You are viewing an incomplete version of our website. Please click to reload the website as full version.

POU Class 1 Homeobox 1 Proteins (POU1F1)

POU1F1 encodes a member of the POU family of transcription factors that regulate mammalian development. Additionally we are shipping POU Class 1 Homeobox 1 Antibodies (11) and POU Class 1 Homeobox 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
POU1F1 5449 P28069
POU1F1 25517  
POU1F1 18736 Q00286
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top POU Class 1 Homeobox 1 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,768.33
Details
Yeast Oncorhynchus mykiss His tag   1 mg Log in to see 56 to 66 Days
$2,977.33
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,992.00
Details

POU1F1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for POU Class 1 Homeobox 1 (POU1F1) Interaction Partners

Human POU Class 1 Homeobox 1 (POU1F1) interaction partners

  1. investigated the specific mutations in PROP1 (show PROP1 Proteins), POU1F1, LHX3 (show LHX3 Proteins), and HESX1 (show HESX1 Proteins) genes in patients with combined pituitary hormone (show CGA Proteins) deficiency (CPHD) in Turkey

  2. Pit-1 regulates MMP-1 (show MMP1 Proteins) and MMP-13 (show MMP13 Proteins), and that inhibition of MMP-13 (show MMP13 Proteins) blocked invasiveness to lung in Pit-1-overexpressed breast cancer cells.

  3. These results suggest that the anti-PIT-1 antibody is not a cause but a marker of anti-PIT-1 antibody syndrome, in which cytotoxic T lymphocytes play a pivotal role in the pathogenesis.

  4. New target genes of POU1F1 and downstream networks controlled by this factor.

  5. Expression analysis of HMGA1 (show HMGA1 Proteins), HMGA2 and PIT1 in human pituitary adenomas of different histological types revealed a direct correlation between PIT1 and HMGA (show HGD Proteins) expression levels.

  6. This is the first report of a mutation at the exon 2 donor splice site of POU1F1, affecting TAD (show CRTAM Proteins)-R2.

  7. HSII confers robust POU1F1-dependent activation of hGH-N (show GH1 Proteins) in this system.

  8. study, which identifies a novel loss-of-function mutation in POU1F1, describes the phenotype of a rare condition in a patient followed from the first weeks of life to adulthood

  9. Data show no mutations in HESX1 (show HESX1 Proteins), PROP1 (show PROP1 Proteins), and POU1F1 genes, seven different mutations in CTNNB1 (show CTNNB1 Proteins) in 8/16 patients, and hyperexpression of miR (show MLXIP Proteins)-150.

  10. Pit-1 overexpression or knockdown in human breast cancer cell lines induced profound phenotypic changes in the expression of proteins involved in cell proliferation, apoptosis, and invasion.

Pig (Porcine) POU Class 1 Homeobox 1 (POU1F1) interaction partners

  1. The association between a MspI polymorphism in the porcine PIT-1 gene and backfat thickness in Belgian slaughter pigs was confirmed in a number of breeds. In crossbred progeny the MspI D allele could possibly be associated with a higher backfat thickness.

  2. paper demonstrated that the genetic variation in intron 1 of the POU1F1 (Pit1) gene was high and these polymorphisms may provide useful makers for QTL analysis

  3. The polymorphisms in the PIT1 gene of 103 pigs were examined and their frequencies in the maternal and paternal lineages of the Pietrain and Large White breeds, were compared.

Cow (Bovine) POU Class 1 Homeobox 1 (POU1F1) interaction partners

  1. The association of IGF1 (show IGF1 Proteins), GH, and PIT1 markers with growth and reproductive traits were assessed.

  2. homozygote genotypes of GH (LL) and beta-LG (AA) were superior compared to heterozygote genotypes, whereas, the heterozygote genotype of Pit-1 gene (AB) was desirable

  3. results showed that GC genotype at 1178 locus of POU1F1 gene was advantageous for milk yield, milk protein (show CSN2 Proteins) yield, and milk fat yield

  4. Study of genetic variation in Yakutian cattle (Bos taurus L.) using the prolactin bPRL, growth hormone bGH, and transcription factor bPit-1 genes

  5. No significant associations of the TaqI polymorphism of the bovine POU1F1 gene with body weight and average daily gain for different growth periods were observed.

