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PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) Proteins (PRPF3)

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. Additionally we are shipping PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRPF3 9129 O43395
Rat PRPF3 PRPF3 361995  
PRPF3 70767 Q922U1
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Top PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
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HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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PRPF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) (PRPF3) Interaction Partners

Human PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) (PRPF3) interaction partners

  1. RP-PRPF defects affect the stoichiometry of spliceosomal small nuclear RNAs. Mutant PRPF3 proteins stably associated with tri (show VANGL2 Proteins)-snRNPs.

  2. A mutation in the PRPF3 gene is rare compared to other genes causing autosomal dominant retinitis pigmentosa.

  3. The human HPRP3 gene, the orthologue of the yeast pre-mRNA splicing factor (PRP3)

  4. role in the recruitment of Hprp4p for the U4/U6 snRNP (show LSM2 Proteins) assembly

  5. Nine mutations, six of which are novel, in the pre-mRNA splicing-factor (show SNRPB Proteins) genes PRPF3, PRPF8, and PRPF31 (show PRPF31 Proteins), causing adRP (show PLIN2 Proteins) have been identified in the Spanish population.

  6. Free and complexed cyclophilin H (show PPIH Proteins) have virtually identical conformations suggesting that the U4/U6-60K binding site is pre-shaped and the peptidyl-prolyl-cis/trans isomerase (show PPIL1 Proteins) activity is unaffected by complex formation

  7. We conclude that the Thr494Met mutation in the HPRP3 gene causes ADRP (show PLIN2 Proteins) in Japanese patients. This mutation was found in 1% of patients with ADRP (show PLIN2 Proteins) in Japan

  8. PAP-1 interacted with Prp3p but not Prp31p in human cells and yeast, and the basic region of PAP-1 and the C-terminal region of Prp3p, regions beside spots found in retinitis pigmentosa mutations, were needed for binding

  9. splicing factor (show SLU7 Proteins) PRPF3 mutations cause retinal degeneration and form detrimental aggregates in photoreceptor cells

  10. Findings suggest that the loss of Hprp3p phosphorylation at Thr494 is a key step for initiating Thr494Met aberrant interactions within U4/U6 snRNP (show LSM2 Proteins) complex and these are likely linked to the retinitis pigmentosa type 18 phenotype.

Pig (Porcine) PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) (PRPF3) interaction partners

  1. Swine PRPF3 gene has a closer genetic relationship with the PRPF3 gene of sumatran orangutan.

Mouse (Murine) PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) (PRPF3) interaction partners

  1. The mouse retinal pigment epithelium (RPE (show RPE Proteins))is the primary cell affected by mutations in the RNA splicing factors (PRPF3, PRPF8, and PRPF31 (show PRPF31 Proteins)), and these changes occur at an early age.

  2. analyzed the spatial and temporal expression of the PRPF3 gene in mice and found that it is highly expressed in retinal cells relative to other tissues and its expression is developmentally regulated

  3. The finding of similar degenerative changes in RPE (show RPE Proteins) cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor (show SLU7 Proteins) forms of retinitis pigmentosa.

  4. TASP1 (show TASP1 Proteins), EPS15R, and PRPF3 expression were significantly induced in HCCs (show HCCS Proteins) of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha (show HNF4A Proteins)

PRP3 Pre-MRNA Processing Factor 3 Homolog (S. Cerevisiae) (PRPF3) Protein Profile

Protein Summary

The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.

Gene names and symbols associated with PRPF3

  • PRP3 pre-mRNA processing factor 3 homolog (yeast) (prpf3)
  • PRP3 pre-mRNA processing factor 3 homolog (PRPF3)
  • PRP3 pre-mRNA processing factor 3 homolog (LOC100221159)
  • pre-mRNA processing factor 3 (prpf3)
  • pre-mRNA processing factor 3 (PRPF3)
  • pre-mRNA processing factor 3 (Prpf3)
  • PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) (PRPF3)
  • PRP3 pre-mRNA processing factor 3 homolog (yeast) (Prpf3)
  • 3632413F13Rik protein
  • HPRP3 protein
  • HPRP3P protein
  • PRP3 protein
  • Prp3p protein
  • PRPF3 protein
  • RP18 protein
  • SNRNP90 protein
  • wu:fa11f05 protein

Protein level used designations for PRPF3

U4/U6 small nuclear ribonucleoprotein Prp3 , U4/U6-associated RNA splicing factor , PRP3 pre-mRNA processing factor 3 homolog , U4/U6 snRNP 90 kDa protein , pre-mRNA-splicing factor 3 , pre-mRNA processing factor 3-like protein

GENE ID SPECIES
403072 Danio rerio
706898 Macaca mulatta
100221159 Taeniopygia guttata
443589 Xenopus laevis
9129 Homo sapiens
361995 Rattus norvegicus
426667 Gallus gallus
100190995 Sus scrofa
510322 Bos taurus
100440626 Pongo abelii
70767 Mus musculus
475836 Canis lupus familiaris
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