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Paired Related Homeobox 1 Proteins (PRRX1)

The DNA-associated protein encoded by PRRX1 is a member of the paired family of homeobox proteins localized to the nucleus. Additionally we are shipping PRRX1 Antibodies (86) and PRRX1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRRX1 5396 P54821
PRRX1 18933 P63013
PRRX1 266813 P63014
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Top PRRX1 Proteins at

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

PRRX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Paired Related Homeobox 1 (PRRX1) Interaction Partners

Human Paired Related Homeobox 1 (PRRX1) interaction partners

  1. the switch from Prrx1b to Prrx1a governs EMT (show ITK Proteins) plasticity in both mouse models of PDAC and human PDAC

  2. These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells

  3. Our results indicate that activation of Notch (show NOTCH1 Proteins) signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion.

  4. We conclude that miR (show MLXIP Proteins)-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression.

  5. Overexpression of PRRX1 in stably overexpressed-miR (show MLXIP Proteins)-124 cell lines could rescue the effects of radiosensitivity enhancement brought by miR (show MLXIP Proteins)-124.

  6. In the rare variant joint analysis, damaging variants within the PRRX1 region showed significant association with AF.

  7. PRRX1 is an indicator of metastasis and poor prognosis in colorectal cancer cases.

  8. We show that the homeobox (show Lbx1 Proteins) factor Prrx1 is an EMT (show ITK Proteins) inducer conferring migratory and invasive properties. The loss of Prrx1 is required for cancer cells to metastasize in vivo, which revert to the epithelial phenotype concomitant with the acquisition of stem cell properties.

  9. Mutation analysis was performed after sequencing the entire coding regions of OTX2 (show OTX2 Proteins) and PRRX1 genes isolated from the proband and his parents. After thorough analysis, no DNA variations were detected.

  10. HOXA7 (show HOXA7 Proteins), PIXT1 and PRRX1 homeobox genes have different patterns of expression in oral squamous cell carcinomas depending on its histological features.

Mouse (Murine) Paired Related Homeobox 1 (PRRX1) interaction partners

  1. Induction of Prx1 (show PRDX1 Proteins) by hypoxia regulates heme oxygenase-1 (show HMOX1 Proteins) via NF-kappaB (show NFKB1 Proteins) in oral cancer.

  2. PRX-1 has a regulatory role in NF-kappaB (show NFKB1 Proteins) nuclear translocation.

  3. The data of this study suggested that Prx1 (show PRDX1 Proteins) plays an important role as a key switch for neural cell lineage determination and the maintenance of the self-renewal of adult NSCs at several stages in the adult brain.

  4. These observations suggest that increased Prrx1 expression may promote TGFbeta (show TGFB1 Proteins) activity in adipose tissue and thereby contribute to aberrant adipocyte function during obesity.

  5. The two isoforms, Prrx1a and Prrx1b, regulate migration and invasion, respectively, in pancreatic cancer cells

  6. The results suggested that scarless skin-wound healing may require activation of the prx1 (show PRDX1 Proteins) limb enhancer, and competence to activate the enhancer is probably a prerequisite for epimorphic regeneration, such as limb regeneration.

  7. These results identify the homeobox protein (show HOXA1 Proteins) Prx1 (show PRDX1 Proteins) as an obligate mediator of TNF (show TNF Proteins) inhibition of Osx (show SP7 Proteins) and differentiation of osteoblast progenitors.

  8. Generation of Ctgf (show CTGF Proteins)(+/LacZ (show GLB1 Proteins)) heterozygous null mice and tissue-specific null Ctgf (show CTGF Proteins) mice, where Ctgf (show CTGF Proteins) is flanked by lox (show LOX Proteins) sequences with mice expressing the Cre recombinase (show RAG1 Proteins) under the control of the paired-related homeobox gene 1 (Prx1 (show PRDX1 Proteins)) enhancer (Prx1 (show PRDX1 Proteins)-Cre).

  9. Data show that, during mandibular morphogenesis, Prx1 (show PRDX1 Proteins)/2 gene products play multiple roles including the cell survival, the region-specific terminal differentiation of Meckelian chondrocytes and osteogenesis.

  10. Results show that Prx (show PRX Proteins) I and II are constitutively expressed in the testis and their expression levels are decreased to some extent as the testis develops.

PRRX1 Protein Profile

Protein Summary

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.

Gene names and symbols associated with PRRX1

  • paired related homeobox 1a (prrx1a)
  • paired related homeobox 1 (PRRX1)
  • similar to PEPP subfamily gene 2 (PRRX1)
  • paired related homeobox 1 (Prrx1)
  • A230024N07Rik protein
  • AA755424 protein
  • AGOTC protein
  • AI385634 protein
  • AI843499 protein
  • cb329 protein
  • gMHox protein
  • homeobox protein
  • K-2 protein
  • mHox protein
  • PHOX1 protein
  • Pmx protein
  • Pmx1 protein
  • PRRX1 protein
  • Prx-1 protein
  • Prx1 protein
  • wu:fa09h05 protein
  • wu:fb52c01 protein
  • zgc:64055 protein

Protein level used designations for PRRX1

paired mesoderm homeo box 1 , paired related homeobox 1 , prx1 , paired mesoderm homeobox 1 , paired mesoderm homeobox protein 1 , similar to PEPP subfamily gene 2 , homeobox protein PHOX1 , paired mesoderm homeobox 1 isoform pmx-1b , paired-related homeobox protein 1 , homeobox protein K-2 , homeobox protein mHox , rHox , homeobox protein MHOX , paired-related homeotic gene product

406431 Danio rerio
540901 Bos taurus
609105 Canis lupus familiaris
702704 Macaca mulatta
736677 Pan troglodytes
695352 Macaca mulatta
5396 Homo sapiens
18933 Mus musculus
266813 Rattus norvegicus
373941 Gallus gallus
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