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PHD Finger Protein 6 Proteins (PHF6)

PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. Additionally we are shipping PHF6 Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PHF6 84295 Q8IWS0
PHF6 70998 Q9D4J7
Rat PHF6 PHF6 100359714  
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Top PHF6 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,995.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

PHF6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for PHD Finger Protein 6 (PHF6) Interaction Partners

Human PHD Finger Protein 6 (PHF6) interaction partners

  1. Female phenotypes of Borjeson-Forssman-Lehmann syndrome patients with PHF6 mutations

  2. Our RBBP4 (show RBBP4 Proteins)-PHF6 complex structure provides insights into the molecular basis of PHF6-NuRD complex interaction and implicates a role for PHF6 in chromatin structure modulation and gene regulation.

  3. Phf6 is a "lineage-specific" cancer gene that plays opposing roles in developmentally distinct hematopoietic malignancies.

  4. The PHF6 tumor suppressor gene was targeted in acute lymphoblastic leukemia by microRNA-128-3p.

  5. Our report confirms that PHF6 loss in females results in a recognizable phenotype overlapping with Coffin-Siris syndrome and distinct from Borjeson-Forssman-Lehmann syndrome.

  6. Recurrent microdeletion was detected in Xq26.3, causing loss of PHF6 expression, a potential tumor suppressor gene, and the miR (show MLXIP Proteins)-424, which is involved in the development of acute myeloid leukemia (show BCL11A Proteins).

  7. The findings show that de novo mutations in PHF6 in females result in a recognisable phenotype which overlap with Borjeson-Forssman-Lehmann syndrome but also has additional distinct features, thus adding a new facet to this disorder.

  8. these data support the hypothesis that PHF6 may function as a transcriptional repressor using its ePHD domains binding to the promoter region of its repressed gene

  9. Data suggest that mutations of PHF6 are associated with chronic myeloid leukemia (CML) progression.

  10. These results reveal that the key function of PHF6 is involved in regulating rRNA synthesis, which may contribute to its roles in cell cycle control, genomic maintenance, and tumor suppression.

Mouse (Murine) PHD Finger Protein 6 (PHF6) interaction partners

  1. These results place miR (show MLXIP Proteins)-128 upstream of PHF6 in a pathway vital for cortical lamination as well as for the development of neuronal morphology and intrinsic excitability.

  2. As part of a cell-intrinsic transcriptional pathway, PHF6 regulates neuronal migration in the brain.

  3. Strongest Phf6 gene expression and nuclear localisation of Phf6 protein were observed in the developing central nervous system, the anterior pituitary gland, the primordia of facial structures and the limb buds.

PHF6 Protein Profile

Protein Summary

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Gene names and symbols associated with PHD Finger Protein 6 Proteins (PHF6)

  • PHD finger protein 6 (phf6)
  • PHD finger protein 6 (PHF6)
  • PHD finger protein 6 (LOC100225613)
  • PHD finger protein 6 (LOC100346149)
  • PHD finger protein 6 (Phf6)
  • 2700007B13Rik protein
  • 4931428F02Rik protein
  • BFLS protein
  • BORJ protein
  • CENP-31 protein
  • mKIAA1823 protein
  • wu:fa22g03 protein
  • zgc:55403 protein

Protein level used designations for PHD Finger Protein 6 Proteins (PHF6)

PHD finger protein 6 , PHD-like zinc finger protein , centromere protein 31

GENE ID SPECIES
327070 Danio rerio
495066 Xenopus laevis
707390 Macaca mulatta
779543 Xenopus (Silurana) tropicalis
100151997 Sus scrofa
100225613 Taeniopygia guttata
100346149 Oryctolagus cuniculus
100379647 Monodelphis domestica
735789 Pan troglodytes
100054177 Equus caballus
84295 Homo sapiens
422235 Gallus gallus
612921 Canis lupus familiaris
518186 Bos taurus
70998 Mus musculus
100359714 Rattus norvegicus
100174671 Pongo abelii
Selected quality suppliers for PHF6 Proteins (PHF6)
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