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anti-Paired Box 8 (PAX8) Antibodies

PAX8 encodes a member of the paired box (PAX) family of transcription factors. Additionally we are shipping PAX8 Proteins (15) and PAX8 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAX8 7849 Q06710
PAX8 81819 P51974
PAX8 18510 Q00288
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Top anti-PAX8 Antibodies at antibodies-online.com

Showing 10 out of 145 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-PAX8 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-PAX8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PAX8 Antibody (Center) in HL-60 cell line lysates (35ug/lane). PAX8 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184783 (3µg/ml) staining of paraffin embedded Human Thyroid Gland. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA, WB ABIN190912 (0.5µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using PAX8 mouse mAb against Hela (1) ,HEK293 (2) and Raji (3) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PAX8 Antibody (Center) (ABIN390860) in HL-60 cell line lysates (35 µg/lane). PAX8 (arrow) was detected using the purified polyclonal antibody. (LEFT)Formalin-fixed and paraffin-embedded mouse kidney reacted with PAX8 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RIGHT)Flow cytometric analysis of 293 cells using PAX8 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details

PAX8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-PAX8 Antibodies

  1. Human Polyclonal PAX8 Primary Antibody for IHC, ELISA - ABIN184783 : Pasca di Magliano, Di Lauro, Zannini: Pax8 has a key role in thyroid cell differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 3 references for ABIN184783

  2. Dog (Canine) Polyclonal PAX8 Primary Antibody for WB - ABIN2783221 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2783221

  3. Human Polyclonal PAX8 Primary Antibody for IHC (p), WB - ABIN374237 : Borgogni, Sarchielli, Sottili, Santarlasci, Cosmi, Gelmini, Lombardi, Cantini, Perigli, Luconi, Vannelli, Annunziato, Adorini, Serio, Crescioli: Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells. in Endocrinology 2008 (PubMed)
    Show all 2 references for ABIN374237

  4. Dog (Canine) Polyclonal PAX8 Primary Antibody for IHC, WB - ABIN2775952 : Nonaka, Tang, Chiriboga, Rivera, Ghossein: Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008 (PubMed)

  5. Human Monoclonal PAX8 Primary Antibody for ELISA, WB - ABIN969343 : McKnight, Cohen, Siddiqui: Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma. in Cancer cytopathology 2010 (PubMed)

  6. Human Polyclonal PAX8 Primary Antibody for ELISA, WB - ABIN190912 : Castro, Rebocho, Soares, Magalhães, Roque, Trovisco, Vieira de Castro, Cardoso-de-Oliveira, Fonseca, Soares, Sobrinho-Simões: PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma. in The Journal of clinical endocrinology and metabolism 2006 (PubMed)

  7. Human Polyclonal PAX8 Primary Antibody for EIA, WB - ABIN453254 : Ramos, Nesi-França, Boldarine, Pereira, Chiamolera, Camacho, Graf, de Lacerda, Carvalho, Maciel: Clinical and molecular analysis of thyroid hypoplasia: a population-based approach in southern Brazil. in Thyroid : official journal of the American Thyroid Association 2009 (PubMed)

More Antibodies against PAX8 Interaction Partners

Human Paired Box 8 (PAX8) interaction partners

  1. a substantial minority of solitary fibrous tumors express nuclear PAX8 and PAX2 (show PAX2 Antibodies)

  2. PAX8 staining is useful for distinguishing between primary thyroid squamous cell carcinoma and invasion or metastasis from extrathyroidal squamous cell carcinoma.

  3. PAX8 is expressed in the majority of benign, premalignant, and malignant endocervical glandular lesions.

  4. PAX8 mutation rate among congenital hypothyroidism patients

  5. the novel interplay between PAX8 and Neuropilin-2 (show NRP2 Antibodies)

  6. Heterozygous transition in exon 3 of PAX8 gene is associated with hyroid hypoplasia.

  7. miR (show MLXIP Antibodies)-146b-3p binds to the 3'-untranslated region of PAX8 and sodium/iodide symporter (show SLC5A5 Antibodies). miR (show MLXIP Antibodies)-146b and PAX8 regulate each other and share common target genes.