  6. The POU1F1 gene is associated with economically important traits in dairy cattle; an SNP in exon 3 of POU1F1 that changes a proline to a histidine was identified.

  7. Results estimate the allele frequencies in polymorphic site of exon six of POU1F1 in three Iranian native and Holstein cattle, and show no significant association between POU1F1 polymorphism and milk production.

  8. The association of the polymorphism of the POU1F1 gene with growth traits among Qinchuan, Limousin x Qinchuan, Angus x Qinchuan and Germany Yellow x Qinchuan crosses was analyzed.

Mouse (Murine) POU Class 1 Homeobox 1 (POU1F1) interaction partners

  1. The maintenance conformation at the Pit-1 chromatin locus is dependent on autoregulation by Pit-1 protein.

  2. Mice with hypomorphic expression of the sodium-phosphate cotransporter PiT1/Slc20a1 (show SLC20A1 Proteins) have an unexpected normal bone mineralization.

  3. EKLF (show KLF1 Proteins) increases PIT1 expression during RBC (show CACNA1C Proteins) maturation by binding to its promoter in vivo.

  4. Results suggested that Pit-1 w could be involved in the paracrine/autocrine system in mice and may be necessary for normal testicular function via its possible role in regulating PRL (show PRL Proteins) expression in testicular germ cells.

  5. Significant differences in gene expression were noted between each mutant and their normal littermates, as well as between Prop1 (show PROP1 Proteins) and Pit1 mutants.

  6. Data indicate that protective alleles of Mtap1a (show MAP1A Proteins) are not sufficient to rescue DW/J-Pou1f1dw/dw mutant hearing.

  7. Mouse Pit-1 w plays a role in spermatogenesis. This is the first report demonstrating the expression of Pit-1 variants arising from alternative promoters in mammals.

  8. miR (show MLXIP Proteins)-26b regulates Pit-1 expression by inhibiting Lef-1 (show LEF1 Proteins) expression and may promote Pit-1 lineage differentiation during pituitary development.

  9. Data show that the PiT-1 embryos displayed anemia, a defect in yolk sac (show ADCY10 Proteins) vasculature, and arrested growth, and indicate that PiT-1 has a necessary, nonredundant role in embryonic development.

  10. Pit1 mutation may result in physiological homeostasis that favors longevity

POU Class 1 Homeobox 1 (POU1F1) Protein Profile

Protein Summary

This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with POU1F1

  • POU class 1 homeobox 1 (POU1F1)
  • POU class 1 homeobox 1 (Pou1f1)
  • POU domain, class 1, transcription factor 1 (Pou1f1)
  • POU domain, class 1, transcription factor 1 (pou1f1)
  • CPHD1 protein
  • dw protein
  • dwarf protein
  • GHF-1 protein
  • GHF1 protein
  • GHF1A protein
  • Hmp1 protein
  • PIT-1 protein
  • Pit-1* protein
  • pit1 protein
  • Pit1-rs1 protein
  • PIT1Z protein
  • POU1F1a protein

Protein level used designations for POU1F1

POU domain, class 1, transcription factor 1 , growth hormone factor 1 , pituitary-specific positive transcription factor 1 , pituitary-specific transcription factor 1 , POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) , Pit-1/GHF-1 , pituitary specific transcription factor , pituitary-specific positive transcription factor 1 variant alpha , GHF-1 , pituitary specific transcription factor 1 , POU-domain transcriptional regulator , pituitary growth factor , Pituary specific transcription factor 1 (growth hormone factor 1) , homeodomain protein for Growth Hormone (GH) , pit-1 , pituitary-specific positive transcription factor 1 variant w , PIT-1 , pit-1/GHF-1 transcription factor , pituitary specific transcription factor 1, related sequence 1 , Pit-1

GENE ID SPECIES
5449 Homo sapiens
374215 Gallus gallus
403753 Canis lupus familiaris
397325 Sus scrofa
282315 Bos taurus
25517 Rattus norvegicus
443370 Ovis aries
719349 Macaca mulatta
18736 Mus musculus
100136675 Oncorhynchus mykiss
Selected quality suppliers for POU Class 1 Homeobox 1 Proteins (POU1F1)
Did you look for something else?