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Pancreatic Polypeptide Receptor 1 (PPYR1) ELISA Kits

high affinity receptor for pancreatic polypeptide that inhibits gall bladder contraction, gut motility, and pancreatic secretion.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PPYR1 PPYR1 5540 P50391
Anti-Mouse PPYR1 PPYR1 19065 Q61041
Anti-Rat PPYR1 PPYR1 29471 Q63447
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More ELISA Kits for Pancreatic Polypeptide Receptor 1 Interaction Partners

Rabbit Pancreatic Polypeptide Receptor 1 (PPYR1) interaction partners

  1. Results suggest that rabbit and human Y1, Y2 and Y5 receptor (show NPY5R ELISA Kits) subtypes are well conserved, whereas Y4 receptors are less well conserved.

Human Pancreatic Polypeptide Receptor 1 (PPYR1) interaction partners

  1. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (show GCG ELISA Kits) release through PPYR1 receptors expressed by alpha-cells.

  2. Pancreatic polypeptide (show PPY ELISA Kits) is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.

  3. structure determination of transmembrane segments of Y4 and the yeast Ste2p G-protein-coupled receptors

  4. Results report on the functional reconstitution of the hY(2)R and the hY(4 (show CRY1 ELISA Kits))R in Sf9 insect cells using the baculovirus system.

  5. The pharmacologic insensitivity of pancreatic polypeptide responses to either NPY1- or NPY2-receptor antagonism, or to tetrodotoxin, indicates that NPY4 receptors are involved and that they are predominantly post-junctional in colon mucosa.

  6. PP1 (show PPA1 ELISA Kits) is targeted to DNA polymerase (show POLB ELISA Kits) III via an interaction with the p68 (show ANXA6 ELISA Kits) subunit.

  7. Results suggest that rabbit and human Y1, Y2 and Y5 receptor (show NPY5R ELISA Kits) subtypes are well conserved, whereas Y4 receptors are less well conserved.

Mouse (Murine) Pancreatic Polypeptide Receptor 1 (PPYR1) interaction partners

  1. Genetic deletion of the Y4 receptor impaired fear extinction, an effect that was rescued by short-term fasting

  2. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (show GCG ELISA Kits) release through PPYR1 receptors expressed by alpha-cells.

  3. Data describe the complex interaction between Y2/Y4 receptors in control of bone mass, and suggest that the reduction in cortical bone observed in the absence of leptin (show LEP ELISA Kits) is due to the anti-osteogenic effect of elevated hypothalamic NPY (show NPY ELISA Kits) levels.

  4. Data from studies in knockout mice suggest that signaling through Y4 receptor prevents development of short-/long-term anxiety-/depression-like behaviour caused by acute immune challenge. Study includes comparison with Y2 receptor (show NPY2R ELISA Kits) knockout mice.

  5. Pancreatic polypeptide (show PPY ELISA Kits) enhances colonic contractile activity and fecal output through neuropeptide Y (show NPY ELISA Kits) Y(4) receptor, and a neuropeptide Y (show NPY ELISA Kits) Y(4) receptor agonist might offer a novel therapeutic approach to ameliorate constipation.

  6. These findings show that pancreatic polypeptide (show PPY ELISA Kits) reduces food intake predominantly via stimulation of the anorexigenic alpha-MSH signaling pathway, and that this effect is mediated by direct action on local Y4 receptors within the arcuate nucleus.

  7. These findings attest to a differential role of Y2 and Y4 receptor signalling in the circadian control of behaviours that balance energy intake and energy expenditure.

  8. Y1, Y2, and Y4 receptors are not crucially involved in NPY's hyperphagic, hypogonadal (show GNRH1 ELISA Kits), and obesogenic effects, but they are responsible for the central regulation of circulating insulin (show INS ELISA Kits) levels by NPY (show NPY ELISA Kits).

  9. The neuropeptide Y (NPY (show NPY ELISA Kits))-Y4 receptor knockout mice Increased novelty-induced motor activity and reduced depression-like behavior.

Pancreatic Polypeptide Receptor 1 (PPYR1) Antigen Profile

Antigen Summary

high affinity receptor for pancreatic polypeptide that inhibits gall bladder contraction, gut motility, and pancreatic secretion

Gene names and symbols associated with PPYR1

  • pancreatic polypeptide receptor 1 (PPYR1) antibody
  • neuropeptide Y receptor Y4 (npy4r) antibody
  • pancreatic polypeptide receptor 1 (LOC100230830) antibody
  • neuropeptide Y receptor Y4 (NPY4R) antibody
  • neuropeptide Y receptor Y4 (Npy4r) antibody
  • LOC100230830 antibody
  • NPY4-R antibody
  • NPY4R antibody
  • NYYR-D antibody
  • PP1 antibody
  • Ppyr1 antibody
  • Y4 antibody

Protein level used designations for PPYR1

gastric Y4 receptor , neuropeptide Y receptor Y4 , neuropeptide Y receptor type 4 , G-protein coupled receptor , neuropeptide Y receptor 4 , pancreatic polypeptide receptor 1 , neuropeptide Y receptor type 4-like , NPY4-R , NPYR-D , PP1 , Y4 receptor

GENE ID SPECIES
100008938 Oryctolagus cuniculus
428955 Gallus gallus
489082 Canis lupus familiaris
694492 Macaca mulatta
747423 Pan troglodytes
100127810 Xenopus (Silurana) tropicalis
100230830 Taeniopygia guttata
100431670 Pongo abelii
100590028 Nomascus leucogenys
5540 Homo sapiens
19065 Mus musculus
29471 Rattus norvegicus
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