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anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Antibodies

PRPF31 encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. Additionally we are shipping PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRPF31 26121 Q8WWY3
PRPF31 292536  
PRPF31 68988 Q8CCF0
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Top anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated EIA, WB AP20107PU-N PRPF31 Antibody staining (0.3 µg/ml) of cell line A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334465 (1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB PRPF31 Antibody (C-term) (ABIN658463) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the PRPF31 antibody detected the PRPF31 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of PRPF31 expression in transfected 293T cell line by PRPF31 monoclonal antibody (M02), clone 8E1.Lane 1: PRPF31 transfected lysate(55.5 KDa).Lane 2: Non-transfected lysate. PRPF31 monoclonal antibody (M02), clone 8E1. Western Blot analysis of PRPF31 expression in human liver. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB PRPF31 polyclonal antibody (A01), Lot # 060619JCS1 Western Blot analysis of PRPF31 expression in HeLa . Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using PRP31 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

PRPF31 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies

  1. Human Polyclonal PRPF31 Primary Antibody for ELISA, WB - ABIN565227 : Nag, Steitz: Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicing. in RNA biology 2012 (PubMed)

  2. Dog (Canine) Polyclonal PRPF31 Primary Antibody for EIA, WB - ABIN498020 : Makarova, Makarov, Liu, Vornlocher, Lührmann: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. in The EMBO journal 2002 (PubMed)

  3. Human Monoclonal PRPF31 Primary Antibody for ELISA, WB - ABIN949177 : Adler, McCleland, Yee, Yaylaoglu, Hussain, Cosino, Quinones, Modrusan, Seshagiri, Torres, Chopra, Haley, Zhang, Blackwood, Singh, Junttila, Stephan, Liu, Pau, Fearon, Jiang, Firestein: An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. in Genes & development 2014 (PubMed)

  4. Human Polyclonal PRPF31 Primary Antibody for ELISA, WB - ABIN334465 : Yuan, Kawada, Havlioglu, Tang, Wu: Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)

More Antibodies against PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Interaction Partners

Human PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. As PRPF31 mutations cause retinitis pigmentosa by haploinsufficiency, this is a good candidate for adeno (show ADORA2A Antibodies)-associated virus (AAV)-based gene augmentation therapy.

  2. A PRPF31 mutation was identified to be responsible for adRP (show PLIN2 Antibodies) in a large Chinese family. Our findings expand the mutation spectrum of RP in the Chinese population.

  3. A mutation in PRPF31 is hypostatic to a trait acting on CNOT3 (show CNOT3 Antibodies), with the RP11 phenotype only being observed when there is homozygous (recessive) inheritance of the higher expressivity CNOT3 (show CNOT3 Antibodies) ("symptomatic" or risk) allele.

  4. identification of the novel "A" insertion mutation in exon9 at chr19:54629961-54629961 in PRPF31 can provide further genetic evidence for clinical test for adRP (show PLIN2 Antibodies) and JMD.

  5. Two novel PRPF31 mutations including a complex insertion-deletion mutation have been identified in Chinese families with retinitis pigmentosa.

  6. We have identified a novel 14-bp deletion in PRPF31 as the genetic driver of adRP (show PLIN2 Antibodies) in a large Mexican family that exhibits nonpenetrance and variable expressivity, known properties of this locus.

  7. The molecular and clinical features of a family with a novel 3-base insertion, c.914_915insTGT (p.Val305_Asp306insVal) in exon 9 of PRPF31 are described to illustrate the salient clinical features of mutations in this gene.

  8. In asymptomatic carriers CNOT3 (show CNOT3 Antibodies) is expressed at low levels, allowing higher amounts of wild-type PRPF31 transcripts to be produced and preventing manifestation of retinal degeneration.

  9. Novel PRPF31 mutations associated with Chinese autosomal dominant retinitis pigmentosa patients occur at a relatively high frequency.

  10. The present study describes mapping of a locus for non-syndromic adRP (show PLIN2 Antibodies) at 19q13.42 (RP11 locus) in a family of Indian origin and identifies a novel deletion, c.59_65del7, in PRPF31 within the mapped interval.

Mouse (Murine) PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. The mouse retinal pigment epithelium (RPE (show RPE Antibodies))is the primary cell affected by mutations in the RNA splicing factors (PRPF3 (show PRPF3 Antibodies), PRPF8 (show PRPF8 Antibodies), and PRPF31), and these changes occur at an early age.

  2. found that PRP31 and PRPC8 (show PRPF8 Antibodies) as well as snRNAs are highly expressed in retinal cells

  3. CTNNBL1 (show CTNNBL1 Antibodies) is a novel nuclear localization sequence-binding protein (show NSR1 Antibodies) that recognizes RNA-splicing factors CDC5L (show CDC5L Antibodies) and Prp31

  4. The finding of similar degenerative changes in RPE (show RPE Antibodies) cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor (show SLU7 Antibodies) forms of retinitis pigmentosa.

  5. Our results demonstrate that mutations in PRPF31 gene affect rhodopsin (show RHO Antibodies) (RHO) pre-mRNA splicing and reveal a link between PRPF31 and RHO, two major genes in autosomal dominant retinitis pigmentosa.

  6. Our results indicate that PRPF31 mutations lead to defective pre-mRNA splicing of photoreceptor-specific genes and that the ubiquitously expressed adRP (show PLIN2 Antibodies) gene, PRPF31, is critical for pre-mRNA splicing of a subset of photoreceptor genes.

  7. The results imply that Prpf31 is necessary for survival, and there is no compensation mechanism in mouse for the lack of this splicing factor (show SLU7 Antibodies)

PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Antigen Profile

Protein Summary

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Gene names and symbols associated with PRPF31

  • PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) (PRPF31) antibody
  • pre-mRNA processing factor 31 (prpf31) antibody
  • PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) (PrpF31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (PRPF31) antibody
  • pre-mRNA processing factor 31 (PRPF31) antibody
  • pre-mRNA processing factor 31 (Prpf31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (Prpf31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (prpf31) antibody
  • 1500019O16Rik antibody
  • 2810404O06Rik antibody
  • AW554706 antibody
  • DDBDRAFT_0219465 antibody
  • DDBDRAFT_0304959 antibody
  • DDB_0219465 antibody
  • DDB_0304959 antibody
  • NY-BR-99 antibody
  • prp31 antibody
  • PRPF31 antibody
  • rp11 antibody
  • SNRNP61 antibody
  • zgc:66177 antibody

Protein level used designations for PRPF31

pre-mRNA processing factor 31 homolog , PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) , PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) , PRP31 pre-mRNA processing factor 31 homolog , u4/U6 small nuclear ribonucleoprotein Prp31-like , U4/U6 small nuclear ribonucleoprotein Prp31 , U4/U6 snRNP 61 kDa protein , hPrp31 , pre-mRNA-processing factor 31 , protein 61K , serologically defined breast cancer antigen NY-BR-99 , pre-mRNA processing factor 31-like protein

GENE ID SPECIES
456278 Pan troglodytes
8627218 Dictyostelium discoideum AX4
9832603 Ostreococcus tauri
100019854 Monodelphis domestica
100049878 Equus caballus
100137336 Papio anubis
100455616 Pongo abelii
26121 Homo sapiens
292536 Rattus norvegicus
495301 Xenopus laevis
476389 Canis lupus familiaris
513577 Bos taurus
68988 Mus musculus
393476 Danio rerio
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