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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 Proteins (PINX1)

Microtubule-binding protein essential for faithful chromosome segregation. Additionally we are shipping PINX1 Antibodies (69) and PINX1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PINX1 54984 Q96BK5
PINX1 72400 Q9CZX5
PINX1 305963 A4L691
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Top PINX1 Proteins at antibodies-online.com

Showing 9 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,893.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

PINX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced PINX1 Proteins

  1. Human PINX1 Protein expressed in Escherichia coli (E. coli) - ABIN666767 : Yoo, Oh, Park: Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres. in Journal of molecular biology 2009 (PubMed)
    Show all 2 references for ABIN666767

More Proteins for PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) Interaction Partners

Human PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) interaction partners

  1. The stability of PinX1 is maintained in nucleolus in the presence of TERT (show TERT Proteins).

  2. PinX1 negatively regulated ccRCC metastasis and the expression of MMP-2 (show MMP2 Proteins) and NF-kappaB (show NFKB1 Proteins)-p65 (show GORASP1 Proteins)

  3. High PinX1 expression significantly correlated with a worse 5-year overall and disease-specific survival in gliomas.

  4. Data show a novel molecular mechanism for PINX1 as an attenuator of estrogen receptor (show ESR1 Proteins) activity in breast cancer cell lines, furthering its role as a tumor suppressor gene in breast cancer.

  5. PinX1 protein expression is decreased in colorectal cancer patients and predicts a poor prognosis.

  6. PinX1 inhibits cell proliferation, migration and invasion in glioma cells.

  7. PinX1 expression was an independent negative prognostic factor for breast cancer patients.

  8. Two novel markers, rs7840785 (PINX1) and rs7844465 (ZHX2 (show ZHX2 Proteins)), are significantly associated with carotid intima-media thickness.

  9. These results confirmed the role of PinX1 as a major tumor suppressor gene in breast cancer cell lines.

  10. Data confirmed that levels of PinX1 and caspase 3 (show CASP3 Proteins), 8 and 9 expression were closely linked to the poor prognosis of colorectal cancer.

Mouse (Murine) PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) interaction partners

  1. PinX1 heterozygosity and PinX1 knockdown in mouse embryonic fibroblasts activated telomerase and led to concomitant telomerase-dependent chromosomal instability.

PINX1 Protein Profile

Protein Summary

Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).

Gene names and symbols associated with PINX1

  • PIN2-interacting protein 1 (PINX1)
  • PIN2-interacting protein 1 (LOC100154593)
  • PIN2-interacting protein 1 (LOC100224341)
  • PIN2/TERF1 interacting, telomerase inhibitor 1 (PINX1)
  • PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1)
  • 67-11-3 protein
  • 2210403I16Rik protein
  • 2610028A01Rik protein
  • AU024023 protein
  • LPTL protein
  • LPTS protein
  • LPTS1 protein
  • PINX1 protein
  • RGD1566025 protein

Protein level used designations for PINX1

PIN2-interacting protein 1 , 67-11-3 protein , PIN2 interacting protein 1 , PIN2/TERF1-interacting telomerase inhibitor 1 , TRF1-interacting protein 1 , hepatocellular carcinoma-related putative tumor suppressor , liver-related putative tumor suppressor , pin2-interacting protein X1 , protein 67-11-3 , PIN2-interacting protein X1 , PIN2/TRF1-interacting protein , Pin2-interacting protein X1

GENE ID SPECIES
701523 Macaca mulatta
100154593 Sus scrofa
100224341 Taeniopygia guttata
54984 Homo sapiens
607910 Canis lupus familiaris
525027 Bos taurus
72400 Mus musculus
305963 Rattus norvegicus
Selected quality suppliers for PINX1 Proteins (PINX1)
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