Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The enzyme encoded by PON1 is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Additionally we are shipping Paraoxonase 1 Antibodies (167) and Paraoxonase 1 Proteins (29) and many more products for this protein.
Showing 10 out of 65 products:
Human PON1 ELISA Kit for Sandwich ELISA - ABIN414651
Liang, Lee, Lee, Lee, Lin, Hsu, Wan, Yu, Tsai, Fu, Ting, Sheu: Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome. in Clinica chimica acta; international journal of clinical chemistry 2011
Show all 13 Pubmed References
Rat (Rattus) PON1 ELISA Kit for Sandwich ELISA - ABIN416523
Avci, Bahadir, Tuncel, Bilgici: Influence of ?-tocopherol and ?-lipoic acid on bisphenol-A-induced oxidative damage in liver and ovarian tissue of rats. in Toxicology and industrial health 2014
Prenatal pesticide exposure was associated with higher adolescent body fat content, including android fat deposition, independent of puberty. Girls appeared more susceptible than boys. Furthermore, the association depended on maternal and child PON1 Q192R genotype.
PON1 575GG genotype was found to influence the risk of Ischemic Heart Failure.
PON1 rs662 polymorphism is significantly correlated with increased ankylosing spondylitis risk via inhibiting PON1 activity.
The A-A haplotype frequency of rs854555-rs662 in PON1 was significantly correlated to the increased susceptibility to osteonecrosis of the femoral head (ONFH).The rs662 polymorphism in PON1 may be associated with ONFH susceptibility, but not rs854555 in Han population, northern China. Additionally, haplotype is also a nonignorable risk factor.
the protective role of genetic variants in PON1 towards cardiovascular risk under high polyphenols and anthocyanins consumption, is reported.
Of these, three CpG sites on TNFAIP8 (show TNFAIP8 ELISA Kits) and PON1 genes (corresponding to: cg23917399; cg07086380; and cg07404485, respectively) were significantly differentially methylated between black and non-black individuals.
Low paraoxonase 1 expression is associated with coronary artery disease severity.
During coronary artery bypass grafting PON1 activity toward paraoxon and phenyl acetate significantly decreased after aorta cross clumping and increased directly after operation.
The biochemical results showed significantly lower folate and vitamin B12 (show NDUFB3 ELISA Kits) status in demented patients than controls. Global DNA methylation (show HELLS ELISA Kits) was associated with markers of folate status, creatinine, glucose and PON1 and IL1B (show IL1B ELISA Kits) polymorphisms.
Pesticide-exposed individuals with inherited susceptible metabolic genotypes (particularly, null genotype for GSTM1 (show GSTM1 ELISA Kits) and the PON1 192R allele) appear to have an increased risk of genotoxic DNA damage.
PON1 overexpression protects against AAA (show AAAS ELISA Kits) progression by reducing oxidative stress, apoptosis and inflammation
Paraoxonase 1 (PON1) influence circadian gene expression and period length
results suggest that Hyperhomocysteinemia plays an intricate role in dysfunctional HDL (show HSD11B1 ELISA Kits), owing to the lack of PON1. This contributes to vascular endothelial impairment and atherosclerosis.
Maternal PON1 status modulates the effects of repeated gestational chlorpyrifos oxon exposure on fetal-brain gene expression and on inhibition of both maternal and fetal biomarker enzymes.
5,6-dihydroxyeicosatrienoate-1,5-lactone, a stable metabolite of arachidonic acid, is a potential substrate for PON1.
HDL (show HSD11B1 ELISA Kits) (mostly HDL3), stimulates PON1 antiatherogenic activities in mouse macrophages.
Findings suggest that Pon1 interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis
The study demonstrated a significant decline in PON1 activity which correlates with increased LDL oxidation after 8 months of age in Wistar rats.
PON1 plays a protective role against hepatic derangements, secondary to fat and cholesterol overnutrition. PON1 deficiency is associated with oxidative stress and metabolic alterations leading to liver steatosis.
PON1 is not essential for normal development, function, ageing, and the defense against light damage of the mouse retina.
PON1 behaves as a negative acute phase protein (show ORM1 ELISA Kits) in pigs since a significant decrease (P<0.05) in its activity after 72 h of the induction of the inflammation was observed with all substrates.
characterization the SNPs in the promoter region of the bovine PON1 gene, and to evaluation of association with serum PON1 activity in periparturient Holstein cows
The results suggest that PON1 might be a better parameter for minimal redox state changes in serum, shortly after labour in the examined breeds.
Data indicate that Cu(2+), Mn(2+), Zn(2+), Ni(2 (show VMP1 ELISA Kits)+), and Pb(2+) were found to inhibite the paraoxonase 1 (PON1) enzyme activity in a concentration-dependent fashion.
The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1, 2 and 3 in granulosa cells and PON1 activity in follicular fluid and plasma of dairy cows.
Significantly lower PON1 activity and PON1/high density lipoprotein ratio in lactating cows compared to heifers showed that metabolic efforts during pregnancy, parturition and lactation influence PON1 activity due to oxidative stress.
The activity of PON1 and malondialdehyde in late pregnancy and early lactation in dairy cattle is reported.
ApoE (show APOE ELISA Kits) mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL (show HSD11B1 ELISA Kits) paraoxonase activity
PON1 can decrease the AChE inhibition, and alleviated clinical signs and tissue damage caused by dichlorvos.
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
, paraoxonase 2
, serum paraoxonase/arylesterase 1-like
, A-esterase 1
, PON 1
, aromatic esterase 1
, arylesterase B-type
, esterase A
, paraoxonase B-type
, serum aryldiakylphosphatase
, serum aryldialkylphosphatase 1
, serum paraoxonase/arylesterase 1
, serum paraoxonase