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Plays a role in the regulation of cell morphology and cytoskeletal organization. Additionally we are shipping and many more products for this protein.
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PDZD8 is not absolutely necessary for HIV-1 infection.
The PDZD8 coiled-coil domain is sufficient for HIV-1 capsid binding, but other parts of the protein, including the PDZ domain (show INADL Antibodies), are apparently required for stabilizing the capsid and supporting HIV-1 infection.
PDZD8 is a novel moesin (show MSN Antibodies)-interacting protein that suppresses infection by herpes simplex virus type 1.
A mutant of PDZD8 lacking the coiled-coil domain in its Gag-interacting region failed to bind Gag and promote HIV-1 infection.
Plays a role in the regulation of cell morphology and cytoskeletal organization. May inhibit herpes simplex virus 1 infection at an early stage. May promote retroviral infection.
PDZ domain-containing protein 8
, PDZ domain containing 8
, PDZ domain-containing protein 8-like
, sarcoma antigen NY-SAR-104
, sarcoma antigen NY-SAR-84
, sarcoma antigen NY-SAR-84/NY-SAR-104