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anti-Paraoxonase 1 (PON1) Antibodies

The enzyme encoded by PON1 is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Additionally we are shipping Paraoxonase 1 Kits (65) and Paraoxonase 1 Proteins (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PON1 5444 P27169
PON1 18979 P52430
PON1 84024 P55159
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Top anti-Paraoxonase 1 Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-PON1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µg/ml using anti-PON1 antibody (ARP41400_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of CEM cells using PON1 Antibody (Center) Cat.-No AP53390PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with PON1 Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of PON1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PON1 (arrow) using rabbit polyclonal PON1 Antibody (Center) (ABIN654641). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PON1 gene (Lane 2) . 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Goat Un-conjugated ELISA, WB EB09286 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details

PON1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Paraoxonase 1 Antibodies

  1. Human Polyclonal PON1 Primary Antibody for EIA, FACS - ABIN954245 : Cagirci, Cay, Karakurt, Durmaz, Yazihan, Canga, Aydin, Acikel, Kilic, Topaloglu, Aras, Demir, Akdemir: Paraoxonase activity might be predictive of the severity of aortic valve stenosis. in The Journal of heart valve disease 2010 (PubMed)
    Show all 3 references for ABIN954245

  2. Human Monoclonal PON1 Primary Antibody for FACS, IHC - ABIN1724909 : Saadat: Paraoxonase 1 genetic polymorphisms and susceptibility to breast cancer: a meta-analysis. in Cancer epidemiology 2012 (PubMed)
    Show all 2 references for ABIN1724909

  3. Human Monoclonal PON1 Primary Antibody for ICC, FACS - ABIN1724910 : Yesilova, Turan, Ucmak, Selek, Halil Yavuz, Tanr?kulu: Reduced serum paraoxonase-1 levels in vitiligo: further evidence of oxidative stress. in Redox report : communications in free radical research 2012 (PubMed)
    Show all 2 references for ABIN1724910

  4. Human Polyclonal PON1 Primary Antibody for ELISA, WB - ABIN562316 : Gupta, Kandimalla, Priyanka, Singh, Gill, Singh: Effect of Resveratrol and Nicotine on PON1 Gene Expression: In Vitro Study. in Indian journal of clinical biochemistry : IJCB 2014 (PubMed)

  5. Human Polyclonal PON1 Primary Antibody for FACS, IHC (p) - ABIN654641 : Guglielmetti, Mazza, Pagano, Carrella, Sciuto, Nodari, Pezzolato, Richelmi, Baioni, Caramelli, Acutis, Bozzetta: Identification by a proteomic approach of a plasma protein as a possible biomarker of illicit dexamethasone treatment in veal calves. in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2014 (PubMed)

  6. Chicken Polyclonal PON1 Primary Antibody for WB - ABIN2776789 : Rosenblat, Gaidukov, Khersonsky, Vaya, Oren, Tawfik, Aviram: The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux. in The Journal of biological chemistry 2006 (PubMed)

  7. Human Polyclonal PON1 Primary Antibody for IHC, WB - ABIN2776787 : Penco, Buscema, Patrosso, Marocchi, Grossi: New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. in BMC bioinformatics 2008 (PubMed)

  8. Human Polyclonal PON1 Primary Antibody for WB - ABIN375141 : Bhattacharyya, Nicholls, Topol, Zhang, Yang, Schmitt, Fu, Shao, Brennan, Ellis, Brennan, Allayee, Lusis, Hazen: Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. in JAMA 2008 (PubMed)

More Antibodies against Paraoxonase 1 Interaction Partners

Human Paraoxonase 1 (PON1) interaction partners

  1. genetic association study in population of women in Brazil: Data suggest an SNP in promoter of PON1 [T(-107)C, rs705379] is associated with variations in serum PON1 activity; PON1 is higher with CC genotype; high-fat diet down-regulates PON1 activity.

  2. No evidence that the Q192R and L55M polymorphisms of PON1 impacted on the probability of reaching extreme ages was found although this cannot be completely ruled out.

  3. The AA genotype of the rs854560 SNPs of the PON1 gene is associated with increased mortality in patients after myocardial infarction in the subpopulation of patients with lowered glomerular filtration rate.

  4. toxicogenetics/genetic association study in population in Turkey: Data suggest SNP in PON1 (192Q/R) is associated with susceptibility to organophosphate poisoning; plasma ACHE activities of exposed workers vary w/ PON1 genotype: 192RR>192QR>192QQ.

  5. PON-1 55 L/M and 192Q/R polymorphisms and allelic variants are not related with the risk for migraine in Turkish people.

  6. Data suggest that serum PON1 activity is up-regulated in subjects treated with cholesterol-lowering agents (fibrates with/without statins) in prevention of cardiovascular disease (CVD) in patients at risk for CVD. [META-ANALYSIS, REVIEW]

  7. Leu-9, Tyr (show TYR Antibodies)-185, and Tyr (show TYR Antibodies)-293 of PON1 are importance in binding to HDL (show HSD11B1 Antibodies) and catalytic activity.

