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PAX7 is a member of the paired box (PAX) family of transcription factors. Additionally we are shipping PAX7 Proteins (4) and PAX7 Kits (3) and many more products for this protein.
Showing 10 out of 133 products:
Human Polyclonal PAX7 Primary Antibody for EIA, WB - ABIN954012
Williamson, Missiaglia, de Reyniès, Pierron, Thuille, Palenzuela, Thway, Orbach, Laé, Fréneaux, Pritchard-Jones, Oberlin, Shipley, Delattre: Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010
Show all 5 references for ABIN954012
Human Polyclonal PAX7 Primary Antibody for WB - ABIN610569
Ku, Meier: Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells. in The Journal of biological chemistry 2000
Show all 3 references for ABIN610569
Human Polyclonal PAX7 Primary Antibody for EIA, IHC (p) - ABIN954013
Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010
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Human Polyclonal PAX7 Primary Antibody for IF, WB - ABIN2777185
Ezin, Sechrist, Zah, Bronner, Fraser: Early regulative ability of the neuroepithelium to form cardiac neural crest. in Developmental biology 2011
Show all 2 references for ABIN2777185
Human Polyclonal PAX7 Primary Antibody for IF (p), IHC (p) - ABIN739905
Oh, Lee, Lee, Oh, Lim, Ahn, Hwang, Kang: Functional and histological evidence for the targeted therapy using biocompatible polycaprolactone beads and autologous myoblasts in a dog model of fecal incontinence. in Diseases of the colon and rectum 2015
Chicken Polyclonal PAX7 Primary Antibody for IHC, WB - ABIN2779615
Du, Lawrence, Strzelecki, Rajput, Xia, Gottesman, Barr: Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma. in International journal of cancer. Journal international du cancer 2005
Cow (Bovine) Polyclonal PAX7 Primary Antibody for WB - ABIN2779614
Möller, Isaksson, Mandahl, Mertens, Panagopoulos: Comparison of the proximal promoter regions of the PAX3 and PAX7 genes. in Cancer genetics and cytogenetics 2007
Porcine skeletal muscle-derived PW1(pos)/Pax7(neg) interstitial cells are a source of stem/progenitor cells.
The total expression profile of MyoD (show MYOD1 Antibodies) and Pax7 genes suggests that higher muscularity in Pietrain pigs is associated with the presence of a greater number of active satellite stem cells compared to other breeds.
Pax7 might be one of the molecules involved in controlling the proliferation/differentiation ratio in the pool of satellite cells present in post-natal porcine skeletal muscles.
These data suggested that expression of the myogenic regulatory transcription factors are dependent upon expression of glypican-1 (show GPC1 Antibodies) and syndecan-4 (show SDC4 Antibodies) during satellite cell proliferation and differentiation, and Pax7 expression is influenced by glypican-1 (show GPC1 Antibodies).
these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD (show MYOD1 Antibodies)-dependent activation of miR (show MLXIP Antibodies)-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression
RAGE (show AGER Antibodies) upregulates myogenin (show MYOG Antibodies) which upregulates MyoD (show MYOD1 Antibodies) and downregulates PAX7, with consequent inhibition of proliferation and stimulation of differentiation.
Pax7 responds to NF-kappaB (show NFKB1 Antibodies) by impairing the regenerative capacity of myogenic cells in the muscle microenvironment to drive muscle wasting in cancer.
High prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas is associated with PAX7 loss.
Our study replicated previous GWAS findings for markers in VAX1 (show VAX1 Antibodies) in the Asian population, and identified rare variants in PAX7 and VAX1 (show VAX1 Antibodies) that may contribute to the etiology of CL(P)
In addition, eight genes classified as 'second tier' hits in the original study (PAX7, THADA, COL8A1 (show COL8A1 Antibodies)/FILIP1L (show FILIP1L Antibodies), DCAF4L2, GADD45G (show GADD45G Antibodies), NTN1 (show NTN1 Antibodies), RBFOX3 (show RBFOX3 Antibodies) and FOXE1 (show FOXE1 Antibodies)) showed evidence of linkage and association in this replication sample.
SUMOylation of Pax7 is essential for neural crest development in chick embryos and for the inhibitory roles of Pax7 in C2C12-muscle differentiation.
PAX3 (show PAX3 Antibodies)/7-FKHR (show FOXO1 Antibodies) gene fusions expression was detected in 56% of ARMS tumor samples.
Detection of PAX3 (show PAX3 Antibodies)/PAX7-FKHR (show FOXO1 Antibodies) fusion transcripts is a novel tool for Rhabdomyosarcoma diagnosis
PAX7-FKHR (show FOXO1 Antibodies) fusion gene inhibits myogenic differentiation via NF-kappaB (show NFKB1 Antibodies) upregulation.
Our results show that the expression of Pax6 (show PAX6 Antibodies) and Pax7 is widely maintained in the adult brain of Xenopus
The Pax3 (show PAX3 Antibodies) and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.
Results show that inhibition of pax7 does not prevent differentiation of satellite cells to myofibres, but it does prevent their maintenance as a stem cell population.
four novel polymorphisms were identified in the Pax7 gene; the association analysis of genotypes in the single and combined SNP(s) revealed consistent effects on growth traits in NY cattle
These results underscore DNA demethylation as a key mechanism driving myogenesis and identify specific Pax7-mediated DNA demethylation signatures to acquire and maintain the muscle-cell identity.
we propose that Nedd4 functions as a novel Pax7 regulator, which activity is temporally and spatially controlled to modulate the Pax7 protein levels and therefore satellite cell fate.
miR (show MLXIP Antibodies)-431 transgenic mice are a unique genetic model for investigating the cellular features and biological functions of Pax7(Lo) satellite cells during muscle development and regeneration.
Caspase 3 (show CASP3 Antibodies) cleavage of Pax7 has a role in inhibiting self-renewal of satellite cells
Brg1 (show SMARCA4 Antibodies) functions as a positive regulator for cellular proliferation and survival of primary myoblasts via pax7.
Loss of Pax7 expression is associated with craniofacial abnormalities.
Low RAGE (show AGER Antibodies) activity in embryonal rhabdomyosarcoma cells results in high PAX7 levels that sustain migration and invasiveness.
PAX7+ subset of A(single) spermatogonia functions as robust testis stem cells that maintain fertility in normal spermatogenesis in healthy mice and mediate recovery after severe germline injury, such as occurs after cancer therapy.
antagonism between Barx2 (show BARX2 Antibodies) and Pax7 in regulation of Wnt (show WNT2 Antibodies) signaling may help mediate the switch from myoblast proliferation to differentiation.
Nrf2 (show NFE2L2 Antibodies) deficiency promotes apoptosis and impairs PAX7/MyoD (show MYOD1 Antibodies) expression in aging skeletal muscle cells.
Pax7 identifies neural crest, chromatophore lineages and pigment stem cells during development.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
paired box 7
, paired box gene 7
, transcription factor pax-7
, PAX7 transcriptional factor
, paired box homeotic gene 7
, paired box protein Pax-7
, paired domain gene 7
, myogenic specification paired-box transcription factor Pax7
, paired box transcription factor PAX7
, paired box homeotic gene 7a
, paired box homeotic gene 7c
, paired box homeotic gene 7d
, paired box homeotic gene 7e