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POU Domain, Class 4, Transcription Factor 3 (POU4F3) ELISA Kits

POU4F3 encodes a member of the POU-domain family of transcription factors. Additionally we are shipping POU4F3 Antibodies (56) and POU4F3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human POU4F3 POU4F3 5459 Q15319
Anti-Rat POU4F3 POU4F3 364855  
Anti-Mouse POU4F3 POU4F3 18998 Q63955
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More ELISA Kits for POU4F3 Interaction Partners

Human POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. The pou4f3 gene is regulated by ATOH1 (show ATOH1 ELISA Kits) and other transcription factors in cochlear hair cells.

  2. These data demonstrate that Nr2f2 (show NR2F1 ELISA Kits) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  3. new variants in genes such as POU4F3 is associated with nonsyndromic deafness and vestibular dysfunction

  4. SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15).

  5. This is the first report of a POU4F3 mutation in Asia, and moreover our data suggest that further investigation will need to delineate ethnicity-specific genetic background for autosomal dominant non-syndromic hearing loss within Asian populations.

  6. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family H members.

  7. Data show that Brn-3c is capable of activating both BDNF (show BDNF ELISA Kits) and NT-3 (show NTF3 ELISA Kits) promoters in inner ear sensory epithelial cell lines.

  8. our data show there are common sequence variants in the Brn-3c 5'-flanking region that affect transcriptional regulation in vitro

  9. Mutation analysis of the POU4F3 gene in 30 patients suffering from dominantly inherited hearing impairment revealed a second novel missense mutation (c.668T>C).

  10. report presents a detailed audiometric analysis of a Dutch family linked to DFNA15 with a novel mutation (p.L289F) in the POU4F3 gene

Mouse (Murine) POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. These data demonstrate that Nr2f2 (show NR2F2 ELISA Kits) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  2. Data indicate that Brn3 (show POU4F1 ELISA Kits) transcription factors Brn3b (show POU4F2 ELISA Kits) affects Brn3a (show POU4F1 ELISA Kits) and Brn3c positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  3. induction of POU4F3 by TFE2 and GATA3 (show GATA3 ELISA Kits)

  4. neither Brn3a (show POU4F1 ELISA Kits) nor Brn3c are expressed in intrinsically photosensitive retinal ganglion cells

  5. Data show that Ap-2delta occupies and activates the Pou4f3 and Bhlhb4 (show BHLHE23 ELISA Kits) promoters.

  6. Stress-granule-associated protein Caprin-1 is downregulated by Pou4f3.

  7. Taken together, our data suggest that SHH (show SHH ELISA Kits) plays an important role in the promotion of auditory hair cell differentiation via the Math1 (show ATOH1 ELISA Kits)-Brn3.1 signaling pathway.

  8. Brn3c null mice show severe compromised production of these neurotrophins and should therefore show a comparable pattern of nerve fiber loss.

  9. Brn-3c was found to contain an independent N-terminal activation domain that is sufficient to activate gene transcription in the organ-of-Corti-derived cell lines.

  10. Inner hair cells constitutively express alpha9alpha10 nicotinic cholinergic receptors into adulthood by expressing the alpha10 cDNA under the control of the Pou4f3 gene promoter.

POU4F3 Antigen Profile

Antigen Summary

This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.

Gene names and symbols associated with POU4F3

  • POU class 4 homeobox 3 (POU4F3) antibody
  • POU class 4 homeobox 3 (Pou4f3) antibody
  • POU domain, class 4, transcription factor 3 (pou4f3) antibody
  • POU domain, class 4, transcription factor 3 (Pou4f3) antibody
  • BRN-3 antibody
  • BRN-3.1 antibody
  • brn-3c antibody
  • BRN3 antibody
  • Brn3.1 antibody
  • Brn3c antibody
  • ddl antibody
  • DFNA15 antibody
  • dreidel antibody
  • POU4F3 antibody

Protein level used designations for POU4F3

POU class 4 homeobox 3 , POU domain, class 4, transcription factor 3 , brain-3 , brain-specific homeobox/POU domain protein 3 , brain-3C , brain-specific homeobox/POU domain protein 3C , brn-3C , brain POU domain gene 3.1 , brain-3.1 , brain-specific homeobox/POU domain protein 3.1 , zfbrn-3.1 , brain-specific homeobox POU domain protein 3C

GENE ID SPECIES
471685 Pan troglodytes
395521 Gallus gallus
5459 Homo sapiens
487200 Canis lupus familiaris
100510953 Sus scrofa
538520 Bos taurus
364855 Rattus norvegicus
30534 Danio rerio
18998 Mus musculus
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