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anti-PR Domain Containing 2, with ZNF Domain (PRDM2) Antibodies

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. Additionally we are shipping PRDM2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRDM2 7799 Q13029
PRDM2 110593  
PRDM2 313678 Q63755
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Top anti-PRDM2 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), IP, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ChIP, WB Western blot analysis of anti-PRDM2 Mab (ABIN387783) in lysate from tr... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p) A) Rat B50 brain tumor cell extracts were immunoprecipitated with RIZ ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human PRDM2 in human astrocytoma with rabbi... Immunochemical staining of human PRDM2 in human glioblastoma with rabb... 100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4... Formalin-fixed and paraffin-embedded rat brain labeled with Anti-KMT8/... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IF, IP Immunoprecipitation of RIZ from MCF7 cells with mouse IgG2b or K0183-3... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Alkaline Phosphatase (AP) IP, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IP, WB 400 μL Log in to see 6 Days
$457.14
Details

PRDM2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,

Top referenced anti-PRDM2 Antibodies

  1. Human Polyclonal PRDM2 Primary Antibody for ELISA - ABIN1998489 : Shapiro, Lee, Winoto: Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3. in Gene 1995 (PubMed)
    Show all 5 references for ABIN1998489

  2. Human Monoclonal PRDM2 Primary Antibody for ChIP, WB - ABIN387783 : Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. in Journal of hematology & oncology 2009 (PubMed)
    Show all 2 references for ABIN387783

  3. Human Polyclonal PRDM2 Primary Antibody for EIA, IHC (p) - ABIN356710 : Muraosa, Takahashi, Yoshizawa, Shibahara: cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. in European journal of biochemistry / FEBS 1996 (PubMed)
    Show all 2 references for ABIN356710

More Antibodies against PRDM2 Interaction Partners

Human PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. RIZ1 expression is negatively correlated with glioma differentiation and can serve as a predictor of glioma prognosis and thus could be a potential therapeutic target for patients with gliomas.

  2. Loss of RIZ1 expression due to methylation is associated with Renal Cell Carcinoma (show MOK Antibodies).

  3. PRDM2 downregulation may play a role in dopamine-agonist resistance and tumor recurrence in prolactinomas.

  4. Results suggest that high expression of SMYD3 (show SMYD3 Antibodies) is related to the occurrence of esophageal squamous cell carcinoma. Also, its suppression promoted the expression of RIZ1 suggesting a signal transduction pathway between SMYD3 (show SMYD3 Antibodies) and RIZ1.

  5. PRDM2, PRDM5 (show PRDM5 Antibodies), PRDM16 (show PRDM16 Antibodies) promoters are methylated and their expression is suppressed in lung cancer cells.

  6. The development and progression of esophageal squamous cell carcinoma are related to the inactivation of RIZ1.

  7. RIZ1 expression is significantly downregulated as the formation of meningiomas progressed, and suggest that RIZ1 may represent a promising candidate tumor suppressor gene that contributes to malignant meningiomas.

  8. Reduction of RIZ1 expression aggravates the progression of liver fluke-related cholangiocarcinoma

  9. Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype

  10. Data suggest that promoter methylation may play an important role in the epigenetic silencing of RIZ1 gene expression in human esophageal squamous cell carcinoma.

Mouse (Murine) PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. RIZ1 might participate osteoclast formation through the regulation of NFATc1 (show NFATC1 Antibodies) expression.

  2. Data suggest that the histone methyltransferase RIZ1 is required for estrogen response in female reproductive tissues and that estrogen-bound estrogen receptors may turn a transcriptional repressor into a coactivator.

PRDM2 Antigen Profile

Protein Summary

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PRDM2

  • PR domain containing 2, with ZNF domain (prdm2) antibody
  • PR domain containing 2, with ZNF domain b (prdm2b) antibody
  • PR domain containing 2, with ZNF domain (PRDM2) antibody
  • similar to zinc finger protein RIZ (PRDM2) antibody
  • PR domain containing 2, with ZNF domain (Prdm2) antibody
  • 4833427P12Rik antibody
  • E330024L24Rik antibody
  • Gm1033 antibody
  • Gm19732 antibody
  • HUMHOXY1 antibody
  • KMT8 antibody
  • MGC114763 antibody
  • MTB-ZF antibody
  • PRDM2 antibody
  • Riz antibody
  • Riz1 antibody
  • RIZ2 antibody
  • Znfpr1c1 antibody

Protein level used designations for PRDM2

PR domain containing 2, with ZNF domain , retinoblastoma protein-binding zinc finger protein-like , PR domain zinc finger protein 2-like , GATA-3 binding protein G3B , GATA-3-binding protein G3B , MTE-binding protein , PR domain zinc finger protein 2 , PR domain-containing protein 2 , lysine N-methyltransferase 8 , retinoblastoma protein-binding zinc finger protein , retinoblastoma protein-interacting zinc finger protein , zinc finger protein RIZ , zinc-finger DNA-binding protein , retinoblastoma interacting zinc finger protein

GENE ID SPECIES
494709 Xenopus laevis
797296 Danio rerio
100170624 Xenopus (Silurana) tropicalis
100350859 Oryctolagus cuniculus
100385110 Callithrix jacchus
100436958 Pongo abelii
100010516 Monodelphis domestica
469125 Pan troglodytes
100481446 Ailuropoda melanoleuca
100582767 Nomascus leucogenys
7799 Homo sapiens
110593 Mus musculus
313678 Rattus norvegicus
419478 Gallus gallus
100688431 Canis lupus familiaris
789222 Bos taurus
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