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Microtubule-binding protein essential for faithful chromosome segregation. Additionally we are shipping PINX1 Proteins (15) and PINX1 Kits (3) and many more products for this protein.
Showing 10 out of 65 products:
Human Polyclonal PINX1 Primary Antibody for ELISA, WB - ABIN565796
Ma, Wu, Liu, Xu, Li, Li: The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population. in Journal of cancer research and clinical oncology 2009
Show all 4 references for ABIN565796
Human Polyclonal PINX1 Primary Antibody for IHC, ELISA - ABIN1450857
Liao, Zhao, Song, Uchida, Yokoyama, Li: Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2000
Show all 2 references for ABIN1450857
Human Polyclonal PINX1 Primary Antibody for ELISA, WB - ABIN184695
Zhou, Lu: The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. in Cell 2001
Human Polyclonal PINX1 Primary Antibody for EIA, WB - ABIN487973
Banik, Counter: Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. in The Journal of biological chemistry 2004
The stability of PinX1 is maintained in nucleolus in the presence of TERT (show TERT Antibodies).
PinX1 negatively regulated ccRCC metastasis and the expression of MMP-2 (show MMP2 Antibodies) and NF-kappaB (show NFKB1 Antibodies)-p65 (show GORASP1 Antibodies)
High PinX1 expression significantly correlated with a worse 5-year overall and disease-specific survival in gliomas.
Data show a novel molecular mechanism for PINX1 as an attenuator of estrogen receptor (show ESR1 Antibodies) activity in breast cancer cell lines, furthering its role as a tumor suppressor gene in breast cancer.
PinX1 protein expression is decreased in colorectal cancer patients and predicts a poor prognosis.
PinX1 inhibits cell proliferation, migration and invasion in glioma cells.
PinX1 expression was an independent negative prognostic factor for breast cancer patients.
Two novel markers, rs7840785 (PINX1) and rs7844465 (ZHX2 (show ZHX2 Antibodies)), are significantly associated with carotid intima-media thickness.
These results confirmed the role of PinX1 as a major tumor suppressor gene in breast cancer cell lines.
Data confirmed that levels of PinX1 and caspase 3 (show CASP3 Antibodies), 8 and 9 expression were closely linked to the poor prognosis of colorectal cancer.
PinX1 heterozygosity and PinX1 knockdown in mouse embryonic fibroblasts activated telomerase and led to concomitant telomerase-dependent chromosomal instability.
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).
PIN2-interacting protein 1
, 67-11-3 protein
, PIN2 interacting protein 1
, PIN2/TERF1-interacting telomerase inhibitor 1
, TRF1-interacting protein 1
, hepatocellular carcinoma-related putative tumor suppressor
, liver-related putative tumor suppressor
, pin2-interacting protein X1
, protein 67-11-3
, PIN2-interacting protein X1
, PIN2/TRF1-interacting protein
, Pin2-interacting protein X1