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catalyzes conversion of prostaglandin H2 to prostaglandin D2, a major prostaglandin that mediates sleep, body temperature, hormone release, and odor responses. Additionally we are shipping PGD Synthetase Antibodies (12) and PGD Synthetase Proteins (1) and many more products for this protein.
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Exposure of macrophages to cyclooxygenase (COX-2 (show COX2 ELISA Kits)) inhibitors RhoA (show RHOA ELISA Kits) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (show PTGDS ELISA Kits) receptors or the hepatocyte growth factor (HGF (show HGF ELISA Kits)) receptor c-Met (PHA (show LBR ELISA Kits)-665752), reversed EMT (show ITK ELISA Kits) inhibition by the conditioned medium
Ptgds (show PTGDS ELISA Kits) is targeted and repressed by the CUL4B (show CUL4B ELISA Kits)/PRC2 complex.
Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.
Prostaglandin D2 synthase is a novel MR target (show PTGDS ELISA Kits) gene in adipocytes.
When prostaglandin D2 synthase (show PTGDS ELISA Kits) is upregulated it participates in the regulation of peripheral nervous system myelination.
expression of L-PGDS (show PTGDS ELISA Kits) in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.
Silencing of PTGDS also alleviated H-rev107-mediated suppression of cell migration and invasion
In this report, we show for the first time that alteration of the P (show PTGDS ELISA Kits)TGDS-governed PGD2 pathway disturbs testicular migration in mice.
Data indicate a PLA2G3 (show PLA2G3 ELISA Kits)-lipocalin (show APOD ELISA Kits)-type PGD2 synthase (L-PGDS)-PGD2 (show PTGDS ELISA Kits) receptor DP1 (show PTGDR ELISA Kits) loop that drives mast cell maturation.
The levels of lipocalin (show APOD ELISA Kits)-type prostaglandin D2 synthase (show PTGDS ELISA Kits), and its product PGD2 (show PTGDS ELISA Kits) each varied significantly among background strains of mice after wounding, and the highest Ptgds (show PTGDS ELISA Kits) and PGD2 (show PTGDS ELISA Kits) levels were associated with the lowest amount of regeneration.
Serum levels of beta trace protein and beta 2 microglobulin (show B2M ELISA Kits) can be used to predict residual kidney function in hemodialysis patients.
BTP and B2M (show B2M ELISA Kits) levels are less affected than serum by amputation, and should be considered for future study of GFR (show RAPGEF5 ELISA Kits) estimation
Hematopoietic prostaglandin D synthase (show HPGDS ELISA Kits) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function
levels of L-PGDS (show PTGDS ELISA Kits) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.
PTGDS (show PTGDS ELISA Kits) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.
Expression of MR and prostaglandin D2 synthase (show PTGDS ELISA Kits) is strongly correlated in adipose tissues from obese patients.
These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (show PTGDS ELISA Kits) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.
These results suggest that L-PGDS (show PTGDS ELISA Kits) acted as a scavenger of biliverdin, which is a molecule not found in normal CSF (show CSF2 ELISA Kits).
Lipocalin (show APOD ELISA Kits)-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor (show ADRA1A ELISA Kits) DP1 (show PTGDR ELISA Kits) in an agonist-independent manner.
Among NSTE-ACS (show PLA2G15 ELISA Kits) patients, BTP and CysC (show CST3 ELISA Kits) were superior to conventional renal parameters for predicting MB, and improved clinical stratification for hemorrhagic risk.
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
, glutathione-independent PGD synthase
, glutathione-independent PGD synthetase
, lipocalin-type prostaglandin-D synthase
, prostaglandin D2 synthase (21 kDa, brain)
, prostaglandin-D2 synthase
, prostaglandin-H2 D-isomerase
, Prostaglandin D synthase
, beta-trace protein
, lipocalin-type prostaglandin D synthase
, prostaglandin D synthase