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PR Domain Containing 6 (PRDM6) ELISA Kits

Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Additionally we are shipping PRDM6 Antibodies (29) and PRDM6 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat PRDM6 PRDM6 307305  
Anti-Human PRDM6 PRDM6 93166 Q9NQX0
Anti-Mouse PRDM6 PRDM6 225518 Q3UZD5
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More ELISA Kits for PRDM6 Interaction Partners

Human PR Domain Containing 6 (PRDM6) interaction partners

  1. Three novel loci were identified in East Asians with cardiac arrhythmias: rs2483280 (PRDM16 (show PRDM16 ELISA Kits) locus) and rs335206 (PRDM6 locus) were associated with QRS (show QARS ELISA Kits) duration; and rs17026156 (SLC8A1 (show SLC8A1 ELISA Kits) locus) correlated with PR interval.

Mouse (Murine) PR Domain Containing 6 (PRDM6) interaction partners

  1. identified Prdm6 as a factor that is essential for the physiological control of cardiovascular development

  2. PRISM acts as a novel epigenetic regulator of Smooth Muscle Cells (SMC (show DYM ELISA Kits)) phenotypic plasticity by suppressing differentiation and maintaining the proliferative potential of vascular SMCs.

  3. These data indicate that PRDM6 is expressed by vascular precursors, has differential effects in endothelial cells and smooth muscle cells, and may play a role in vascular precursor differentiation and survival.

PRDM6 Antigen Profile

Antigen Summary

Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

Gene names and symbols associated with PRDM6

  • PR domain containing 6 (Prdm6) antibody
  • PR domain containing 6 (PRDM6) antibody
  • PR domain containing 6 (prdm6) antibody
  • PR domain containing 6 (LOC100354345) antibody
  • Gm92 antibody
  • PRDM6 antibody
  • PRISM antibody
  • RGD1559594 antibody

Protein level used designations for PRDM6

PR domain containing 6 , PR domain zinc finger protein 6 , PR domain-containing protein 6 , PR-domain zinc finger protein 6 , putative histone-lysine N-methyltransferase PRDM6 , PR domain-containing protein in smooth muscle

GENE ID SPECIES
307305 Rattus norvegicus
426800 Gallus gallus
742318 Pan troglodytes
100169948 Danio rerio
100354345 Oryctolagus cuniculus
100579681 Nomascus leucogenys
93166 Homo sapiens
225518 Mus musculus
519857 Bos taurus
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