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PYCARD Proteins

(PYD and CARD Domain Containing (PYCARD))
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PYCARD Protein (AA 1-149) (GST tag) PYCARD Protein (AA 1-149) (GST tag) PYCARD Protein (AA 1-149) (GST tag) (ABIN1316968)

PYCARD Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

PYCARD Protein (AA 1-195) (His tag) PYCARD Protein (AA 1-195) (His tag) PYCARD Protein (AA 1-195) (His tag) (ABIN3089316)

Crystallography grade PYCARD Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

PYCARD Protein (AA 1-193) (His tag) PYCARD Protein (AA 1-193) (His tag) PYCARD Protein (AA 1-193) (His tag) (ABIN3137154)

Crystallography grade PYCARD Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

PYCARD Proteins by Grade

Find PYCARD Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PYCARD Proteins by Origin

Find PYCARD Proteins for a variety of species such as anti-Human PYCARD, anti-Cow PYCARD, anti-Mouse PYCARD. The species listed below are among those available. Click on a link to go to the corresponding products.

PYCARD Proteins by Source

Here you will find PYCARD Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PYCARD Proteins by Protein Type

Here you can find PYCARD Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PYCARD Proteins by Application

Find PYCARD Proteins validated for a specific application such as ELISA, AbP, STD, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PYCARD Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316968
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3089316
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3137154
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730218
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713166
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713165
Quantity 20 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1636486
Quantity 1 mg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1646663
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PYCARD Proteins

Shi, Wang, Li, Zhan, Tang, Fina, Su, Pratt, Bu, Hildebrand, Lyon, Scott, Quan, Sun, Russell, Arnett, Jurek, Chen, Kravchenko, Mathison, Moresco, Monson, Ulevitch, Beutler: "NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component." in: Nature immunology, Vol. 17, Issue 3, pp. 250-8, (2016) (PubMed).

Aliases for PYCARD Proteins

PYD and CARD domain containing (PYCARD) Proteins
PYD and CARD domain containing (Pycard) Proteins
PYD and CARD domain containing (pycard) Proteins
9130417A21Rik Proteins
ASC Proteins
Asc Proteins
asc1 Proteins
CARD5 Proteins
masc Proteins
TMS Proteins
TMS-1 Proteins
TMS1 Proteins
TNS1 Proteins
zAsc Proteins
zgc:109874 Proteins
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