You are viewing an incomplete version of our website. Please click to reload the website as full version.

PTK6 Protein tyrosine Kinase 6 (PTK6) ELISA Kits

The protein encoded by PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Additionally we are shipping PTK6 Antibodies (136) and PTK6 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PTK6 5753 Q13882
Anti-Rat PTK6 PTK6 366275  
PTK6 20459 Q64434
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top PTK6 ELISA Kits at antibodies-online.com

Showing 2 out of 9 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 15.6 pg/ml 62.5-4000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Human
96 Tests Log in to see 2 to 3 Days
$380.00
Details

More ELISA Kits for PTK6 Interaction Partners

Human PTK6 Protein tyrosine Kinase 6 (PTK6) interaction partners

  1. PELP1 (show PELP1 ELISA Kits) interacted with GR to activate Brk expression.

  2. PTK6 prolongs S-phase and increases the ability of gemcitabine to cause DNA damage in vitro and in vivo

  3. BRK expression in a majority of CC can interact with RTK, augmenting growth and interfering with proliferation inhibitors (SAM68 (show KHDRBS1 ELISA Kits)). Therapeutically targeting BRK function (in addition to RTK) should be of benefit for CC treatment.

  4. Additive impact of HER2 (show ERBB2 ELISA Kits)-/PTK6-RNAi on interactions with HER3 (show ERBB3 ELISA Kits) or IGF-1R (show IGF1R ELISA Kits) leads to reduced breast cancer progression

  5. overexpression or knockdown of PTK6 or ERK1/2 effectively removed the inhibition of S1P-induced migration by miR-17.

  6. Establishment of cross talk between PTK6 and CagA (show S100A8 ELISA Kits) by functional studies may further elucidate the underlying biology of H. pylori-mediated gastric cancer

  7. PTK6 is expressed in the normal human mammary gland, but does not appear to be active and may have kinase-independent functions that are distinct from its cancer promoting activities at the membrane.

  8. Down-regulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma.

  9. PTP1B (show PTPN1 ELISA Kits) inhibited BRK by dephosphorylating Tyr (show TYR ELISA Kits)-342, but activated SRC (show SRC ELISA Kits) by antagonizing PAG (show PRDX1 ELISA Kits)-dependent inhibition by CSK (show CSK ELISA Kits).

  10. Activating mutations in BRK in breast cancer may disrupt intramolecular interactions that normally maintain BRK in an autoinhibited conformation.

Mouse (Murine) PTK6 Protein tyrosine Kinase 6 (PTK6) interaction partners

  1. PTK6 prolongs S-phase and increases the ability of gemcitabine to cause DNA damage in vitro and in vivo

  2. Ptk6 promotes ERBB2 (show ERBB2 ELISA Kits)-induced mammary gland tumorigenesis in the mouse.

  3. Protein tyrosine kinase 6 has a role in mediating TNFalpha (show TNF ELISA Kits)-induced endothelial barrier dysfunction

  4. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT (show AKT1 ELISA Kits).

  5. expression of Brk/PTK6 in non-transformed mammary epithelial cells mediates p38 MAPK (show MAPK14 ELISA Kits) phosphorylation and promotes increased cellular survival, delayed involution, and latent tumor formation.

  6. a novel function for PTK6 at the plasma membrane

  7. PTK6 promotes STAT3 (show STAT3 ELISA Kits) activation in the colon following injection of the carcinogen azoxymethane and regulates STAT3 (show STAT3 ELISA Kits) activity in mouse colon tumors.

  8. AKT (show AKT1 ELISA Kits) is a direct substrate of PTK6 and AKT (show AKT1 ELISA Kits) tyrosine residues 315 and 326 are phosphorylated by PTK6.

  9. PTK6 associates with nuclear and cytoplasmic beta-catenin (show CTNNB1 ELISA Kits) and inhibits beta-catenin (show CTNNB1 ELISA Kits)- and T-cell factor (TCF (show HNF4A ELISA Kits))-mediated transcription.

  10. The tyrosine kinases Brk/PTK6/Sik, Srm (show SRM ELISA Kits), Frk/Rak/Gtk (show FRK ELISA Kits)/Iyk/Bsk (show EPHA5 ELISA Kits), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk family, is highly conserved and distinct.

PTK6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PTK6

  • PTK6 protein tyrosine kinase 6 (PTK6) antibody
  • protein tyrosine kinase 6 (PTK6) antibody
  • protein tyrosine kinase 6 (Ptk6) antibody
  • PTK6 protein tyrosine kinase 6 (Ptk6) antibody
  • BRK antibody
  • Sik antibody
  • tks antibody
  • Tksk antibody

Protein level used designations for PTK6

PTK6 protein tyrosine kinase 6 , protein-tyrosine kinase 6-like , breast tumor kinase , protein-tyrosine kinase 6 , protein-tyrosine kinase BRK , tyrosine-protein kinase BRK , protein tyrosine kinase 6 , src-related intestinal kinase , tyrosine kinase identified from skin

GENE ID SPECIES
100060532 Equus caballus
100438236 Pongo abelii
100589028 Nomascus leucogenys
5753 Homo sapiens
366275 Rattus norvegicus
20459 Mus musculus
529814 Bos taurus
Selected quality suppliers for PTK6 (PTK6) ELISA Kits
Did you look for something else?