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POU Domain, Class 4, Transcription Factor 2 (POU4F2) ELISA Kits

member of the POU family of transcription factors\\\\; play key roles in the development of specific neuronal cell types [RGD, Feb 2006].. Additionally we are shipping POU4F2 Antibodies (35) and POU4F2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat POU4F2 POU4F2 171355  
Anti-Human POU4F2 POU4F2 5458 Q12837
Anti-Mouse POU4F2 POU4F2 18997 Q63934
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More ELISA Kits for POU4F2 Interaction Partners

Zebrafish POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. The cloning and expression profile of brn-3b in the zebrafish (Danio rerio) were assessed as the first step for understanding its role in the development of sensory systems.

Human POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. The genes BCL6 (show BCL6 ELISA Kits), NFE2 (show NFE2 ELISA Kits), POU4F2 and ELF4 are primary 1,25(OH)2D3 targets in THP-1 (show GLI2 ELISA Kits) cells

  2. Methylation levels of EOMES, HOXA9, POU4F2, TWIST1, VIM, and ZNF154 in urine specimens are promising diagnostic biomarkers for bladder cancer recurrence surveillance

  3. Levels of CDK4 (show CDK4 ELISA Kits) mRNA and protein correlate with levels of Brn-3b in breast cancer cell lines manipulated to express different levels of Brn-3b and in human breast cancer biopsies; Brn-3b can activate the CDK4 (show CDK4 ELISA Kits) promoter

  4. Brn-3b transcription factor contributes to proliferation of neuroblastoma (show ARHGEF16 ELISA Kits) cells in vivo and in vitro but may also influence progression and/or invasion during tumorigenesis.

  5. Brn-3b can, directly and indirectly (via interaction with the ER), activate HSP-27 (show HSPB1 ELISA Kits) expression, and this may represent one mechanism by which Brn-3b mediates its effects in breast cancer cells.

  6. Brn-3b expression has been shown to be a prerequisite for developmental survival of most retinal ganglion cells.

  7. first time that a Brn-3b POU family transcription factor has been shown to regulate a member of the catenin family, which provides insight into the molecular mechanisms by which Brn-3b expression may favour breast cancer progression and tumor invasion

  8. Two different microRNAs that potentially regulate the stability of Brn-3b have been identified in neuroblastoma (show ARHGEF16 ELISA Kits) cells.

  9. May act to alter growth properties of breast cancer and neuroblastoma (show ARHGEF16 ELISA Kits) cells by enhancing cyclin D1 (show CCND1 ELISA Kits) expression in these tumor cells.

  10. Brn3b specifies the RGC fate from multipotential precursors not only by promoting RGC differentiation but also by suppressing non-RGC differentiation programs as a safeguard mechanism.

Mouse (Murine) POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. Dynamic expression of Brn3b was identified in the somatosensory component of cranial nerves during different stages of development.

  2. Pou4f2 KO mice exhibit profound hyperglycemia, increased GSK3B expression, and decreased GLUT4 (show SLC2A4 ELISA Kits) expression. In C2C12 myocytes, Pou4f2 mRNA and protein are induced by glucose and inhibited by insulin (show INS ELISA Kits).

  3. Results suggest the existence of a coordinated mechanism by miR (show MLXIP ELISA Kits)-23a and miR (show MLXIP ELISA Kits)-374 to down regulate Brn3b and ultimately regulate the development of retinal ganglion cells from their precursors

  4. Pou4f2 and Isl1 (show ISL1 ELISA Kits), are sufficient to specify the retinal ganglion cell fate in ATOH7 (show ATOH7 ELISA Kits) deficient mice

  5. Increased Brn-3b and p53 (show TP53 ELISA Kits) correlated with elevated expression of pro-apoptotic target genes, Bax (show BAX ELISA Kits), Noxa (show PMAIP1 ELISA Kits) and PUMA (show BBC3 ELISA Kits), whereas cleaved caspase-3 (show CASP3 ELISA Kits) confirmed the presence of apoptotic cells within this region of the injured heart.

  6. Study demonstrates a sequential expression order of NEUROD1 (show NEUROD1 ELISA Kits)>ISL1 (show ISL1 ELISA Kits)>POU4F1 (show POU4F1 ELISA Kits)>POU4F2 during the inner ear neurogenesis.

  7. Pou4f1 (show POU4F1 ELISA Kits) and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

  8. Isl1 (show ISL1 ELISA Kits) and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

  9. Data indicate that Brn3 (show POU4F1 ELISA Kits) transcription factors Brn3b affects Brn3a (show POU4F1 ELISA Kits) and Brn3c (show POU4F3 ELISA Kits) positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  10. Brn3b is expressed in a subset of intrinsically photosensitive retinal ganglion cells

POU4F2 Antigen Profile

Antigen Summary

member of the POU family of transcription factors\\\\; play key roles in the development of specific neuronal cell types

Gene names and symbols associated with POU4F2

  • POU class 4 homeobox 2 (Pou4f2) antibody
  • POU domain, class 4, transcription factor 2 (pou4f2) antibody
  • POU class 4 homeobox 2 (pou4f2) antibody
  • POU domain, class 4, transcription factor 2 (POU4F2) antibody
  • POU class 4 homeobox 2 (POU4F2) antibody
  • POU domain, class 4, transcription factor 2 (po4f2) antibody
  • POU domain, class 4, transcription factor 2 (Pou4f2) antibody
  • Brn-3.2 antibody
  • Brn-3b antibody
  • BRN3.2 antibody
  • BRN3B antibody
  • brn3b-A antibody
  • mBrn3-3R antibody
  • Pou4f-rs1 antibody
  • POU4F2 antibody
  • Xbrn3b antibody

Protein level used designations for POU4F2

POU domain, class 4, transcription factor 2 , brn3b , pou4f2/brn-3b , POU-homeodomain protein , POU class 4 homeobox 2 , Brn3b POU domain transcription factor , POU domain class 4 transcription factor 2 , POU domain protein , brain-3B , brain-specific homeobox/POU domain protein 3B , POU domain, class 4, transcription factor, related sequence 1

GENE ID SPECIES
171355 Rattus norvegicus
402816 Danio rerio
378524 Xenopus laevis
428735 Gallus gallus
374085 Gallus gallus
471317 Pan troglodytes
100306795 Salmo salar
5458 Homo sapiens
482637 Canis lupus familiaris
532453 Bos taurus
18997 Mus musculus
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