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Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) Proteins (PARD6B)

PARD6B is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Additionally we are shipping Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PARD6B 58220 Q9JK83
Rat PARD6B PARD6B 362279  
PARD6B 84612 Q9BYG5
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Top Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PARD6B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

Top referenced Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) Proteins

  1. Human PARD6B Protein expressed in Escherichia coli (E. coli) - ABIN1098716 : Joberty, Petersen, Gao, Macara: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. in Nature cell biology 2000 (PubMed)
    Show all 2 references for ABIN1098716

  2. Human PARD6B Protein expressed in Wheat germ - ABIN1314003 : Krishnamurthy, Wang, Silva, Condie, Bieberich: Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis. in The Journal of biological chemistry 2007 (PubMed)

More Proteins for Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) (PARD6B) Interaction Partners

Mouse (Murine) Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) (PARD6B) interaction partners

  1. PAK4 (show PAK4 Proteins) phosphorylates Par6B at Ser143 blocking its interaction with Cdc42 (show CDC42 Proteins).

  2. Pard6b is necessary for blastocyst morphogenesis

Human Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) (PARD6B) interaction partners

  1. found that the polarity determinants Cdc42 (show CDC42 Proteins), Par6B, PKCzeta (show PRKCZ Proteins)/iota and the structural proteins ezrin (show EZR Proteins) and phospho-ezrin (show EZR Proteins) were lost from the apical membrane and accumulated either in the cytoplasm or on the basal side of enterocytes in patients

  2. PAK4 (show PAK4 Proteins) phosphorylates Par6B at Ser143 blocking its interaction with Cdc42 (show CDC42 Proteins).

  3. Data conclude that Par6B and aPKC control mitotic spindle orientation in polarized epithelia and, furthermore, that aPKC coordinately regulates multiple processes to promote morphogenesis.

  4. This study demonstrates that controlled regulation of PAK4 (show PAK4 Proteins) is required for apical junction formation in lung epithelial cells and highlights potential cross-talk between two Cdc42 (show CDC42 Proteins) targets, PAK4 (show PAK4 Proteins) and Par6B.

  5. The ability of SRC (show SRC Proteins) family coactivators to regulate the expression of one of these genes, PARD6B/Par6, was confirmed by using cells individually depleted of SRC-1 (show SRC Proteins).

  6. Interaction between PAR-3 (show F2RL2 Proteins) and the aPKC-PAR-6 (show PARD6A Proteins) complex is indispensable for apical domain development of epithelial cells.

Xenopus laevis Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) (PARD6B) interaction partners

  1. Data indicate that the polarity protein Partitioning defective-6 homolog beta (Par6b) regulates not only the dynamics of apicobasal polarity but also integrity of the developing stratified epidermis.

  2. ephrinB1 (show EFNB1 Proteins) associates with the Par (show AFG3L2 Proteins) polarity complex protein Par-6 (show PARD6A Proteins) and can compete with the small GTPase (show RACGAP1 Proteins) Cdc42 (show CDC42 Proteins) for association with Par-6.

Par-6 Partitioning Defective 6 Homolog beta (C. Elegans) (PARD6B) Protein Profile

Protein Summary

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

Gene names and symbols associated with PARD6B

  • par-6 partitioning defective 6 homolog beta (C. elegans) (PARD6B)
  • par-6 (partitioning defective 6) homolog beta (C. elegans) (Pard6b)
  • par-6 family cell polarity regulator beta (PARD6B)
  • par-6 partitioning defective 6 homolog beta (pard6b)
  • par-6 partitioning defective 6 homolog beta (C. elegans) (pard6b)
  • AV025615 protein
  • PAR-6 protein
  • PAR-6B protein
  • par6 protein
  • PAR6B protein
  • PARD6B protein
  • pard6beta protein
  • si:dkey-192i18.6 protein

Protein level used designations for PARD6B

par-6 partitioning defective 6 homolog beta (C. elegans) , PAR-6 beta , PAR-6B , partitioning defective 6 homolog beta , partitioning-defective protein 6, beta , par-6 partitioning defective 6 homolog beta , partitioning defective 6 beta

GENE ID SPECIES
100052187 Equus caballus
712004 Macaca mulatta
100022922 Monodelphis domestica
100597121 Nomascus leucogenys
58220 Mus musculus
362279 Rattus norvegicus
84612 Homo sapiens
398165 Xenopus laevis
100124652 Danio rerio
419352 Gallus gallus
485926 Canis lupus familiaris
539687 Bos taurus
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