You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-PC4 and SFRS1 Interacting Protein 1 (PSIP1) Antibodies

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Additionally we are shipping PC4 and SFRS1 Interacting Protein 1 Proteins (10) and PC4 and SFRS1 Interacting Protein 1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PSIP1 11168 O75475
PSIP1 101739 Q99JF8
PSIP1 313323 Q812D1
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-PC4 and SFRS1 Interacting Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PSIP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate Human Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PSIP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-PSIP1 AntibodyTitration: 5 µg/mL  Positive Control: Jurkat Whole Cell  PSIP1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PSIP1 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunofluorescence analysis of NIH/3T3 cells using PSIP1 mouse mAb (green) . Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. 100 μL Log in to see 3 to 4 Days
$442.20
Details
Human Mouse Un-conjugated BI, IF, WB Western blot analysis of LEDGF on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2) (left). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-human LEDGF antibody. Immunofluorescent staining of SK-N-SH cells (Human neuroblastoma, ATCC HTB-11) (right). Cells were seeded in collagen coated 384-well imaging microplates at ~ 8,000 cells per well. After overnight incubation, cells were stained using the Triton-X 100 fix/perm protocol and the mouse anti-human LEDGF antibody. The second step reagent was Alexa Fluor® 488 goat anti mouse Ig (Invitrogen) (pseudo-colored green) and counter-stained with Hoechst 33342 (pseudo-colored blue). The images were captured on a BD Pathway™ 855 or 435 Bioimager system using a 20x objective and merged using BD Attovision™ software. This antibody also stained SH-SY5Y (Human neuroblastoma, ATCC CRL-2266), C6 (Rat glioma, ATCC CCL-107), U-87 MG (Human glioblastoma cells, ATCC HTB-14) and U-373 cells (Human glioblastoma cells, ATCC HTB-17, discontinued) using both the Triton-X 100 and methanol fix/perm protocols. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to PSIP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged PSIP1 is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

PSIP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, ,
,
, , , , ,
Mouse (Murine) ,


,
Rat (Rattus) ,
,
,
,

Top referenced anti-PC4 and SFRS1 Interacting Protein 1 Antibodies

  1. Human Monoclonal PSIP1 Primary Antibody for BI, IF - ABIN968640 : Cherepanov, Maertens, Proost, Devreese, Van Beeumen, Engelborghs, De Clercq, Debyser: HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN968640

  2. Human Monoclonal PSIP1 Primary Antibody for EIA, IF - ABIN1108769 : Shun, Botbol, Li, Di Nunzio, Daigle, Yan, Lieberman, Lavigne, Engelman: Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity. in Journal of virology 2008 (PubMed)
    Show all 2 references for ABIN1108769

  3. Chicken Polyclonal PSIP1 Primary Antibody for WB - ABIN2775928 : Llano, Vanegas, Fregoso, Saenz, Chung, Peretz, Poeschla: LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. in Journal of virology 2004 (PubMed)

  4. Human Monoclonal PSIP1 Primary Antibody for IHC (p), ELISA - ABIN564851 : Shun, Raghavendra, Vandegraaff, Daigle, Hughes, Kellam, Cherepanov, Engelman: LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. in Genes & development 2007 (PubMed)

  5. Cow (Bovine) Polyclonal PSIP1 Primary Antibody for WB - ABIN2775996 : Vandegraaff, Devroe, Turlure, Silver, Engelman et al.: Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration... in Virology 2006 (PubMed)

  6. Cow (Bovine) Polyclonal PSIP1 Primary Antibody for WB - ABIN2775927 : Janssen, Schiffmann, Birod, Maier, Wobst, Geisslinger, Grösch: p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells. in Biochemical and biophysical research communications 2007 (PubMed)

More Antibodies against PC4 and SFRS1 Interacting Protein 1 Interaction Partners

Human PC4 and SFRS1 Interacting Protein 1 (PSIP1) interaction partners

  1. LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced (show SQSTM1 Antibodies) Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 (show PDIA3 Antibodies) in Prostate Cancer

  2. common LEDGF/p75 interaction interface shared by JPO2 (show CDCA7L Antibodies), PogZ (show POGZ Antibodies), MLL1, IWS1 and HIV IN

  3. Results show that these antibodies are highly specific for dense fine speckles 70 protein DFS70/LEDGFp75 and do not target methyl CpG binding protein 2 (MeCP2 (show MECP2 Antibodies)).

  4. LEDGF/p75 interacts with splicing factors, contributes to exon choice, and directs HIV-1 integration to transcription units that are highly spliced.

  5. Together, these results provide evidence for an Integrase/Pol mediated uptake of LEDGF/p75 in HIV-1 viral particles and a specific cleavage by HIV protease.

