PRKC, Apoptosis, WT1, Regulator (PAWR) ELISA Kits

The tumor suppressor WT1 represses and activates transcription. Additionally we are shipping PAWR Antibodies (64) and PAWR Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PAWR 5074 Q96IZ0
PAWR 64513 Q62627
PAWR 114774 Q925B0
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Top PAWR ELISA Kits at

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
  96 Tests Log in to see 2 to 3 Days

More ELISA Kits for PAWR Interaction Partners

Human PRKC, Apoptosis, WT1, Regulator (PAWR) interaction partners

  1. Data suggest that PAR4 and P2Y12 (show P2RY12 ELISA Kits) heterodimer internalization/endocytosis is required for beta-arrestin-2 (show ARRB2 ELISA Kits) recruitment to endosomes and up-regulation of Akt (show AKT1 ELISA Kits) signaling; activation of PAR4 but not of P2Y12 (show P2RY12 ELISA Kits) drives internalization of the PAR4-P2Y12 (show P2RY12 ELISA Kits) heterodimer. (PAR4 = protease-activated receptor 4 (show F2RL3 ELISA Kits); P2Y12 (show P2RY12 ELISA Kits) = purinergic receptor P2Y (show P2RY1 ELISA Kits), G-protein coupled, 12 protein; Akt (show AKT1 ELISA Kits) = proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-akt (show AKT1 ELISA Kits))

  2. In this review, we will focus on the therapeutic perspective of Par-4 with a special reference to its (Par-4) virgin prospect of devastating metastasis control.

  3. in vitro and in vivo upregulation of Par-4 expression is indispensable for the trafficking of GRP78 (show HSPA5 ELISA Kits) to the cell membrane and subsequent apoptosis of cancer cell

  4. Prostate apoptosis response 4 (PAR4) expression modulates WNT (show WNT2 ELISA Kits) signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity.

  5. Decreased PAR4 expression in breast cancer is associated with shorter survival. PAR4 suppresses growth and invasiveness of breast cancer cells.

  6. Authors determined that PAR-4 induces cell apoptosis in response to stimuli, in vitro, but is also involved in the relocation of GRP78 (show HSPA5 ELISA Kits) from endoplasmic reticulum to the cell surface of ovarian cancer cell line.

  7. These results suggest that Porphyromonas gingivalis activates PAR4 signaling pathways, leading proMMP9 over-expression and cellular invasion in oral squamous cell carcinoma cells.

  8. PAR1 (show MARK2 ELISA Kits)-platelet releasate enhances vasculogenesis more potently than PAR4-platelet releasate, and the enhancements require a cooperation of multiple platelet-derived angiogenic regulators.

  9. A novel long non-coding RNA T-ALL-R-LncR1 knockdown and Par-4 cooperate to induce cellular apoptosis in T-cell acute lymphoblastic leukemia cells.

  10. Data indicate that PAR1 (show MARK2 ELISA Kits) and PAR4 activate common promigratory signalling pathways in Hep3B liver carcinoma cells including activation of the receptor tyrosine kinases Met and PDGFR (show PDGFRB ELISA Kits), the formation of ROS (show ROS1 ELISA Kits) and the inactivation of PTP1B (show PTPN1 ELISA Kits).

Mouse (Murine) PRKC, Apoptosis, WT1, Regulator (PAWR) interaction partners

  1. Findings reveal a novel role for Par-4 (show F2RL3 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) in islet beta cell apoptosis and type 2 diabetes.

  2. Par4 (show F2RL3 ELISA Kits), CEBPB (show CEBPB ELISA Kits) and FAK (show PTK2 ELISA Kits) form a senescence signaling pathway, playing roles in modulating cell survival, growth, apoptosis, EMT (show ITK ELISA Kits) and self-renewal

  3. a novel mechanism of apoptosis induction by PAR-4 (show F2RL3 ELISA Kits)/ceramide-enriched exosomes, which may critically contribute to Alzheimer disease.

  4. extracellular Par-4 (show F2RL3 ELISA Kits)/SAC (show ADCY10 ELISA Kits) is systemically functional in inhibition of tumor growth and metastasis progression.

  5. loss of PAR4 (show F2RL3 ELISA Kits) leads to a reduction in the ability of tumour necrosis factor-alpha (show TNF ELISA Kits) to induce apoptosis by increased activation of NF-kappaB (show NFKB1 ELISA Kits)

  6. Antisense knockdown of PAR-4 (show F2RL3 ELISA Kits) or inhibition of ceramide biosynthesis reduced stem cell apoptosis; PAR-4 (show F2RL3 ELISA Kits) overexpression and treatment with ceramide analogs elevated apoptosis.

  7. AATF (show AATF ELISA Kits) is an endogenous antagonist of Par-4 (show F2RL3 ELISA Kits) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  8. Par-4 (show F2RL3 ELISA Kits) is directly involved in regulating choline uptake by interacting with CHT1 (show ChT ELISA Kits) and by reducing its incorporation on the cell surface

  9. the mechanism for Ras-mediated down-regulation of Par-4 (show F2RL3 ELISA Kits) is by promoter methylation

  10. direct physical association with ceramide and PAR-4 (show F2RL3 ELISA Kits) regulates the activity of PKCzeta (show PRKCZ ELISA Kits)

PAWR Antigen Profile

Antigen Summary

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Gene names and symbols associated with PAWR

  • PRKC, apoptosis, WT1, regulator (PAWR) antibody
  • PRKC, apoptosis, WT1, regulator (pawr) antibody
  • PRKC, apoptosis, WT1, regulator (Pawr) antibody
  • 2310001G03Rik antibody
  • MGC81382 antibody
  • Par-4 antibody
  • Par4 antibody
  • PAWR antibody
  • pawrl antibody
  • zgc:103513 antibody

Protein level used designations for PAWR

PRKC, apoptosis, WT1, regulator , PAR-4 , PRKC apoptosis WT1 regulator protein , PRKC, apoptosis, WT1, regulator like , WT1-interacting protein , prostate apoptosis response 4 protein , prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , prostate apoptosis response-4 , transcriptional repressor PAR4 , Prostate apoptosis response protein 4 , par-4 induced by effectors of apoptosis , transcriptional repressor Par-4-like protein PAWR

417870 Gallus gallus
447443 Xenopus laevis
449994 Danio rerio
452094 Pan troglodytes
532789 Bos taurus
695617 Macaca mulatta
5074 Homo sapiens
64513 Rattus norvegicus
114774 Mus musculus
611487 Canis lupus familiaris
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