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PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) ELISA Kits

PAXIP1 is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. Additionally we are shipping PAXIP1 Antibodies (21) and PAXIP1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PAXIP1 PAXIP1 22976 Q6ZW49
Anti-Mouse PAXIP1 PAXIP1 55982 Q6NZQ4
Anti-Rat PAXIP1 PAXIP1 311944  
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More ELISA Kits for PAXIP1 Interaction Partners

Human PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) interaction partners

  1. PTIP promotes double-strand break repair through a direct role in homologous recombination.

  2. PPM1B (show PPM1B ELISA Kits) can dephosphorylate the Pax2 (show PAX2 ELISA Kits) activation domain and displace the adaptor protein PTIP, thus inhibiting H3K4 methylation and gene activation.

  3. uncovered a nuclease (show DCLRE1C ELISA Kits), Artemis (show DCLRE1C ELISA Kits), as a PTIP-binding protein

  4. PITX2 (show PITX2 ELISA Kits) and PTIP co-occupy the promoter of the PITX2 (show PITX2 ELISA Kits)'s transcriptional target.

  5. Polyglutamine expansion AR sequesters PTIP to attenuate DNA repair and increase genomic instability.

  6. a new clue to identify the role of PTIP in DNA damage pathway

  7. PTIP controls expression of P (show PPARG ELISA Kits)PARgamma and C/ (show CEBPA ELISA Kits)EBPalpha, the two principal adipogenic transcription factors, and is therefore required for adipogenesis.

  8. PTIP (PAXIP1) is a strong inhibitor of the trans-activation activities of Pax2A and Pax2B on the glucagon (show GCG ELISA Kits) gene promoter and p8 binding to PTIP prevents inhibition of this promoter.

  9. identified tandem BRCT (BRCA1 carboxyl-terminal) domains in PTIP and in BRCA1 as phosphoserine- or phosphothreonine-specific binding modules that recognize substrates phosphorylated by the kinases ATM and ATR in response to gamma-irradiation

  10. hPTIP (PAXIP1) shows increased association with 53BP1 (show TP53BP1 ELISA Kits) in response to ionizing radiation but not in response to other DNA-damaging agents.

Xenopus laevis PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) interaction partners

  1. Immunodepletion of PTIP/Swift from Xenopus extracts prevented efficient proliferating cell nuclear antigen (show PCNA ELISA Kits) ubiquitination and polymerase eta (show POLH ELISA Kits) recruitment to chromatin during replicative stress

Mouse (Murine) PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) interaction partners

  1. a PTIP-PA1 subcomplex functions independently from the MLL3/MLL4 complex to mediate transcription during CSR

  2. Study concludes that 53BP1 (show TP53BP1 ELISA Kits) promotes productive class switch recombination and suppresses mutagenic DNA repair through distinct phosphodependent interactions with RIF1 (show RIF1 ELISA Kits) and PTIP.

  3. Polyglutamine expansion AR sequesters PTIP to attenuate DNA repair and increase genomic instability.

  4. PAXIP1 controls distinct transcriptional programs during DP differentiation necessary for Tcra locus accessibility, licensing mature thymocytes for trafficking and natural killer T cell development.

  5. PTIP plays an important role in the DNA repair process associated with the development of mature spermatozoa.

  6. PTIP stabilizes the Pax5 (show PAX5 ELISA Kits) DNA interactions that promote chromatin looping and regulate transcriptional responses needed for class switch recombination.

  7. Data show that loss of PTIP resulting in subtle changes in gene expression patterns and lower H3K4 methylation.

  8. PTIP accumulation at double stranded breaks contributes to class switch recombination and genome stability independently of Igh switch transcription

  9. PTIP is an essential element of the cell proliferation machinery, perhaps by functioning in the DNA repair pathways

  10. Pax (show PXN ELISA Kits) transactivation domain-interacting protein is required for the urine concentration mechanism by modulating arginine vasopressin receptor 2 (show AVPR2 ELISA Kits) and AQP2 (show AQP2 ELISA Kits) expression in the inner medulla.

PAXIP1 Antigen Profile

Antigen Summary

This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.

Gene names and symbols associated with PAXIP1

  • PAX interacting (with transcription-activation domain) protein 1 (PAXIP1) antibody
  • PAX interacting (with transcription-activation domain) protein 1 (paxip1) antibody
  • pax interacting (with transcription-activation domain) protein 1 (paxip1) antibody
  • PAX interacting (with transcription-activation domain) protein 1 (Paxip1) antibody
  • cagf28 antibody
  • cagf29 antibody
  • D5Ertd149e antibody
  • k14 antibody
  • pacip1 antibody
  • paxip1l antibody
  • ptip antibody
  • tnrc2 antibody
  • wu:fa04b06 antibody
  • zgc:92593 antibody

Protein level used designations for PAXIP1

PAX transcription activation domain interacting protein 1 like , PAX-interacting protein 1 , protein encoded by CAG trinucleotide repeats , PAX transactivation activation domain-interacting protein , fa04b06 , SMAD wing for transcriptional activation , Swift , protein Swift , PAX interacting protein 1

GENE ID SPECIES
22976 Homo sapiens
449658 Danio rerio
398236 Xenopus laevis
482813 Canis lupus familiaris
513213 Bos taurus
55982 Mus musculus
311944 Rattus norvegicus
463836 Pan troglodytes
100455902 Pongo abelii
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