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Required for ciliogenesis (By similarity).. Additionally we are shipping POC1B Proteins (5) and many more products for this protein.
Showing 10 out of 31 products:
Human Polyclonal POC1B Primary Antibody for EIA, IHC (p) - ABIN955560
Pearson, Osborn, Giddings, Beales, Winey: Basal body stability and ciliogenesis requires the conserved component Poc1. in The Journal of cell biology 2009
Show all 5 references for ABIN955560
Cow (Bovine) Polyclonal POC1B Primary Antibody for WB - ABIN2786288
Higa, Wu, Ye, Kobayashi, Sun, Zhang: CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. in Nature cell biology 2006
Human Polyclonal POC1B Primary Antibody for IHC (p), WB - ABIN654969
Keller, Geimer, Romijn, Yates, Zamora, Marshall: Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. in Molecular biology of the cell 2009
Study indicates that POC1B is required for retinal integrity, and is proposed POC1B mutations as a probable cause for Joubert syndrome with severe polycystic kidney disease.
POC1B is a novel gene for a new disease typical of cone-rod dystrophy except that patients did not report night blindness.
POC1B mutations result in a defect of the photoreceptor sensory cilium and thus affect cone and rod photoreceptors.
Poc1A (show POC1A Antibodies) and Poc1B play redundant, but essential, roles in generation of stable centrioles, but Poc1B may have additional independent functions during cell cycle progression.
Poc1B is required for primary ciliogenesis; Poc1 provides a molecular link between the assembly and stability of centrioles for ciliary-based motility in T. thermophila and cilia formation and function in zebrafish and humans
Based on these data, we propose that Pix1 and Pix2 (show POC1A Antibodies) are microtubule-associated adaptor proteins that likely contribute to a range of developmental and cell division processes.
data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia
Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans
Required for ciliogenesis (By similarity).
POC1 centriolar protein homolog B
, WD repeat-containing protein 51B
, WD repeat domain 51B