  6. Altogether, these results indicate that a complex containing LEDGF/p75, Iws1, and Spt6 (show SUPT6H Antibodies) participates in regulating postintegration steps of HIV latency.

  7. LEDGF and 44 other novel putative nuclear targets of human thioredoxin 1 have been identified.

  8. Results of the present work reinforce the association of PSIP1 gene and rs61744944 single nucleotide polymorphism with HIV-1 infection long-term nonprogressors status.

  9. Data show that the same site on integrase-binding domain (IBD) of lens epithelium-derived growth factor (LEDGF) is involved in binding to MLL (show MLL Antibodies) protein and HIV-IN (integrase), indicating an approach to target LEDGF in both leukemia and HIV infection.

  10. Authors identified an additional LEDGF/p75-MLL (show MLL Antibodies) interface, which overlaps with the binding site of known LEDGF/p75 interactors-HIV-1 integrase, PogZ (show POGZ Antibodies), and JPO2 (show CDCA7L Antibodies).

Mouse (Murine) PC4 and SFRS1 Interacting Protein 1 (PSIP1) interaction partners

  1. The role of Psip1 in cardiac development

  2. conclude that small peptides disrupting the LEDGF/p75-MLL (show MLL Antibodies) interface have selective anti-leukemic activity providing a direct rationale for the design of small molecule inhibitors targeting this interaction

  3. Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration.

  4. Alcohol (ADH (show AVP Antibodies)) and ALDH (show ALDH3A1 Antibodies) dehydrogenases are implicated in cellular detoxification and conversion of vitamin A to RA. Lens epithelium-derived growth factor provides cellular protection against stress by transactivating stress-associated genes.

  5. Results suggest that TNF-alpha (show TNF Antibodies) elevates the expression of lens epithelium-derived growth factor (LEDGF) and that LEDGF is one of the transactivators of gamma-glutamylcysteine synthetase heavy subunit (show GCLC Antibodies) gene.

  6. These suggest a role for Psip1 in the control of Homeobox (show PRRX1 Antibodies) expression and may also explain why PSIP1 (LEDGF) is found as a fusion partner with NUP98 (show NUP98 Antibodies) in myeloid leukemias.

  7. some DFS70-positive sera have antibodies that recognize antigens of the lens

PC4 and SFRS1 Interacting Protein 1 (PSIP1) Antigen Profile

Protein Summary

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity).

Gene names and symbols associated with PSIP1

  • PC4 and SFRS1 interacting protein 1 (psip1) antibody
  • PC4 and SFRS1 interacting protein 1 (PSIP1) antibody
  • PC4 and SFRS1 interacting protein 1 (LOC100230181) antibody
  • PC4 and SFRS1 interacting protein 1 (LOC100339871) antibody
  • LEDGF/p75 transcription factor-like (psip1) antibody
  • PC4 and SFRS1 interacting protein 1 (Psip1) antibody
  • AA408851 antibody
  • AU015605 antibody
  • Dfs70 antibody
  • im:7149861 antibody
  • Ledgf antibody
  • LEDGF/p75 antibody
  • Ledgfa antibody
  • Ledgfb antibody
  • p52 antibody
  • p75 antibody
  • PAIP antibody
  • PSIP1 antibody
  • Psip2 antibody
  • SBP75 antibody
  • zgc:109898 antibody

Protein level used designations for PSIP1

PC4 and SFRS1 interacting protein 1 , LEDGF/p75 , PC4 and SFRS1-interacting protein , PC4 and SFRS1-interacting protein-like protein , Lens epithelium-derived growth factor , PC4 and SFRS1-interacting protein-like , putative LEDGF/p75 transcription factor , lens epithelium-derived growth factor , CLL-associated antigen KW-7 , DFS 70 , dense fine speckles 70 kDa protein , transcriptional coactivator p52/p75 , transcriptional coactivator p75/p52 , PC4 and SFRS1 interacting protein 2 , dense fine speckles 70 , mLEDGF , supercoiled DNA binding protein 75 , lens epithelium derived growth factor p75 , transcription coactivator p75

GENE ID SPECIES
398545 Xenopus laevis
465001 Pan troglodytes
553760 Danio rerio
100016299 Monodelphis domestica
100034217 Equus caballus
100145476 Xenopus (Silurana) tropicalis
100195391 Salmo salar
100230181 Taeniopygia guttata
100233239 Ovis aries
100339871 Oryctolagus cuniculus
100401055 Callithrix jacchus
100584230 Nomascus leucogenys
734236 Xenopus laevis
431605 Gallus gallus
11168 Homo sapiens
474712 Canis lupus familiaris
282011 Bos taurus
101739 Mus musculus
313323 Rattus norvegicus
493969 Felis catus
Selected quality suppliers for anti-PC4 and SFRS1 Interacting Protein 1 (PSIP1) Antibodies
Did you look for something else?