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PAGE4 is a member of the GAGE family. Additionally we are shipping P Antigen Family, Member 4 (Prostate Associated) Antibodies (23) and many more products for this protein.
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phosphorylation of PAGE4 leads to conformational shifts
PAGE4, a regulator of c-Jun (show JUN Proteins) transactivation, is phosphorylated by homeodomain-interacting protein kinase 1 (show HIPK1 Proteins).
Data suggest that disrupting prostate-associated gene 4 (PAGE4)/c-Jun (show JUN Proteins) interaction using small molecules could be a novel strategy to treat prostate cancer.
Dysregulation of epithelial PAGE4 modulates AR signaling.
PAGE4 is a highly intrinsically disordered protein with an anti-apoptotic function
PAGE4 mRNA is expressed only in the cytoplasm of epithelial cells of normal and prostate-cancer specimens
This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE\\/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens.
P antigen family member 4
, g antigen family C member 1
, prostate-associated gene protein 4