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Pantothenate Kinase 1 Proteins (PANK1)

PANK1 encodes a member of the pantothenate kinase family. Additionally we are shipping PANK1 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PANK1 53354 Q8TE04
PANK1 75735 Q8K4K6
Rat PANK1 PANK1 294088  
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Top PANK1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PANK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Pantothenate Kinase 1 (PANK1) Interaction Partners

Arabidopsis thaliana Pantothenate Kinase 1 (PANK1) interaction partners

  1. Arabidopsis has two functional type-II pantothenate kinases with overlapping activity. AtPANK1 is a monofunctional enzyme that has a single type-II antothenate kinase domain. [PANK1]

Human Pantothenate Kinase 1 (PANK1) interaction partners

  1. p53 (show TP53 Proteins) plays an important role in regulating energy homeostasis through transcriptional control of PANK1.

  2. PANK deficiency leads to abnormalities in F-actin organization.

  3. molecular cloning and characterization of a new human PanK gene

  4. PPARalpha transcription factor as a major factor governing hepatic CoA levels by specific modulation of PANK1alpha gene expression

  5. analysis of the homodimeric structures of the catalytic cores of PanK1alpha and PanK3 (show PANK3 Proteins) in complex with acetyl-CoA (show LPCAT2 Proteins) and the the structural effects of the PanK2 (show PANK2 Proteins) mutations that have been implicated in neurodegeneration

Mouse (Murine) Pantothenate Kinase 1 (PANK1) interaction partners

  1. Pank1 genetic deficiency can be corrected using phosphopantothenate diet replacement therapy.

  2. The results indicate that Pank1 deficiency drives a whole-body metabolic adaptation that improves aspects of the diabetic phenotype and uncouples hyperglycaemia and hyperinsulinaemia from obesity in leptin (show LEP Proteins)-deficient mice.

  3. p53 (show TP53 Proteins) plays an important role in regulating energy homeostasis through transcriptional control of PANK1.

  4. The data indicate that PanK1 and PanK2 can compensate for each other to supply tissue CoA.

  5. data illustrate the importance of PanK1 and elevated liver CoA levels during fasting to support the metabolic transition from glucose utilization and fatty acid synthesis to gluconeogenesis and fatty acid oxidation

PANK1 Protein Profile

Protein Summary

This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636).

Gene names and symbols associated with Pantothenate Kinase 1 Proteins (PANK1)

  • pantothenate kinase 1 (PANK1)
  • pantothenate kinase 1b (pank1b)
  • Pantothenate kinase 1 (PANK1)
  • pantothenate kinase 1 (EHI_183060)
  • pantothenate kinase 1 (Pank1)
  • 4632412I06Rik protein
  • 5430426F23Rik protein
  • ATCOAA protein
  • ATPANK1 protein
  • DKFZp469J1021 protein
  • im:7149302 protein
  • Pank protein
  • PANK1 protein
  • Pank1a protein
  • Pank1b protein
  • panK1beta protein
  • pantothenate kinase 1 protein
  • T13D8.31 protein
  • T13D8_31 protein
  • wu:fb51a11 protein
  • zgc:158746 protein

Protein level used designations for Pantothenate Kinase 1 Proteins (PANK1)

pantothenate kinase 1 , pantothenic acid kinase 1 , mPank , mPank1 , pantothenate kinase 1 beta

GENE ID SPECIES
423792 Gallus gallus
450590 Pan troglodytes
565059 Danio rerio
842339 Arabidopsis thaliana
6219408 Entamoeba histolytica HM-1:IMSS
100024817 Monodelphis domestica
100171452 Pongo abelii
53354 Homo sapiens
75735 Mus musculus
294088 Rattus norvegicus
486790 Canis lupus familiaris
100154650 Sus scrofa
535887 Bos taurus
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