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anti-PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) (PIF1) Antibodies

PIF1 is a 5-prime-to-3-prime DNA helicase that negatively regulates telomerase (see TERT\\\\; MIM 187270), a reverse transcriptase that maintains telomere length (Zhang et al., 2006 [PubMed 16522649]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIF1 80119 Q9H611
PIF1 367645 Q1HG60
PIF1 208084 Q80SX8
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Top anti-PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of PIF1 expression in HeLa (A), HEK293T (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$581.17
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 2 to 3 Days
$187.00
Details
Human Rabbit Un-conjugated   100 μL Log in to see 9 to 19 Days
$354.05
Details

PIF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Rat (Rattus)


Mouse (Murine)


More Antibodies against PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) Interaction Partners

Human PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) (PIF1) interaction partners

  1. Authors characterised a functional role for human PIF1 in DNA replication that becomes important for cell growth under oncogenic stress.

  2. Pif1 readily unfolds a parallel quadruplex DNA substrate in a multiturnover reaction and also generates some product under single cycle conditions

  3. A minimum of 10 oligonucleotide bases are required for PIF1 binding and the hydrolysis of ATP.

  4. the yeast ortholog of Pif1 appears to move along DNA in single nucleotide or base pair steps, powered by hydrolysis of 1 molecule of ATP.

  5. Evidence that the PIF1 N-terminal (PINT) domain as crucial functions in PIF1 helicase.

  6. when expressed in yeast, human PIF1 suppressed both G-quadruplex-associated DNA damage and telomere lengthening

  7. PIF1 variant L319P was identified in three breast cancer families

  8. Findings suggest roles for PIF1 in S-phase entry and progression that are essential to protect human tumor cells from apoptosis.

  9. Human Pif1 could have a role in processing G4 structures that arise in the single-stranded nucleic acid intermediates formed during DNA replication and gene expression.

  10. Human PIF, like S. cerevisiae Pif1p, plays a role in telomerase regulation.

Mouse (Murine) PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) (PIF1) interaction partners

  1. murine cells have evolved mechanisms to ensure the functional redundancy of Pif1 or Nbs1 (show NBN Antibodies) in the regulation of chromosome healing.

  2. Murine telomere homeostasis or genetic stability does not depend on mPif1 (show CCL23 Antibodies).

PIF1 5'-To-3' DNA Helicase Homolog (S. Cerevisiae) (PIF1) Antigen Profile

Protein Summary

PIF1 is a 5-prime-to-3-prime DNA helicase that negatively regulates telomerase (see TERT\; MIM 187270), a reverse transcriptase that maintains telomere length (Zhang et al., 2006

Gene names and symbols associated with PIF1

  • PIF1 5'-to-3' DNA helicase (PIF1) antibody
  • PIF1 5'-to-3' DNA helicase (Pif1) antibody
  • PIF1 5'-to-3' DNA helicase (pif1) antibody
  • PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) (Pif1) antibody
  • PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) (pif1) antibody
  • 4631410M14 antibody
  • AI449441 antibody
  • C15orf20 antibody
  • cb934 antibody
  • fe11d03 antibody
  • PIF antibody
  • wu:fe11d03 antibody
  • zgc:56161 antibody

Protein level used designations for PIF1

ATP-dependent DNA helicase PIF1 , DNA helicase PIF1 , DNA helicase homolog PIF1 , PIF1 5'-to-3' DNA helicase homolog , PIF1 DNA helicase , PIF1/RRM3 DNA helicase-like protein , petite integration frequency 1 , Pif1/Rrm3 DNA-helicase-like protein , DNA helicase-like protein , PIF1 homolog , Pif1/Rrm3 DNA helicase-like protein

GENE ID SPECIES
80119 Homo sapiens
367645 Rattus norvegicus
734585 Xenopus laevis
208084 Mus musculus
326729 Danio rerio
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