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anti-PDZ and LIM Domain 2 (Mystique) (PDLIM2) Antibodies

PDLIM2 encodes a member of the ALP subfamily of PDZ-LIM domain proteins. Additionally we are shipping PDLIM2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDLIM2 213019 Q8R1G6
PDLIM2 290354 Q6AYD6
PDLIM2 64236 Q96JY6
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Top anti-PDLIM2 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC210022 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDLIM2 antibody (ABIN2454465), and then analyzed by flow cytometry. Anti-PDLIM2 mouse monoclonal antibody (ABIN2454465) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454448) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC210022 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDLIM2 antibody (ABIN2454496), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454447) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PDLIM2 mouse monoclonal antibody (ABIN2454449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDLIM2 (RC210022). Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-PDLIM2 mouse monoclonal antibody. (ABIN2454449) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. Flow cytometric Analysis of Jurkat cells, using anti-PDLIM2 antibody (ABIN2454554), (Red), compared to a nonspecific negative control antibody, (Blue). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC210022 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDLIM2 antibody (ABIN2454450), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Cow Goat Un-conjugated EIA, WB Staining of Mouse Lung lysate using PDLIM2 Antibody Cat.-No AP32071PU-N at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PDLIM2 expression in transfected 293T cell line by PDLIM2 MaxPab polyclonal antibody.Lane 1: PDLIM2 transfected lysate(38.72 KDa).Lane 2: Non-transfected lysate. PDLIM2 MaxPab polyclonal antibody. Western Blot analysis of PDLIM2 expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

PDLIM2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Human ,
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Top referenced anti-PDLIM2 Antibodies

  1. Human Polyclonal PDLIM2 Primary Antibody for WB - ABIN528596 : Zhao, Yasunaga, Satou, Nakao, Takahashi, Fujii, Matsuoka: Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. in Blood 2009 (PubMed)

More Antibodies against PDLIM2 Interaction Partners

Mouse (Murine) PDZ and LIM Domain 2 (Mystique) (PDLIM2) interaction partners

  1. Deficiency in PDLIM2 resulted in the accumulation of STAT3 (show STAT3 Antibodies) in the nucleus, enhanced the extent of TH17 cell differentiation, and exacerbated granuloma formation.

  2. Pdlim2 is a novel actin-regulating protein of podocyte foot processes that may have a role in the pathogenesis of glomerular diseases.

  3. OPN (show SPP1 Antibodies) was necessary for PDLIM2 serine phosphorylation and STAT1 (show STAT1 Antibodies) ubiquitination in bone marrow macrophages.

  4. PDLIM2 expression was sufficient to suppress in vitro anchorage-independent growth and in vivo tumor formation of colon cancer. PDLIM2 repression involves promoter methylation.

  5. Knockdown of Mystique 2 with small interfering RNA abrogated both adhesion and migration in MCF10A and MCF-7 cells

  6. SLIM is a novel ubiquitin E3 ligase whose targets include STAT (show STAT1 Antibodies) proteins.

  7. PDLIM2 deficiency resulted in larger amounts of nuclear p65 (show NFkBP65 Antibodies), defective p65 (show NFkBP65 Antibodies) ubiquitination and augmented production of proinflammatory cytokines in response to innate stimuli

  8. Stat-interacting LIM protein as the critical Stat (show STAT1 Antibodies) ubiquitin E3 ligase involved in osteopontin (show SPP1 Antibodies) regulation of Stat1 (show STAT1 Antibodies).

  9. Suppression of PDLIM2 expression resulted in decreased cell adhesion, increased NF-kappaB (show NFKB1 Antibodies) transcription reporter activity, and increased LPS (show TLR4 Antibodies)-induced TNF-alpha (show TNF Antibodies) production.

Human PDZ and LIM Domain 2 (Mystique) (PDLIM2) interaction partners

  1. The suppression of PDLIM2 expression significantly reduced cell proliferation, cell growth and neoplasm invasiveness in prostate cancer cells.

  2. epigenetic repression of PDLIM2 can be reversed by 5-aza-2-deoxycytidine and vitamin D to suppress KSHV-associated cancer cell growth

  3. PDLIM2 expression is essential for feedback regulation of the beta1-integrin-RhoA (show RHOA Antibodies) signalling axis and integration of cellular microenvironment signals with gene expression to control the polarity of breast epithelial acini structures.

  4. PDLIM2 integrates cytoskeleton signaling with gene expression in epithelial differentiation by controlling the stability of key transcription factors and COP9 (show COPS8 Antibodies) signalosome activity.

  5. PDLIM2 was a direct target gene of 1,25(OH)2D3

  6. Pdlim2 is a novel actin-regulating protein of podocyte foot processes that may have a role in the pathogenesis of glomerular diseases.

  7. PDLIM2 binds to Tax (show CNTN2 Antibodies) directly, which was mediated by a putative alpa-helix motif of PDLIM2 at amino acids 236-254.

  8. PDLIM2, an essential terminator of NF-kappaB (show NFKB1 Antibodies) activation, is repressed in both estrogen receptor (show ESR1 Antibodies)-positive and estrogen receptor (show ESR1 Antibodies)-negative breast cancer cells, suggesting one important mechanism for the constitutive activation of NF-kappaB (show NFKB1 Antibodies).

  9. Data show that the PDLIM2 repression was independent of the viral regulatory protein Tax (show CNTN2 Antibodies) because neither short-term induction nor long-term stable expression of Tax (show CNTN2 Antibodies) could downregulate PDLIM2 expression.

  10. Knockdown of Mystique 2 with small interfering RNA abrogated both adhesion and migration in MCF10A and MCF-7 cells

PDLIM2 Antigen Profile

Protein Summary

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with PDLIM2

  • PDZ and LIM domain 2 (Pdlim2) antibody
  • PDZ and LIM domain 2 (mystique) (PDLIM2) antibody
  • 4732462F18Rik antibody
  • MYSTIQUE antibody
  • SLIM antibody

Protein level used designations for PDLIM2

PDZ and LIM domain protein 2 , PDZ-LIM protein mystique , STAT-interacting LIM protein , mystique , alpha-actinins and filamin-interacting protein

GENE ID SPECIES
213019 Mus musculus
290354 Rattus norvegicus
64236 Homo sapiens
512907 Bos taurus
486123 Canis lupus familiaris
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