  8. PON1 Q192R polymorphism is likely to be a risk factor for cataract development in Pakistani population while PON1 L55M was not found to be associated with cataract.

  9. presence of an association between the PON1 gene polymorphism and serum levels of advanced glycation end products and advanced oxidation protein products in farmers occupationally exposed to pesticides

  10. Molecular dynamics simulation studies were employed on selected recombinant h-PON1 (rh-PON1) mutants to understand the effect of amino acid substitutions at position 192 on the structural features of the active site of the enzyme.

Mouse (Murine) Paraoxonase 1 (PON1) interaction partners

  1. results suggest that Hyperhomocysteinemia plays an intricate role in dysfunctional HDL (show HSD11B1 Antibodies), owing to the lack of PON1. This contributes to vascular endothelial impairment and atherosclerosis.

  2. Maternal PON1 status modulates the effects of repeated gestational chlorpyrifos oxon exposure on fetal-brain gene expression and on inhibition of both maternal and fetal biomarker enzymes.

  3. 5,6-dihydroxyeicosatrienoate-1,5-lactone, a stable metabolite of arachidonic acid, is a potential substrate for PON1.

  4. HDL (show HSD11B1 Antibodies) (mostly HDL3), stimulates PON1 antiatherogenic activities in mouse macrophages.

  5. Findings suggest that Pon1 interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis

  6. The study demonstrated a significant decline in PON1 activity which correlates with increased LDL oxidation after 8 months of age in Wistar rats.

  7. PON1 plays a protective role against hepatic derangements, secondary to fat and cholesterol overnutrition. PON1 deficiency is associated with oxidative stress and metabolic alterations leading to liver steatosis.

  8. PON1 is not essential for normal development, function, ageing, and the defense against light damage of the mouse retina.

  9. Suggest that PON1 decreases sustained pro-inflammatory reactions, which subsequently can attenuate plaque progression.

  10. PON1 plays a beneficial role in glucose regulation and metabolism and may serve as an important tool in diabetes control.

Pig (Porcine) Paraoxonase 1 (PON1) interaction partners

  1. PON1 behaves as a negative acute phase protein (show ORM1 Antibodies) in pigs since a significant decrease (P<0.05) in its activity after 72 h of the induction of the inflammation was observed with all substrates.

Cow (Bovine) Paraoxonase 1 (PON1) interaction partners

  1. The results suggest that PON1 might be a better parameter for minimal redox state changes in serum, shortly after labour in the examined breeds.

  2. Data indicate that Cu(2+), Mn(2+), Zn(2+), Ni(2 (show VMP1 Antibodies)+), and Pb(2+) were found to inhibite the paraoxonase 1 (PON1) enzyme activity in a concentration-dependent fashion.

  3. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1, 2 and 3 in granulosa cells and PON1 activity in follicular fluid and plasma of dairy cows.

  4. Significantly lower PON1 activity and PON1/high density lipoprotein ratio in lactating cows compared to heifers showed that metabolic efforts during pregnancy, parturition and lactation influence PON1 activity due to oxidative stress.

  5. The activity of PON1 and malondialdehyde in late pregnancy and early lactation in dairy cattle is reported.

Rabbit Paraoxonase 1 (PON1) interaction partners

  1. ApoE (show APOE Antibodies) mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 Antibodies) paraoxonase activity

  2. PON1 can decrease the AChE inhibition, and alleviated clinical signs and tissue damage caused by dichlorvos.

Paraoxonase 1 (PON1) Antigen Profile

Protein Summary

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Gene names and symbols associated with anti-Paraoxonase 1 (PON1) Antibodies

  • paraoxonase 1 (pon1) antibody
  • paraoxonase 1 (PON1) antibody
  • paraoxonase 1 (Pon1) antibody
  • ESA antibody
  • MGC53915 antibody
  • MGC89222 antibody
  • MVCD5 antibody
  • Pon antibody
  • PON1 antibody
  • pon2 antibody

Protein level used designations for anti-Paraoxonase 1 (PON1) Antibodies

paraoxonase 1 , paraoxonase 2 , serum paraoxonase/arylesterase 1-like , A-esterase 1 , K-45 , PON 1 , aromatic esterase 1 , arylesterase B-type , esterase A , paraoxonase B-type , serum aryldiakylphosphatase , serum aryldialkylphosphatase 1 , serum paraoxonase/arylesterase 1 , serum paraoxonase

GENE ID SPECIES
448598 Xenopus (Silurana) tropicalis
463547 Pan troglodytes
699355 Macaca mulatta
100408915 Callithrix jacchus
100436640 Pongo abelii
100602768 Nomascus leucogenys
5444 Homo sapiens
18979 Mus musculus
84024 Rattus norvegicus
475234 Canis lupus familiaris
100048952 Sus scrofa
523798 Bos taurus
100009133 Oryctolagus cuniculus
100721268 Cavia porcellus
101116983 Ovis aries
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