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PXK Proteins (PXK)

PXK binds to the Na,K-ATPase beta-1 (ATP1B1\; MIM 182330) and beta-3 (ATP1B3\; MIM 601867) subunits and modulates both Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005 [PubMed 16135750]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PXK Antibodies (52) and PXK Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PXK 54899 Q7Z7A4
PXK 306203 Q4FZZ1
PXK 218699 Q8BX57
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Top PXK Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,666.67
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PXK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for PXK Interaction Partners

Human PXK interaction partners

  1. Two of these kinases that were classified as resistors were PX domain-containing serine/threonine kinase (PXK) and AP2-associated kinase 1 (AAK1), which promote receptor endocytosis and may enable cells to resist TRAIL-induced apoptosis

  2. genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L (show KIAA0319L Proteins) [rs2275247(A/G)] or JAZF1 (show JAZF1 Proteins) [rs1635852(C/T)] are not associated.

  3. Results confirm the genetic association of the locus 3p14.3 with systemic lupus erythematosus in Europeans and point to the ABHD6 (show ABHD6 Proteins) and not PXK, as the major susceptibility gene in the region.

  4. study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (show JAZF1 Proteins) (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis

  5. The rs6445975 polymorphism of PXK and the rs2304256 polymorphism of tyrosine kinase 2 (show TYK2 Proteins) are associated with the development of systemic lupus erythematosus in Europeans

  6. The association of PXK rs6445975 with systemic lupus erythematosus that was previously observed in Caucasians was not replicated in Koreans or in Hong Kong Chinese.

  7. These results indicate that PXK plays a critical role in epidermal growth factor receptor (show EGFR Proteins) trafficking through modulating ligand-induced ubiquitination of the receptor.

  8. MONaKA modulates brain Na,K-ATPase (show ATP1A1 Proteins) by binding tightly to its beta1 and beta3 subunits, and may thereby participate in the regulation of electrical excitability and synaptic transmission [MONaKA]

  9. study presents four new regions having genetic associations with systemic lupus erythematosus in women of European descent: ITGAM (show ITGAM Proteins), KIAA1542, PXK and rs10798269

Mouse (Murine) PXK interaction partners

  1. MONaKA modulates brain Na,K-ATPase (show ATP1A1 Proteins) by binding tightly to its beta1 and beta3 subunits, and may thereby participate in the regulation of electrical excitability and synaptic transmission.

PXK Protein Profile

Protein Summary

PXK binds to the Na,K-ATPase beta-1 (ATP1B1\; MIM 182330) and beta-3 (ATP1B3\; MIM 601867) subunits and modulates both Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005

Gene names and symbols associated with PXK Proteins (PXK)

  • PX domain containing serine/threonine kinase (PXK)
  • PX domain containing serine/threonine kinase (Pxk)
  • C230080L11Rik protein
  • D14Ertd813e protein
  • MONaKA protein

Protein level used designations for PXK Proteins (PXK)

PX domain-containing protein kinase-like protein , PX ser/thr kinase v2 , PX serine/threonine kinase , modulator of Na,K-ATPase long form , MONaKA , modulator of Na,K-ATPase

GENE ID SPECIES
54899 Homo sapiens
306203 Rattus norvegicus
218699 Mus musculus
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