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PGD Synthetase Proteins (PGDS)

The protein encoded by PGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). Additionally we are shipping PGD Synthetase Kits (14) and PGD Synthetase Antibodies (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse PGDS PGDS 19215 O09114
Rat PGDS PGDS 25526 P22057
PGDS 5730 P41222
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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PGDS Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for PGD Synthetase (PGDS) Interaction Partners

Mouse (Murine) PGD Synthetase (PGDS) interaction partners

  1. Ptgds (show PTGDS Proteins) is targeted and repressed by the CUL4B (show CUL4B Proteins)/PRC2 complex.

  2. Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.

  3. Prostaglandin D2 synthase is a novel MR target (show PTGDS Proteins) gene in adipocytes.

  4. When prostaglandin D2 synthase (show PTGDS Proteins) is upregulated it participates in the regulation of peripheral nervous system myelination.

  5. expression of L-PGDS (show PTGDS Proteins) in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.

  6. Silencing of PTGDS (show PTGDS Proteins) also alleviated H-rev107 (show HRASLS Proteins)-mediated suppression of cell migration and invasion

  7. In this report, we show for the first time that alteration of the P (show PTGDS Proteins)TGDS-governed PGD2 pathway disturbs testicular migration in mice.

  8. Data indicate a PLA2G3 (show PLA2G3 Proteins)-lipocalin (show APOD Proteins)-type PGD2 synthase (L-PGDS)-PGD2 (show PTGDS Proteins) receptor DP1 (show PTGDR Proteins) loop that drives mast cell maturation.

  9. The levels of lipocalin (show APOD Proteins)-type prostaglandin D2 synthase (show PTGDS Proteins), and its product PGD2 (show PTGDS Proteins) each varied significantly among background strains of mice after wounding, and the highest Ptgds (show PTGDS Proteins) and PGD2 (show PTGDS Proteins) levels were associated with the lowest amount of regeneration.

  10. L-PGDS (show PTGDS Proteins) and PPARgamma2 (show PPARG Proteins) coordinate to regulate carbohydrate and lipid metabolism.

Human PGD Synthetase (PGDS) interaction partners

  1. Hematopoietic prostaglandin D synthase (show HPGDS Proteins) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  2. levels of L-PGDS (show PTGDS Proteins) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  3. PTGDS (show PTGDS Proteins) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  4. Expression of MR and prostaglandin D2 synthase (show PTGDS Proteins) is strongly correlated in adipose tissues from obese patients.

  5. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (show PTGDS Proteins) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

  6. These results suggest that L-PGDS (show PTGDS Proteins) acted as a scavenger of biliverdin, which is a molecule not found in normal CSF (show CSF2 Proteins).

  7. Lipocalin (show APOD Proteins)-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor (show ADRA1A Proteins) DP1 (show PTGDR Proteins) in an agonist-independent manner.

  8. Among NSTE-ACS (show PLA2G15 Proteins) patients, BTP and CysC (show CST3 Proteins) were superior to conventional renal parameters for predicting MB, and improved clinical stratification for hemorrhagic risk.

  9. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase (show PTGDS Proteins).

  10. betaTP, beta2M, CysC (show CST3 Proteins), and creatinine differ in their associations with demographic and clinical factors, suggesting variation in their non-glomerular filtration rate determinants.

PGD Synthetase (PGDS) Protein Profile

Protein Summary

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with PGD Synthetase Proteins (PGDS)

  • prostaglandin D2 synthase (brain) (Ptgds)
  • prostaglandin D2 synthase 21kDa (brain) (PTGDS)
  • 21kDa protein
  • L-PGDS protein
  • LPGDS protein
  • PDS protein
  • PGD2 protein
  • PGDS protein
  • PGDS2 protein
  • PH2DISO protein
  • Ptgs3 protein

Protein level used designations for PGD Synthetase Proteins (PGDS)

PGD2 synthase , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin-D synthase , prostaglandin D2 synthase (21 kDa, brain) , prostaglandin-D2 synthase , prostaglandin-H2 D-isomerase , PGDS , PGDS2 , Prostaglandin D synthase , beta-trace protein , cerebrin-28 , lipocalin-type prostaglandin D synthase , prostaglandin D synthase

GENE ID SPECIES
19215 Mus musculus
25526 Rattus norvegicus
5730 Homo sapiens
403740 Canis lupus familiaris
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