You are viewing an incomplete version of our website. Please click to reload the website as full version.

POU Domain, Class 4, Transcription Factor 2 Proteins (POU4F2)

member of the POU family of transcription factors\\\\; play key roles in the development of specific neuronal cell types [RGD, Feb 2006].. Additionally we are shipping POU4F2 Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat POU4F2 POU4F2 171355  
POU4F2 5458 Q12837
POU4F2 18997 Q63934
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top POU4F2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

POU4F2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for POU Domain, Class 4, Transcription Factor 2 (POU4F2) Interaction Partners

Zebrafish POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. The cloning and expression profile of brn-3b in the zebrafish (Danio rerio) were assessed as the first step for understanding its role in the development of sensory systems.

Human POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. The genes BCL6, NFE2, POU4F2 and ELF4 are primary 1,25(OH)2D3 targets in THP-1 cells

  2. Methylation levels of EOMES, HOXA9, POU4F2, TWIST1, VIM, and ZNF154 in urine specimens are promising diagnostic biomarkers for bladder cancer recurrence surveillance

  3. Levels of CDK4 (show CDK4 Proteins) mRNA and protein correlate with levels of Brn-3b in breast cancer cell lines manipulated to express different levels of Brn-3b and in human breast cancer biopsies; Brn-3b can activate the CDK4 (show CDK4 Proteins) promoter

  4. Brn-3b transcription factor contributes to proliferation of neuroblastoma (show ARHGEF16 Proteins) cells in vivo and in vitro but may also influence progression and/or invasion during tumorigenesis.

  5. Brn-3b can, directly and indirectly (via interaction with the ER), activate HSP-27 (show HSPB1 Proteins) expression, and this may represent one mechanism by which Brn-3b mediates its effects in breast cancer cells.

  6. Brn-3b expression has been shown to be a prerequisite for developmental survival of most retinal ganglion cells.

  7. first time that a Brn-3b POU family transcription factor has been shown to regulate a member of the catenin family, which provides insight into the molecular mechanisms by which Brn-3b expression may favour breast cancer progression and tumor invasion

  8. Two different microRNAs that potentially regulate the stability of Brn-3b have been identified in neuroblastoma (show ARHGEF16 Proteins) cells.

  9. May act to alter growth properties of breast cancer and neuroblastoma (show ARHGEF16 Proteins) cells by enhancing cyclin D1 (show CCND1 Proteins) expression in these tumor cells.

  10. Brn3b specifies the RGC fate from multipotential precursors not only by promoting RGC differentiation but also by suppressing non-RGC differentiation programs as a safeguard mechanism.

Mouse (Murine) POU Domain, Class 4, Transcription Factor 2 (POU4F2) interaction partners

  1. Pou4f2 KO mice exhibit profound hyperglycemia, increased GSK3B expression, and decreased GLUT4 (show SLC2A4 Proteins) expression. In C2C12 myocytes, Pou4f2 mRNA and protein are induced by glucose and inhibited by insulin (show INS Proteins).

  2. Results suggest the existence of a coordinated mechanism by miR (show MLXIP Proteins)-23a and miR (show MLXIP Proteins)-374 to down regulate Brn3b and ultimately regulate the development of retinal ganglion cells from their precursors

  3. Pou4f2 and Isl1 (show ISL1 Proteins), are sufficient to specify the retinal ganglion cell fate in ATOH7 (show ATOH7 Proteins) deficient mice

  4. Increased Brn-3b and p53 (show TP53 Proteins) correlated with elevated expression of pro-apoptotic target genes, Bax (show BAX Proteins), Noxa (show PMAIP1 Proteins) and PUMA (show BBC3 Proteins), whereas cleaved caspase-3 (show CASP3 Proteins) confirmed the presence of apoptotic cells within this region of the injured heart.

  5. Study demonstrates a sequential expression order of NEUROD1 (show NEUROD1 Proteins)>ISL1 (show ISL1 Proteins)>POU4F1 (show POU4F1 Proteins)>POU4F2 during the inner ear neurogenesis.

  6. Pou4f1 (show POU4F1 Proteins) and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

  7. Isl1 (show ISL1 Proteins) and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

  8. Data indicate that Brn3 (show POU4F1 Proteins) transcription factors Brn3b affects Brn3a (show POU4F1 Proteins) and Brn3c (show POU4F3 Proteins) positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  9. Brn3b is expressed in a subset of intrinsically photosensitive retinal ganglion cells

  10. Brn-3b suppresses the role of DLX1/2 through physical interaction and biases the competent precursors toward retinal ganglion cell fates.

POU4F2 Protein Profile

Protein Summary

member of the POU family of transcription factors\\\\; play key roles in the development of specific neuronal cell types

Gene names and symbols associated with POU4F2

  • POU class 4 homeobox 2 (Pou4f2)
  • POU domain, class 4, transcription factor 2 (pou4f2)
  • POU class 4 homeobox 2 (pou4f2)
  • POU domain, class 4, transcription factor 2 (POU4F2)
  • POU class 4 homeobox 2 (POU4F2)
  • POU domain, class 4, transcription factor 2 (po4f2)
  • POU domain, class 4, transcription factor 2 (Pou4f2)
  • Brn-3.2 protein
  • Brn-3b protein
  • BRN3.2 protein
  • BRN3B protein
  • brn3b-A protein
  • mBrn3-3R protein
  • Pou4f-rs1 protein
  • POU4F2 protein
  • Xbrn3b protein

Protein level used designations for POU4F2

POU domain, class 4, transcription factor 2 , brn3b , pou4f2/brn-3b , POU-homeodomain protein , POU class 4 homeobox 2 , Brn3b POU domain transcription factor , POU domain class 4 transcription factor 2 , POU domain protein , brain-3B , brain-specific homeobox/POU domain protein 3B , POU domain, class 4, transcription factor, related sequence 1

GENE ID SPECIES
171355 Rattus norvegicus
402816 Danio rerio
378524 Xenopus laevis
428735 Gallus gallus
374085 Gallus gallus
471317 Pan troglodytes
100306795 Salmo salar
5458 Homo sapiens
482637 Canis lupus familiaris
532453 Bos taurus
18997 Mus musculus
Selected quality suppliers for POU4F2 Proteins (POU4F2)
Did you look for something else?