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PRCC encodes a protein that may play a role in pre-mRNA splicing. Additionally we are shipping PRCC Antibodies (13) and PRCC Proteins (3) and many more products for this protein.
Our data suggest a scenario in which, during the course of renal cell carcinoma development, an initial PRCCTFE3-induced cell cycle delay must be numbed, thus permitting continued proliferation and progression towards full-blown malignancy.
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X\;1)(p11\;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
papillary renal cell carcinoma (translocation-associated)
, papillary renal cell carcinoma translocation-associated gene product
, proline-rich protein PRCC
, papillary renal cell carcinoma translocation-associated gene protein