triglyceride storage.

  5. results reveal that ORP8 has the capacity to modulate lipid homeostasis and SREBP activity, probably through an indirect mechanism, and provide clues of an entirely new mode of ORP action

  6. Data identify ORP8 as a negative regulator of ABCA1 (show ABCA1 Antibodies) expression and macrophage cholesterol efflux. ORP8 may, thus, modulate the development of atherosclerosis.

Mouse (Murine) Oxysterol Binding Protein-Like 8 (OSBPL8) interaction partners

  1. Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor (show LDLR Antibodies) knockout mice.

  2. Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

  3. aspects of ORP8 function in macrophages not directly involving lipid metabolism, but rather associated with nuclear functions, microtubule organization, and migration capacity

Oxysterol Binding Protein-Like 8 (OSBPL8) Antigen Profile

Protein Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with OSBPL8

  • oxysterol binding protein-like 8 (Osbpl8) antibody
  • oxysterol binding protein-like 8 (OSBPL8) antibody
  • oxysterol binding protein-like 8 (osbpl8) antibody
  • AA536976 antibody
  • AA536995 antibody
  • C730029P18Rik antibody
  • D330025H14Rik antibody
  • DKFZp469P0923 antibody
  • MST120 antibody
  • MSTP120 antibody
  • ORP-8 antibody
  • ORP8 antibody
  • OSBP10 antibody
  • RGD1561474 antibody

Protein level used designations for OSBPL8

oxysterol-binding protein-related protein 8 , oxysterol binding protein-like 8 , oxysterol-binding protein-like protein 8 , oxysterol-binding protein-related protein 8-like , ORP-8 , OSBP-related protein 8

GENE ID SPECIES
314824 Rattus norvegicus
417866 Gallus gallus
446929 Xenopus laevis
452085 Pan troglodytes
693338 Macaca mulatta
100018363 Monodelphis domestica
100059086 Equus caballus
100145444 Xenopus (Silurana) tropicalis
100172591 Pongo abelii
100175952 Ciona intestinalis
100218984 Taeniopygia guttata
100356792 Oryctolagus cuniculus
100484438 Ailuropoda melanoleuca
100525288 Sus scrofa
100566303 Anolis carolinensis
100595122 Nomascus leucogenys
100409878 Callithrix jacchus
114882 Homo sapiens
475408 Canis lupus familiaris
533350 Bos taurus
237542 Mus musculus
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