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anti-PHD Finger Protein 6 (PHF6) Antibodies

PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. Additionally we are shipping PHF6 Proteins (7) and PHF6 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHF6 84295 Q8IWS0
PHF6 70998 Q9D4J7
PHF6 100359714  
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Top anti-PHF6 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PHF6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHF6 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHF6 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: PHF6 Antibody [ABIN2611772] - Image from a customer review testing on 293T cells. 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PHF6 Antibody [NBP1-88646] - Staining of human colon shows strong nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PHF6 Antibody [NBP1-88646] - Staining of human cell line U-251MG shows positivity in nucleus & nucleoli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: PHF6 Antibody [NBP2-19799] - Sample (30 ug of whole cell lysate) A: MCF-7 10% SDS PAGE gel, diluted at 1:1000. Immunocytochemistry/Immunofluorescence: PHF6 Antibody [NBP2-19799] - Analysis of paraformaldehyde-fixed MCF-7, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

PHF6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-PHF6 Antibodies

  1. Human Polyclonal PHF6 Primary Antibody for WB - ABIN2784475 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

  2. Human Polyclonal PHF6 Primary Antibody for ICC, IF - ABIN261177 : Meacham, Lawton, Soto-Feliciano, Pritchard, Joughin, Ehrenberger, Fenouille, Zuber, Williams, Young, Hemann: A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. in Genes & development 2015 (PubMed)

  3. Human Polyclonal PHF6 Primary Antibody for ICC, IF - ABIN4345225 : Pontén, Jirström, Uhlen: The Human Protein Atlas--a tool for pathology. in The Journal of pathology 2008 (PubMed)

  4. Cow (Bovine) Polyclonal PHF6 Primary Antibody for WB - ABIN2784476 : Vallée, Chevrier, Graham, Lazzaro, Lavigne, Hunter, Picketts: A novel PHF6 mutation results in enhanced exon skipping and mild Börjeson-Forssman-Lehmann syndrome. in Journal of medical genetics 2004 (PubMed)

More Antibodies against PHF6 Interaction Partners

Human PHD Finger Protein 6 (PHF6) interaction partners

  1. PHF6 localizes to the sub-nucleolar fibrillar center where it binds to rDNA-coding sequences. PHF6 mediates the overall levels of ribosome biogenesis within a cell.

  2. Our results suggest that PHF6 may function as an oncogenic factor in several types of cancer. We also hypothesize that PHF6 may also play its role in a tissue-specific manner. Our findings suggest further investigations regarding the exact role of PHF6 in tumor types.

  3. Female phenotypes of Borjeson-Forssman-Lehmann syndrome patients with PHF6 mutations

  4. Our RBBP4 (show RBBP4 Antibodies)-PHF6 complex structure provides insights into the molecular basis of PHF6-NuRD complex interaction and implicates a role for PHF6 in chromatin structure modulation and gene regulation.

  5. Phf6 is a "lineage-specific" cancer gene that plays opposing roles in developmentally distinct hematopoietic malignancies.

  6. The PHF6 tumor suppressor gene was targeted in acute lymphoblastic leukemia by microRNA-128-3p.

  7. Our report confirms that PHF6 loss in females results in a recognizable phenotype overlapping with Coffin-Siris syndrome and distinct from Borjeson-Forssman-Lehmann syndrome.

  8. Recurrent microdeletion was detected in Xq26.3, causing loss of PHF6 expression, a potential tumor suppressor gene, and the miR (show MLXIP Antibodies)-424, which is involved in the development of acute myeloid leukemia (show BCL11A Antibodies).

  9. The findings show that de novo mutations in PHF6 in females result in a recognisable phenotype which overlap with Borjeson-Forssman-Lehmann syndrome but also has additional distinct features, thus adding a new facet to this disorder.

  10. these data support the hypothesis that PHF6 may function as a transcriptional repressor using its ePHD domains binding to the promoter region of its repressed gene

Mouse (Murine) PHD Finger Protein 6 (PHF6) interaction partners

  1. These results place miR (show MLXIP Antibodies)-128 upstream of PHF6 in a pathway vital for cortical lamination as well as for the development of neuronal morphology and intrinsic excitability.

  2. As part of a cell-intrinsic transcriptional pathway, PHF6 regulates neuronal migration in the brain.

  3. Strongest Phf6 gene expression and nuclear localisation of Phf6 protein were observed in the developing central nervous system, the anterior pituitary gland, the primordia of facial structures and the limb buds.

PHF6 Antigen Profile

Protein Summary

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Gene names and symbols associated with PHF6

  • PHD finger protein 6 (phf6) antibody
  • PHD finger protein 6 (PHF6) antibody
  • PHD finger protein 6 (LOC100225613) antibody
  • PHD finger protein 6 (LOC100346149) antibody
  • PHD finger protein 6 (Phf6) antibody
  • 2700007B13Rik antibody
  • 4931428F02Rik antibody
  • BFLS antibody
  • BORJ antibody
  • CENP-31 antibody
  • mKIAA1823 antibody
  • wu:fa22g03 antibody
  • zgc:55403 antibody

Protein level used designations for PHF6

PHD finger protein 6 , PHD-like zinc finger protein , centromere protein 31

GENE ID SPECIES
327070 Danio rerio
495066 Xenopus laevis
707390 Macaca mulatta
779543 Xenopus (Silurana) tropicalis
100151997 Sus scrofa
100225613 Taeniopygia guttata
100346149 Oryctolagus cuniculus
100379647 Monodelphis domestica
735789 Pan troglodytes
100054177 Equus caballus
84295 Homo sapiens
422235 Gallus gallus
612921 Canis lupus familiaris
518186 Bos taurus
70998 Mus musculus
100359714 Rattus norvegicus
100174671 Pongo abelii
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