anti-PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) Antibodies

PDS5B encodes a protein that interacts with the conserved protein complex termed cohesion. Additionally we are shipping PDS5B Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDS5B 23047 Q9NTI5
PDS5B 100710 Q4VA53
PDS5B 304218  
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Top anti-PDS5B Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PDS5B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: Pds5B Antibody [ABIN152174] - Detection of Human and Mouse Pds5B by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB in A, 1 mg for IP in B, 1/4 of IP reaction loaded), 293T (T, 50 mcg for WB) and NIH3T3 (M, 50 mcg for WB) cells. Antibodies: Affinity purified rabbit anti- Pds5B antibody ABIN152174  used in WB at 0.04 mcg/ml (A) or 0.1 mcg/ml (B) and for IP at 3 mcg/mg lysate (B). Pds5B was also immunoprecipitated using rabbit anti- Pds5B antibody ABIN152173 at 3 mcg/mg lysate. Detection: Chemiluminescence with exposure times of 10 seconds and 3 minutes (A) and 10 seconds (B). Western Blot and Immunoprecipitation: Pds5B Antibody [ABIN152174] - Detection of Human and Mouse Pds5B by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB in A, 1 mg for IP in B, 1/4 of IP reaction loaded), 293T (T, 50 mcg for WB) and NIH3T3 (M, 50 mcg for WB) cells. Antibodies: Affinity purified rabbit anti- Pds5B antibody ABIN152174  used in WB at 0.04 mcg/ml (A) or 0.1 mcg/ml (B) and for IP at 3 mcg/mg lysate (B). Pds5B was also immunoprecipitated using rabbit anti- Pds5B antibody ABIN152173 at 3 mcg/mg lysate. Detection: Chemiluminescence with exposure times of 10 seconds and 3 minutes (A) and 10 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot: APRIN Antibody [NBP2-15436] - Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE; antibody diluted at 1:1000. Western Blot: APRIN Antibody [NBP2-15436] - Sample (30 ug of whole cell lysate) A: Raji 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 6 to 8 Days
$285.71
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: APRIN Antibody [NBP1-90121] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: APRIN Antibody [NBP1-90121] - Staining of human kidney shows strong nuclear positivity in cells in tubules and cells in glomeruli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: APRIN Antibody [NBP1-90122] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Immunocytochemistry/Immunofluorescence: APRIN Antibody [NBP1-90122] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB PDS5B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 16 Days
$275.00
Details

PDS5B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,


Rat (Rattus)


Top referenced anti-PDS5B Antibodies

  1. Cow (Bovine) Polyclonal PDS5B Primary Antibody for WB - ABIN2787631 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

  2. Human Polyclonal PDS5B Primary Antibody for ICC, IF - ABIN152174 : Brough, Bajrami, Vatcheva, Natrajan, Reis-Filho, Lord, Ashworth: APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer. in The EMBO journal 2012 (PubMed)

More Antibodies against PDS5B Interaction Partners

Human PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) interaction partners

  1. Pds5 stabilizes a transient, open state of cohesin to promote its release from chromosomes.

  2. APRIN expression levels correlate with a better survival in ovarian cancer patients and that APRIN depletion sensitizes cells to the PARP (show COL11A2 Antibodies) inhibitor Olaparib in xenografted zebrafish.

  3. Frameshift mutations of SGOL1 and PDS5B and the loss of their expression may be a feature of gastric and colorectal cancers with high microsatellite instability.

  4. Here, the authors use proteomic profiling to identify APRIN (PDS5B), a cohesion-associated protein, as a BRCA2-associated protein.

  5. Loss of a cohesin-linked suppressor APRIN (Pds5b) disrupts stem cell programs in embryonal carcinoma.

  6. AS3 is a mediator of the proliferative arrest in the normal rat prostate in situ and that its expression is androgen-induced (AS3 protein)

  7. The results of this study indicate that the aberrant expression of AS3 may be involved in the tumorigenesis of esophagus and is responsible for the male predominance of ESCC.

  8. identified a functional missense mutation (R1292Q) in the PDS5B DNA-binding domain in a family with Cornelia de Lange syndrome, in which affected individuals also develop megacolon

  9. Pard-3 and AS3 genes are mutationally inactivated in prostate cancer cells.

Mouse (Murine) PDS5, Regulator of Cohesion Maintenance, Homolog B (S. Cerevisiae) (PDS5B) interaction partners

  1. findings demonstrate that Her2+/+ mice, similar to Pds5b-/- mice, are embryonic lethal and confirm the necessity for Pds5b in embryonic development

  2. reduced accumulation of Aurora B (show AURKC Antibodies) at the inner centromere region in cells lacking Pds5B impairs its error correction function, promoting chromosome mis (show AMH Antibodies)-segregation and aneuploidy

  3. demonstrates that overexpression of APRIN inhibits differentiation and proliferation and promotes apoptosis in P19 (show CDKN2D Antibodies) embryonal carcinoma cells.

  4. A paper used gene targeting in mice to demonstrate the function of PDS5B in embryonic development.

  5. APRIN, in addition to its Pds5 similarity, has the features and localization of a hormone-induced chromatin regulator.

  6. While Pds5A(-/-) and Pds5B(-/-) mice die at birth, embryos harboring 3 mutant Pds5 alleles die between E11.5 and E12.5 most likely of heart failure, indicating that total Pds5 gene dosage is critical for normal development.

PDS5B Antigen Profile

Protein Summary

This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.

Gene names and symbols associated with PDS5B

  • PDS5, regulator of cohesion maintenance, homolog B (pds5b-a) antibody
  • PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) (PDS5B) antibody
  • PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) (Pds5b) antibody
  • AI646570 antibody
  • Aprin antibody
  • AS3 antibody
  • AW212954 antibody
  • CG008 antibody
  • mKIAA0979 antibody
  • pds5b antibody

Protein level used designations for PDS5B

androgen-induced proliferation inhibitor A , sister chromatid cohesion protein PDS5 homolog B-A , sister chromatid cohesion protein Pds5B , androgen induced inhibitor of proliferation , androgen-induced proliferation inhibitor , androgen-induced prostate proliferative shutoff-associated protein AS3 , androgen-induced shutoff 3 , sister chromatid cohesion protein PDS5 homolog B , androgen-induced prostate proliferative shutoff associated protein AS3 , androgen-induced prostate proliferative shutoff associated protein

GENE ID SPECIES
734718 Xenopus laevis
23047 Homo sapiens
418910 Gallus gallus
100710 Mus musculus
304218 Rattus norvegicus
486014 Canis lupus familiaris
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