  8. we examined PAX8-PPARgamma (show PPARG Antibodies) rearrangement in 24 follicular thyroid carcinoma samples from Japanese patients. The fusion gene was detected in only one of 24 follicular thyroid carcinomas (4%).

  9. PAX8 protein expression was associated with germinal layers in forebrain and hindbrain development...and PAX8 expression is linked to better prognosis in medulloblastomas

  10. PAX2 (show PAX2 Antibodies) and PAX8 are useful biomarker in the differential diagnosis of ovarian serous and mucinous tumors

Xenopus laevis Paired Box 8 (PAX8) interaction partners

  1. Pax8 is required for cell proliferation of pronephric precursors and regulates the expression of hnf1b (show HNF1B Antibodies) and wnt (show WNT2 Antibodies) pathway genes in the kidney field.

  2. nephrogenic transcription factors (osr1 (show OSR1 Antibodies), osr2, hnf1b (show HNF1B Antibodies), lhx1 (show LHX1 Antibodies), pax8)play important role in nephrogenesis but have no pronephros induction potential upon overexpression; they activate transcription cascades reflecting activation by activin A (show INHBA Antibodies), retinoic acid

Mouse (Murine) Paired Box 8 (PAX8) interaction partners

  1. Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure

  2. PAX8 protein expression was associated with germinal layers in human and murine forebrain and hindbrain development.

  3. Pax8 is essential for function and survival of adult thyroid cells.

  4. a core regulatory subcircuit composed of Pax2 (show PAX2 Antibodies)/8, Gata3 (show GATA3 Antibodies) and Lim1 (show LHX1 Antibodies) turns on a deeper layer of transcriptional regulators while activating effector genes responsible for cell signaling and tissue organization.

  5. The Pax8 promoter appears to be autoregulated, a feature that might be responsible for the haploinsufficiency displayed by this gene.

  6. Inducible, Pax8-rtTA-based deletion of VHL (show VHL Antibodies) leads to organ-specific expression of epithelial HIF and erythropoietin (show EPO Antibodies) in liver and kidney without causing pathological changes.

  7. study concludes that Cadherin-16 is a novel downstream target of the transcription factor Pax8, likely since the early steps of thyroid development, and that its expression is associated with the fully differentiated state of the thyroid cell

  8. a thyroid-specific regulatory element in the 5' upstream region of the Pax8 gene

  9. these data identify Pax2 (show PAX2 Antibodies) and Pax8 as critical regulators that specify the nephric lineage.

  10. The Box protein Pax-8 gene is an important and cardiac-specific ALK3 downstream gene in the BMP signaling pathway during inter-ventricular septum development.

Zebrafish Paired Box 8 (PAX8) interaction partners

  1. Pax2a and Pax8 regulate cell differentiation during sensory placode formation

  2. pax8 works with related genes pax2a/pax2b to downregulate otic expression of foxi1 (show FOXI1 Antibodies), a necessary step for further otic development

  3. evolutionary links between jaw and ear formation can be traced to Fgf-Foxi1 (show FOXI1 Antibodies)-Pax8 pathways

  4. Pax2a and Pax8 are the main effectors downstream of Fgf signals in ear formation

  5. pax8 is initially required for normal otic induction, and subsequently pax8, pax2a and pax2b act redundantly to maintain otic fate

PAX8 Antigen Profile

Protein Summary

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with anti-Paired Box 8 (PAX8) Antibodies

  • paired box 8 (PAX8) antibody
  • paired box 8 (pax8) antibody
  • paired box 8 (Pax8) antibody
  • paired box gene 8 (Pax8) antibody
  • paired box gene 8 (pax8) antibody
  • Pax-8 antibody
  • PAX8 antibody
  • XPax-8 antibody
  • XPax8 antibody

Protein level used designations for anti-Paired Box 8 (PAX8) Antibodies

paired box 8 , paired box gene 8 , paired box protein Pax-8 , paired domain gene 8 , Pax-8 protein , Pax-8 DNA-binding transcription factor , XPax-8

GENE ID SPECIES
701906 Macaca mulatta
780226 Xenopus (Silurana) tropicalis
100189903 Pongo abelii
7849 Homo sapiens
81819 Rattus norvegicus
403927 Canis lupus familiaris
534661 Bos taurus
398132 Xenopus laevis
18510 Mus musculus
60637 Danio rerio
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