P21 Protein (Cdc42/Rac)-Activated Kinase 7 Proteins (PAK7)

The protein encoded by PAK7 is a member of the PAK family of Ser/Thr protein kinases. Additionally we are shipping PAK7 Antibodies (95) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PAK7 57144 Q9P286
PAK7 241656 Q8C015
PAK7 311450 D4A280
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Top PAK7 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 10 μg Log in to see 12 to 15 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
Insect Cells Human GST tag   10 μg Log in to see 3 to 4 Days
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 2 to 3 Days

PAK7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Interaction Partners

Human P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. Data suggest expression of ECAD (E-cadherin (show CDH1 Proteins)) in bladder cancer cell lines correlates with presence of intercellular junctions and level of PAK5 (show PAK6 Proteins) (p21 (show CDKN1A Proteins)-activated kinase PAK5 (show PAK6 Proteins) protein) expression; endogenous PAK5 (show PAK6 Proteins) is localized to intercellular junctions and interacts with ECAD (show CDH1 Proteins); depletion of PAK5 (show PAK6 Proteins) expression reduces integrity of intercellular junctions; PAK5 (show PAK6 Proteins) mRNA levels are reduced in bladder cancer compared with normal controls.

  2. model suggests PAK5 self-association interferes with AID binding to the catalytic domain, thus maintaining its high activity.

  3. PAK7 expression is significantly downregulated in human masticatory mucosa during wound healing

  4. PAK7 is overexpressed in human esophageal squamous cell cancer samples and correlated with lymph node metastasis.

  5. E47 (show TCF3 Proteins) is a novel substrate of PAK5 (show PAK6 Proteins), and PAK5 (show PAK6 Proteins)-mediated phosphorylation of E47 (show TCF3 Proteins) promotes epithelial-mesenchymal transition and metastasis of colon cancer.

  6. Aurora-A induced PAK7 expression in esophageal cancer cells.

  7. results suggest that the inhibition of PAK5 by RNA interference might efficiently suppress tumor development of glioma cells with PAK5 high expression.

  8. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma.

  9. PAK7 promotes cell proliferation and tumorigenesis

  10. It inhibits glioma cell migration and invasion potentially through the PAK5 (show PAK6 Proteins)-Egr1 (show EGR1 Proteins)-MMP2 (show MMP2 Proteins) signaling pathway.

Mouse (Murine) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) interaction partners

  1. PAK-7 p21-activated kinase 5 knockout mice are more sensitive to the stimulant effects of amphetamine

  2. functional deficits in PAK5, PAK6 (show PAK6 Proteins) and PAK5/PAK6 (show PAK6 Proteins) knockout mice

  3. PAK 5 is involved in formalin-induced inflammatory nociception through regulation of MAPK-induced c-Fos-activation and formalin-specific transient receptor potential-channels.

  4. These results implicate Pak5 in Pacsin1 (show PACSIN1 Proteins)- and Synaptojanin1-mediated synaptic vesicle trafficking.

  5. PAK5 may provide a molecular rationale for late-stage complications in diabetes.

  6. Our results indicate that Pak5 and Pak6 (show PAK6 Proteins) together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

PAK7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with PAK7

  • p21 protein (Cdc42/Rac)-activated kinase 7 (PAK7)
  • p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7)
  • 2900083L08Rik protein
  • 6430627N20 protein
  • PAK-5 protein
  • PAK-7 protein
  • Pak5 protein

Protein level used designations for PAK7

PAK-5 , PAK-7 , p21(CDKN1A)-activated kinase 7 , p21-activated kinase 5 , p21-activated kinase 7 , p21CDKN1A-activated kinase 7 , protein kinase PAK5 , serine/threonine-protein kinase PAK 7 , serine/threonine-protein kinase PAK7 , p21 (CDKN1A)-activated kinase 7

57144 Homo sapiens
241656 Mus musculus
311450 Rattus norvegicus
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