PR Domain Containing 2, with ZNF Domain (PRDM2) ELISA Kits

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. Additionally we are shipping PRDM2 Antibodies (73) and PRDM2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PRDM2 PRDM2 7799 Q13029
Anti-Mouse PRDM2 PRDM2 110593  
Anti-Rat PRDM2 PRDM2 313678 Q63755
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More ELISA Kits for PRDM2 Interaction Partners

Human PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. Promoter region methylation of RIZ1 may play an important role in the epigenetic silencing of RIZ1 expression in pituitary adenomas, which may translate into important diagnostic and therapeutic applications

  2. RIZ1 expression is negatively correlated with glioma differentiation and can serve as a predictor of glioma prognosis and thus could be a potential therapeutic target for patients with gliomas.

  3. Loss of RIZ1 expression due to methylation is associated with Renal Cell Carcinoma.

  4. PRDM2 downregulation may play a role in dopamine-agonist resistance and tumor recurrence in prolactinomas.

  5. Results suggest that high expression of SMYD3 (show SMYD3 ELISA Kits) is related to the occurrence of esophageal squamous cell carcinoma. Also, its suppression promoted the expression of RIZ1 suggesting a signal transduction pathway between SMYD3 (show SMYD3 ELISA Kits) and RIZ1.

  6. PRDM2, PRDM5 (show PRDM5 ELISA Kits), PRDM16 (show PRDM16 ELISA Kits) promoters are methylated and their expression is suppressed in lung cancer cells.

  7. The development and progression of esophageal squamous cell carcinoma are related to the inactivation of RIZ1.

  8. RIZ1 expression is significantly downregulated as the formation of meningiomas progressed, and suggest that RIZ1 may represent a promising candidate tumor suppressor gene that contributes to malignant meningiomas.

  9. Reduction of RIZ1 expression aggravates the progression of liver fluke-related cholangiocarcinoma

  10. Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype

Mouse (Murine) PR Domain Containing 2, with ZNF Domain (PRDM2) interaction partners

  1. RIZ1 is an important regulator of both Akt3 (show AKT3 ELISA Kits) transcription and AKT (show AKT1 ELISA Kits) phosphorylation and suggest a role for RIZ1 in HF-induced obesity and the AKT (show AKT1 ELISA Kits) pathway

  2. RIZ1 might participate osteoclast formation through the regulation of NFATc1 (show NFATC1 ELISA Kits) expression.

  3. Data suggest that the histone methyltransferase RIZ1 is required for estrogen response in female reproductive tissues and that estrogen-bound estrogen receptors may turn a transcriptional repressor into a coactivator.

PRDM2 Antigen Profile

Antigen Summary

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PRDM2

  • PR domain containing 2, with ZNF domain (prdm2) antibody
  • PR domain containing 2, with ZNF domain b (prdm2b) antibody
  • PR domain containing 2, with ZNF domain (PRDM2) antibody
  • similar to zinc finger protein RIZ (PRDM2) antibody
  • PR domain containing 2, with ZNF domain (Prdm2) antibody
  • 4833427P12Rik antibody
  • E330024L24Rik antibody
  • Gm1033 antibody
  • Gm19732 antibody
  • HUMHOXY1 antibody
  • KMT8 antibody
  • MGC114763 antibody
  • MTB-ZF antibody
  • PRDM2 antibody
  • Riz antibody
  • Riz1 antibody
  • RIZ2 antibody
  • Znfpr1c1 antibody

Protein level used designations for PRDM2

PR domain containing 2, with ZNF domain , retinoblastoma protein-binding zinc finger protein-like , PR domain zinc finger protein 2-like , GATA-3 binding protein G3B , GATA-3-binding protein G3B , MTE-binding protein , PR domain zinc finger protein 2 , PR domain-containing protein 2 , lysine N-methyltransferase 8 , retinoblastoma protein-binding zinc finger protein , retinoblastoma protein-interacting zinc finger protein , zinc finger protein RIZ , zinc-finger DNA-binding protein , retinoblastoma interacting zinc finger protein

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100170624 Xenopus (Silurana) tropicalis
100350859 Oryctolagus cuniculus
100385110 Callithrix jacchus
100436958 Pongo abelii
100010516 Monodelphis domestica
469125 Pan troglodytes
100481446 Ailuropoda melanoleuca
100582767 Nomascus leucogenys
7799 Homo sapiens
110593 Mus musculus
313678 Rattus norvegicus
419478 Gallus gallus
100688431 Canis lupus familiaris
789222 Bos taurus
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