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POU Domain, Class 2, Transcription Factor 1 Proteins (POU2F1)

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Additionally we are shipping POU2F1 Antibodies (133) and POU2F1 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
POU2F1 5451 P14859
POU2F1 171068 P31503
POU2F1 18986 P25425
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Top POU2F1 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
Yeast Macropus eugenii His tag   1 mg Log in to see 56 to 66 Days
$2,097.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,828.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

POU2F1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)
,

Top referenced POU2F1 Proteins

  1. Human POU2F1 Protein expressed in Wheat germ - ABIN1315780 : Holt, Zhang, Binia, Dixon, Vandiedonck, Cookson, Knight, Moffatt: Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). in The Journal of allergy and clinical immunology 2011 (PubMed)

More Proteins for POU Domain, Class 2, Transcription Factor 1 (POU2F1) Interaction Partners

Human POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. Comparative analysis of various tumor lines showed no clear correlation between the expression level of Mts1/S100A4 (show S100A4 Proteins) and the content of Oct-1. However, at stable transfection of tumor cells with Oct (show Plxna2 Proteins)-1A, Oct (show Plxna2 Proteins)-1L, and Oct (show Plxna2 Proteins)-1X isoforms we detected an elevated level of Oct-1, which stimulated Mts1/S100A4 (show S100A4 Proteins) secretion.

  2. The response in Burkitt's lymphoma cells (Namalwa line) to camptothecin and dexamethasone of the Oct-1 target genes involved in the development of apoptosis depended, firstly, on the type of drug, secondly, on the concentration of Oct-1 in cells and, thirdly, on the Oct-1 isoform with which these cells were transfected

  3. Role of transcription factor Oct-1 in the regulation of expression of genes of the JAK (show JAK3 Proteins)-STAT (show STAT1 Proteins) signaling pathway in the Namalwa Burkitt's lymphoma cell line: overexpression of Oct-1 isoforms (Oct (show Plxna2 Proteins)-1A, Oct (show Plxna2 Proteins)-1L, and Oct (show Plxna2 Proteins)-1X) causes a decrease in the activity of four genes involved in the JAK (show JAK3 Proteins)-STAT (show STAT1 Proteins) signaling pathway-IFNAR2 (show IFNAR2 Proteins), STAT1 (show STAT1 Proteins), STAT2 (show STAT2 Proteins), and STAT4 (show STAT4 Proteins); STAT2 (show STAT2 Proteins) and STAT4 (show STAT4 Proteins) are direct targets for Oct-1 protein

  4. single-nucleotide polymorphisms of OCT1 have selective effects on the glycemic response to metformin

  5. OCT-1 plays a critical role in CD4 (show CD4 Proteins) T cells through regulating gene expression during differentiation and mediating long-range chromosomal interactions. (Review)

  6. Oct-1 is a direct link of transcription factors with the core transcriptional machinery and chromatin remodeling and, depending on other factors present in particular cell types, it can direct cell type specific regulation. (Review)

  7. OCT1 siRNA significantly reduced the proliferation rate of SW620 and LoVo cells, inhibited the migration and invasion, and could reverse EMT (show ITK Proteins) in these two CRC (show CALR Proteins) cells, indicating that OCT1 plays a critical role in Colorectal cancer progression

  8. levels of microRNA-451 (miR (show MLXIP Proteins)-451) are negatively regulated through the phosphorylation and inactivation of its direct transcriptional activator OCT1 by 5' AMP-activated protein kinase (show PRKAA2 Proteins)

  9. These results suggest that reduced OCT1 transport is an important determinant of metformin intolerance.

  10. POU2F1 activity regulates HOXD10 (show HOXD10 Proteins) and HOXD11 (show HOXD11 Proteins) gene expression in head and neck squamous cell carcinoma, promoting a proliferative and invasive phenotype.

Xenopus laevis POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. identified Oct-1 (POU2f1), a POU transcription factor (show POU2F3 Proteins), as a downstream target of Notch (show NOTCH1 Proteins) signaling by microarray based screen

Mouse (Murine) POU Domain, Class 2, Transcription Factor 1 (POU2F1) interaction partners

  1. These results suggest that Oct-1 and GATA-3 (show GATA3 Proteins)/Oct-2 direct Th2 cytokine gene expression in a cooperative manner.

  2. Findings indicate octamer transcription factor-1 (show HNF1A Proteins) (Oct1) and Oct binding factor 1 (show POU2AF1 Proteins) protein (OCA-B (show POU2AF1 Proteins)) as central mediators of CD4 (show CD4 Proteins)(+) T cell memory.

  3. levels of microRNA-451 (miR (show MLXIP Proteins)-451) are negatively regulated through the phosphorylation and inactivation of its direct transcriptional activator OCT1 by 5' AMP-activated protein kinase (show PRKAA2 Proteins)

  4. Oct1 mRNA expression was decreased in mice with both ob/ob and methionine/choline deficiency models of nonalcoholic steatohepatitis.

  5. OCT1 is a driver of synbindin (show TRAPPC4 Proteins)-mediated ERK (show EPHB2 Proteins) signalling and a promising marker for the prognosis and molecular subtyping of gastric cancer.

  6. studies implicate OCT1 as well as metformin in thiamine disposition, suggesting an intriguing and parallel mechanism for metformin and its major hepatic transporter in metabolic function.

  7. Th17 lineage differentiation is restrained by the Th2 locus via interchromosomal associations organized by Oct-1 and CTCF (show CTCF Proteins).

  8. inhibition of the DNA binding activity of transcriptional repressor OCT-1 is a mechanism by which ethanol up-regulates Slc711 expression.

  9. mammary cells express beta-casein (show CSN2 Proteins) in response to prolactin (show PRL Proteins) in a pathway that involves gap junction intracellular communication and OCT-1 and is independent of STAT5 (show STAT5A Proteins) nuclear translocation

  10. Oct1 plays an important role not only in the pharmacokinetics of cis (show CISH Proteins)-diammine(pyridine)chloroplatinum(II)(CDPCP), but also in its toxicities.

POU2F1 Protein Profile

Protein Summary

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993

Gene names and symbols associated with POU2F1

  • POU class 2 homeobox 1 (POU2F1)
  • POU class 2 homeobox 1 (Pou2f1)
  • POU class 2 homeobox 1 (pou2f1)
  • POU domain, class 2, transcription factor 1 (Pou2f1)
  • 2810482H01Rik protein
  • chOCT-1 protein
  • NF-A1 protein
  • oct-1 protein
  • oct-1B protein
  • Oct1 protein
  • Otf-1 protein
  • Otf1 protein
  • POU2F1 protein
  • pou2f1r protein

Protein level used designations for POU2F1

POU class 2 homeobox 1 , POU domain, class 2, transcription factor 1 , NF-A1 , OTF-1 , Octamer-binding transcription factor-1 , oct-1 , octamer-binding protein 1 , octamer-binding transcription factor 1 , octamer-binding protein (Oct-1) , octamer binding protein 1 , XOct1 , maternal transcription factor , xloct1-32 , ubiquitous transcription factor

GENE ID SPECIES
457486 Pan troglodytes
490360 Canis lupus familiaris
5451 Homo sapiens
171068 Rattus norvegicus
396463 Gallus gallus
397501 Sus scrofa
399316 Xenopus laevis
18986 Mus musculus
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