Pannexin 2 Proteins (PANX2)

The protein encoded by PANX2 belongs to the innexin family. Additionally we are shipping Pannexin 2 Antibodies (88) and Pannexin 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PANX2 56666 Q96RD6
PANX2 406218 Q6IMP4
Rat PANX2 PANX2 362979 P60571
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Top Pannexin 2 Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

PANX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

More Proteins for Pannexin 2 (PANX2) Interaction Partners

Human Pannexin 2 (PANX2) interaction partners

  1. The results of this study do not support a major contribution of PANX1 (show PANX1 Proteins)-3 to disease risk of schizophrenia according to DSM-5.

  2. There is dense expression of Panx2 in the enteric nervous system. The substantial increase in Panx2 mRNA in ulcerative colitis (UC) muscle but not protein suggests that the Panx2 translation process may be disrupted in UC.

  3. Data suggest that both up-regulation and down-regulation of expression of pannexins (PANX1 (show PANX1 Proteins), PANX2, PANX3 (show PANX3 Proteins)) are associated with disease onset and/or progression; examples include neoplasms, multiple sclerosis, migraine, and hypertension. [REVIEW]

  4. Panx1 (show PANX1 Proteins) and Panx2 expression was detected in the temporal lobe cortex of patients with temporal lobe epilepsy and in the control tissues.

  5. Pannexin1 (show PANX1 Proteins) and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other

  6. These data do not suggest that Panx2 or Cx36 (show GJD2 Proteins) could increase the risk of schizophrenia in the Japanese population.

  7. According to brain cancer gene expression database REMBRANDT, PANX2 expression levels can predict post diagnosis survival for patients with glial tumors.

Mouse (Murine) Pannexin 2 (PANX2) interaction partners

  1. It used overlap-extension cloning to create the first chimeric Panx, consisting of Panx2 with the Panx1 (show PANX1 Proteins) C-terminus (Panx2(Panx1CT)), to determine whether the Panx1 (show PANX1 Proteins) C-terminus influences the trafficking of Panx2.

  2. ). Pannexin double-knockout mice (Px1 (show PANX1 Proteins)(-/-) Px2(-/-)) were less impaired in parameters such as exploration, anxiety, sensorimotor function and behavioral symmetry.

  3. In situ hybridization revealed that mRNAs for Panx1 (show PANX1 Proteins) and Panx2 were both expressed in the olfactory epithelium and olfactory bulb.

  4. Px1 (show PANX1 Proteins) and Px2 underlie channel function in neurons and contribute to ischemic brain damage

  5. Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment

  6. Panx2 strongly interacts with the core and high-mannose species of Panx1 (show PANX1 Proteins) but not with Panx3 (show PANX3 Proteins). The combination of Panx1 (show PANX1 Proteins) & Panx2 results in compromised channel function.

  7. Results reveal a widespread and similar mRNA distribution for both pannexin 1 (show PANX1 Proteins) and 2, but indicate that they are inversely regulated during the development of the rat brain.

  8. Panx1 (show PANX1 Proteins) and Panx2 are abundantly expressed in the retina, and may therefore contribute to the electrical and metabolic coupling, or to signaling between retinal neurons

  9. Data show that Panx2 is expressed in the spiral and Scarpa's ganglion neurons.

Pannexin 2 (PANX2) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Pannexin 2 Proteins (PANX2)

  • pannexin 2 (PANX2)
  • pannexin 2 (LOC100533356)
  • pannexin 2 (panx2)
  • pannexin 2 (Panx2)
  • hPANX2 protein
  • PANX2 protein
  • PX2 protein
  • si:ch211-192n14.2 protein

Protein level used designations for Pannexin 2 Proteins (PANX2)

pannexin 2 , pannexin-2 , pannexin-2-like

470248 Pan troglodytes
539070 Bos taurus
100519315 Sus scrofa
100533356 Aplysia californica
100579918 Nomascus leucogenys
557828 Danio rerio
426934 Gallus gallus
56666 Homo sapiens
481195 Canis lupus familiaris
406218 Mus musculus
362979 Rattus norvegicus
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