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POU6F2 encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. Additionally we are shipping POU Class 6 Homeobox 2 Proteins (5) and many more products for this protein.
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Human Polyclonal POU6F2 Primary Antibody for EIA, WB - ABIN954262
Anney, Klei, Pinto, Regan, Conroy, Magalhaes, Correia, Abrahams, Sykes, Pagnamenta, Almeida, Bacchelli, Bailey, Baird, Battaglia, Berney, Bolshakova, Bölte, Bolton, Bourgeron, Brennan, Brian, Carson, Casallo, Casey, Chu, Cochrane, Corsello, Crawford, Cros: A genome-wide scan for common alleles affecting risk for autism. in Human molecular genetics 2010
Show all 4 references for ABIN954262
Chicken Polyclonal POU6F2 Primary Antibody for WB - ABIN2780840
Perotti, De Vecchi, Testi, Lualdi, Modena, Mondini, Ravagnani, Collini, Di Renzo, Spreafico, Terenziani, Sozzi, Fossati-Bellani, Radice: Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14. in Human mutation 2004
observations suggest that POU6F2 is a tumor suppressor and is involved in hereditary predisposition to Wilms tumor
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
POU class 6 homeobox 2
, POU domain, class 6, transcription factor 2
, Wilms tumor suppressor locus
, retina-derived POU domain factor 1
, retina-derived POU-domain factor-1