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Paired Box Gene 8 (PAX8) ELISA Kits

PAX8 encodes a member of a family of transcription factors that contain a characteristic N-terminal paired DNA-binding domain.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PAX8 PAX8 18510 Q00288
Anti-Rat PAX8 PAX8 81819 P51974
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More ELISA Kits for PAX8 Interaction Partners

Mouse (Murine) Paired Box Gene 8 (PAX8) interaction partners

  1. Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure

  2. PAX8 protein expression was associated with germinal layers in human and murine forebrain and hindbrain development.

  3. Pax8 is essential for function and survival of adult thyroid cells.

  4. a core regulatory subcircuit composed of Pax2 (show PAX2 ELISA Kits)/8, Gata3 (show GATA3 ELISA Kits) and Lim1 (show LHX1 ELISA Kits) turns on a deeper layer of transcriptional regulators while activating effector genes responsible for cell signaling and tissue organization.

  5. The Pax8 promoter appears to be autoregulated, a feature that might be responsible for the haploinsufficiency displayed by this gene.

  6. Inducible, Pax8-rtTA-based deletion of VHL (show VHL ELISA Kits) leads to organ-specific expression of epithelial HIF and erythropoietin (show EPO ELISA Kits) in liver and kidney without causing pathological changes.

  7. study concludes that Cadherin-16 is a novel downstream target of the transcription factor Pax8, likely since the early steps of thyroid development, and that its expression is associated with the fully differentiated state of the thyroid cell

  8. a thyroid-specific regulatory element in the 5' upstream region of the Pax8 gene

  9. these data identify Pax2 (show PAX2 ELISA Kits) and Pax8 as critical regulators that specify the nephric lineage.

  10. The Box protein Pax-8 gene is an important and cardiac-specific ALK3 downstream gene in the BMP signaling pathway during inter-ventricular septum development.

PAX8 Antigen Profile

Antigen Summary

This gene encodes a member of a family of transcription factors that contain a characteristic N-terminal paired DNA-binding domain. The encoded protein is important for proper differentiation of the thyroid and the kidney. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene names and symbols associated with Paired Box Gene 8 (PAX8) ELISA Kits

  • paired box gene 8 (Pax8) antibody
  • paired box 8 (Pax8) antibody
  • Pax-8 antibody

Protein level used designations for Paired Box Gene 8 (PAX8) ELISA Kits

paired box protein Pax-8 , Pax-8 protein , paired box gene 8

GENE ID SPECIES
18510 Mus musculus
81819 Rattus norvegicus
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